[ 1 ] Wang F, Zhang Q, Lu Z, Wang Q, Wang M, Liu Y, et al. Identification of chemical constituents in traditional Chinese medicine formula using HPLC coupled with linear ion trap-Orbitrap MS from high doses of medicinal materials to equivalent doses of formula: study on Xiang-Sha-Liu-Jun-Zi-Jia-Jian granules. J Sep Sci 2016;39(9):1619–27. 链接1

[ 2 ] Shu Y, Chen Y, Qin K, Liu X, Cai B. A study on the chemical compositions of the Yinqiaosan (lonicerae and forsythiae powder) at different time of laterdecoction by gas chromatography mass spectrometry. Pharmacogn Mag 2016;12(46):134–8. 链接1

[ 3 ] Li J, Lin X, Zhang Y, Liu W, Mi X, Zhang J, et al. Preparative purification of bioactive compounds from Flos Chrysanthemi Indici and evaluation of its antiosteoporosis effect. Evid Based Complement Alternat Med 2016;2016:2587201. 链接1

[ 4 ] Li S, Liu S, Pi Z, Song F, Jin Y, Liu Z. Chemical profiling of Fufang-Xialian-capsule by UHPLC–Q-TOF-MS and its antioxidant activity evaluated by in vitro method. J Pharm Biomed Anal 2017;138:289–301. 链接1

[ 5 ] Li P, Su W, Yun S, Liao Y, Liao Y, Liu H, et al. Toward a scientific understanding of the effectiveness, material basis and prescription compatibility of a Chinese herbal formula Dan-hong injection. Sci Rep 2017;7:46266. 链接1

[ 6 ] Zhong YX, Jin XL, Gu SY, Peng Y, Zhang KR, Ou-Yang BC, et al. Integrated identification, qualification and quantification strategy for pharmacokinetic profile study of Guizhi Fuling capsule in healthy volunteers. Sci Rep 2016;6:31364. 链接1

[ 7 ] Moriarty PM, Roth EM, Karns A, Ye P, Zhao SP, Liao Y, et al. Effects of Xuezhikang in patients with dyslipidemia: a multicenter, randomized, placebo-controlled study. J Clin Lipidol 2014;8(6):568–75. 链接1

[ 8 ] Li JJ, Lu ZL, Kou WR, Bolli R, Chen Z, Wu YF, et al. Impact of long-term Xuezhikang therapy on cardiovascular events in high-risk patients with nonspecific, preexisting abnormal liver tests: a post-hoc analysis from Chinese Coronary Secondary Prevention Study (CCSPS). Int J Cardiol 2012;154(3):362–5. 链接1

[ 9 ] Huang J, Tang X, Ye F, He J, Kong X. Clinical therapeutic effects of aspirin in combination with Fufang Danshen Diwan, a traditional Chinese medicine formula, on coronary heart disease: a systematic review and meta-analysis. Cell Physiol Biochem 2016;39(5):1955–63. 链接1

[10] Bauer R, Franz G. Modern European monographs for quality control of Chinese herbs. Planta Med 2010;76(17):2004–11. 链接1

[11] Chan K, Leung KS, Zhao SS. Harmonization of monographic standards is needed to ensure the quality of Chinese medicinal materials. Chin Med 2009;4:18. 链接1

[12] Hu Y, Jiang Z, Leung KS, Zhao Z. Simultaneous determination of naphthoquinone derivatives in Boraginaceous herbs by high-performance liquid chromatography. Anal Chim Acta 2006;577(1):26–31. 链接1

[13] Zhao Z, Hu Y, Liang Z, Yuen JP, Jiang Z, Leung KS. Authentication is fundamental for standardization of Chinese medicines. Planta Med 2006;72(10):865–74. 链接1

[14] Liu CX, Chen SL, Xiao XH, Zhang TJ, Hou WB. Liao ML. A new concept on quality marker of Chinese materia medica: quality control for Chinese medicinal products. Chin Tradit Herb Drugs 2016;47(9):1443–57. Chinese. 链接1

[15] Liu CX, Cheng YY, Guo DA, Zhang TJ, Li YZ, Hou WB, et al. A new concept on quality marker for quality assessment and process control of Chinese medicines. Chin Herb Med 2017;9(1):3–13. 链接1

[16] Zhang TJ, Xu J, Han YQ, Zhang HB, Gong SX, Liu CX. Quality markers research on Chinese material medica: quality evaluation and quality standards of Corydalis Rhizoma. Chin Tradit Herb Drugs 2016;47(9):1458–67. Chinese. 链接1

[17] Xiong L, Peng C. Study on Q-marker of Leonurus japonicus and Penthorum chinense based on basic conditions of Q-marker. Chin Tradit Herb Drugs 2016;47(13):2212–20. Chinese. 链接1

[18] Jiang CX, Zhang TJ, Chen CQ, Li XK. Liu CX. Research progress in Polygonati Rhizoma and predictive analysis on Q-marker. Chin Tradit Herb Drugs 2017;48 (1):1–16. Chinese. 链接1

[19] Yang W, Zhang Y, Wu W, Huang L, Guo D, Liu C. Approaches to establish Qmarkers for the quality standards of traditional Chinese medicines. Acta Pharm Sin B 2017;7(4):439–46. 链接1

[20] Han YQ, Xu J, Gong SX, Zhang TJ, Liu CX. Chemical constituents and mechanism of Corydalis Rhizoma based on HPLC–QTOF/MS and G protein-coupled receptor analysis. Acta Pharm Sin 2016;51(8):1302–8. Chinese. 链接1

[21] Zhang TJ, Xu J, Shen XP, Han YQ, Hu JF, Zhang HB, et al. Relation of ‘‘propertyresponse-component” and action mechanism of Yuanhu Zhitong dropping pills based on quality marker (Q-marker). Chin Tradit Herb Drugs 2016;47 (13):2199–211. Chinese. 链接1

[22] Ling S, Dai A, Guo Z, Yan X, Komesaroff PA. Effects of a Chinese herbal preparation on vascular cells in culture: mechanisms of cardiovascular protection. Clin Exp Pharmacol Physiol 2005;32(7):571–8. 链接1

[23] Du GH, Zhang JT. The general situation and progress of the modern research of red sage root (Radix Salviae miltiorrhizae). Her Med 2004;23(7):435–40. Chinese. 链接1

[24] Fan HW, Yu L, Hong M, Zhu Q. Establishment of platelet membrane immobilized chromatography and its application in the analysis of active components of Radix Salviae miltiorrhiza. Chin Pharm J 2004;39(5):375–8. Chinese. 链接1

[25] Lay IS, Chiu JH, Shiao MS, Lui WY, Wu CW. Crude extract of Salvia miltiorrhiza and salvianolic acid B enhance in vitro angiogenesis in murine SVR endothelial cell line. Planta Med 2003;69(1):26–32. 链接1

[26] Li MH, Chen JM, Peng Y, Wu Q, Xiao PG. Investigation of Danshen and related medicinal plants in China. J Ethnopharmacol 2008;120(3):419–26. 链接1

[27] He C, Wei JH, Jin Y, Chen SL. Bioactive components of the roots of Salvia miltiorrhizae: changes related to harvest time and germplasm line. Ind Crops Prod 2010;32(3):313–7. 链接1

[28] Huang HX, Qu HB. A comparative fingerprint study using high-performance liquid chromatography, ultraviolet, and near-infrared spectroscopy to evaluate the quality consistency of Danshen injections produced by different manufacturers. Anal Methods 2013;5(2):474–82. 链接1

[29] Wei YJ, Li SL, Li P. Simultaneous determination of seven active components of Fufang Danshen tablet by high performance liquid chromatography. Biomed Chromatogr 2007;21(1):1–9. 链接1

[30] Song JZ, Qiao CF, Li SL, Han QB, Xu HX. Quality assessment of granule of Danshen extract by high performance liquid chromatography. Chin J Nat Med 2009;7(5):368–75. 链接1

[31] Yan KJ, Chu Y, Huang JH, Jiang MM, Li W, Wang YF, et al. Qualitative and quantitative analyses of compound Danshen extract based on 1 H NMR method and its application for quality control. J Pharm Biomed Anal 2016;131:183–7. 链接1

[32] Zhou L, Chow M, Zuo Z. Improved quality control method for Danshen products—consideration of both hydrophilic and lipophilic active components. J Pharm Biomed Anal 2006;41(3):744–50. 链接1

[33] Liu AH, Lin YH, Yang M, Guo H, Guan SH, Sun JH, et al. Development of the fingerprints for the quality of the roots of Salvia miltiorrhiza and its related preparations by HPLC-DAD and LC–MS(n). J Chromatogr B Analyt Technol Biomed Life Sci 2007;846(1–2):32–41. 链接1

[34] Li W, Zhou SP, Jin YP, Huang XF, Zhou W, Han M, et al. Salvianolic acids T and U: a pair of atropisomeric trimeric caffeic acids derivatives from root of Salvia miltiorrhiza. Fitoterapia 2014;98:248–53. 链接1

[35] Li W, Polachi N, Wang X, Chu Y, Wang Y, Tian M, et al. A quality marker study on salvianolic acids for injection. Phytomedicine 2018;44:138–47. 链接1

[36] Pang X, Shi L, Song J, Chen X, Chen S. Use of the potential DNA barcode ITS2 to identify herbal materials. J Nat Med 2013;67(3):571–5. 链接1

[37] Qin Y, Wang JB, Zhao YL, Shan LM, Li BC, Fang F, et al. Establishment of a bioassay for the toxicity evaluation and quality control of Aconitum herbs. J Hazard Mater 2012;199–200:350–7. 链接1

[38] Zhang T, Bai G, Han Y, Xu J, Gong S, Li Y, et al. The method of quality marker research and quality evaluation of traditional Chinese medicine based on drug properties and effect characteristics. Phytomedicine 2018;44:204–11. 链接1

[39] Wu X, Zhang H, Fan S, Zhang Y, Yang Z, Fan S, et al. Quality markers based on biological activity: a new strategy for the quality control of traditional Chinese medicine. Phytomedicine 2018;44:103–8. 链接1

[40] Bai G, Zhang T, Hou Y, Ding G, Jiang M, Luo G. From quality markers to data mining and intelligence assessment: a smart quality-evaluation strategy for traditional Chinese medicine based on quality markers. Phytomedicine 2018;44:109–16. 链接1

[41] He J, Feng X, Wang K, Liu C, Qiu F. Discovery and identification of quality markers of Chinese medicine based on pharmacokinetic analysis. Phytomedicine 2018;44:182–6. 链接1

[42] Wu JJ, Guo ZZ, Zhu YF, Huang ZJ, Gong X, Li YH, et al. A systematic review of pharmacokinetic studies on herbal drug Fuzi: implications for Fuzi as personalized medicine. Phytomedicine 2018;44:187–203. 链接1

[43] Zhong Y, Zhu J, Yang Z, Shao Q, Fan X, Cheng Y. Q-marker based strategy for CMC research of Chinese medicine: a case study of Panax Notoginseng saponins. Phytomedicine 2018;44:129–37. 链接1

[44] Jiang Z, Yang J, Wang Y. Discrimination and identification of Q-markers based on ‘spider-web’ mode for quality control of traditional Chinese medicine. Phytomedicine 2018;44:98–102. 链接1

[45] Tang ZS, Liu YR, Lv Y, Duan JA, Chen SZ, Sun J, et al. Quality markers of animal medicinal materials: correlative analysis of musk reveals distinct metabolic changes induced by multiple factors. Phytomedicine 2018;44:258–69. 链接1

[46] Liu WL, Zhang XL, Fan SQ, Zhu JP, Liang HH, Zhang YT, et al. A novel concept of Q-markers: molecular connectivity index. Phytomedicine 2018;45:36–40. 链接1

[47] Xiong Y, Hu Y, Li F, Chen L, Dong Q, Wang J, et al. Promotion of quality standard of Chinese herbal medicine by the integrated and efficacy-oriented quality marker of effect-constituent index. Phytomedicine 2018;45:26–35. 链接1

[48] Li K, Li J, Su J, Xiao X, Peng X, Liu F, et al. Identification of quality markers of Yuanhu Zhitong tablets based on integrative pharmacology and data mining. Phytomedicine 2018;44:212–9. 链接1

[49] Hou JJ, Cao CM, Xu YW, Yao S, Cai LY, Long HL, et al. Exploring lipid markers of the quality of coix seeds with different geographical origins using supercritical fluid chromatography mass spectrometry and chemometrics. Phytomedicine 2018;45:1–7. 链接1

[50] Huang BM, Zha QL, Chen TB, Xiao SY, Xie Y, Luo P, et al. Discovery of markers for discriminating the age of cultivated ginseng by using UHPLC–QTOF/MS coupled with OPLS-DA. Phytomedicine 2018;45:8–17. 链接1

[51] Ye J, Gao Y, Tian S, Su J, Zhang W. A novel and effective mode-switching triple quadrupole mass spectrometric approach for simultaneous quantifi- cation of fifteen ginsenosides in Panax ginseng. Phytomedicine 2018;44: 164–72. 链接1

[52] Zhang YT, Xiao MF, Liao Q, Liu WL, Deng KW, Zhou YQ, et al. Application of TQSM polypharmacokinetics and its similarity approach to ascertain Q-marker by analyses of transitivity in vivo of five candidates in Buyanghuanwu injection. Phytomedicine 2018;45:18–25. 链接1

[53] Li Z, Liu J, Zhang D, Du X, Han L, Lv C, et al. Nuciferine and paeoniflorin can be quality markers of Tangzhiqing tablet, a Chinese traditional patent medicine, based on the qualitative, quantitative and dose-exposure-response analysis. Phytomedicine 2018;44:155–63. 链接1

[54] Zhang H, Wu X, Xu J, Gong S, Han Y, Zhang T, et al. The comparative pharmacokinetic study of Yuanhu Zhitong prescription based on five qualitymarkers. Phytomedicine 2018;44:148–54. 链接1