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《工程(英文)》 >> 2017年 第3卷 第3期 doi: 10.1016/J.ENG.2017.03.020

大规模培养光合生物的光生物反应器设计

a Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China
b Key Laboratory of Green Process and Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China
c Nanomaterials Center, School of Chemical Engineering and Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Queensland 4072, Australia

收稿日期: 2016-12-22 修回日期: 2017-04-17 录用日期: 2017-03-09 发布日期: 2017-05-23

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摘要

光合微生物是生产环境友好的目标产品的重要生物资源,光生物反应器是实现这些过程的重要工具。目前,用于光催化的光生物反应器的设计具有挑战性,大多数光反应器仍然采用半经验的方法进行设计和放大。即使对于高效的光生物反应器,由于缺乏对光的传播、流体动力学、传质、细胞生长之间耦合作用的深刻了解,依靠半经验方法设计的反应器具有投资和运行成本高、使用寿命短的缺点,因此迄今为止尚没有一款合适的光生物反应器可用于光合微生物的大规模培养。首先,本文概述了影响光生物反应器性能的关键参数包括光、混合、传质、温度、pH 值、投资和运行成本等,强调了在商业化培养中光生物反应器的寿命、清洁成本和温度控制的重要性。然后,推荐了四种( 即管式光生物反应器、塑料袋式光生物反应器、柱状气升环流式光生物反应器和平板气升环流式光反应器) 可进行光合微生物大规模培养的光生物反应器。最后,阐述了采用计算流体力学这一有力工具进行光生物反应器建模从而实现光生物反应器的理性设计,并分析了当今数学建模的难点,展示了基于机理模型设计光生物反应器的发展前景。

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