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Frontiers of Medicine >> 2011, Volume 5, Issue 2 doi: 10.1007/s11684-011-0140-z

Construction of the vessel-collateral theory and its guidance for prevention and treatment of vasculopathy

1. Integration of Traditional and Western Medical Research Academy of Hebei, Shijiazhuang 050035, China; 2. Key Research Center of State Administration of Traditional Chinese Medicine (Cardiovascular Collateral Disease), Shijiazhuang 050035, China

Available online: 2011-06-05

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Abstract

According to the self-discipline of traditional Chinese medicine, vessel-collateral theory was constructed systematically, which was important to improving prevention and treatment level of vasculopathy. The hypothesis of “homeostasis ( ), compensatory auto-adaptation ( ), regulation ( ) and equilibrium ( )” based on the “qi–yin-yang–five elements” coupled with the (nutrients)- (defense) theory, has become the core content of the vessel-collateral theory. Clinical and laboratory trials have been developed to further confirm the scientific connotations of the hypothesis, such as capsule, as the representative drugs of vessel collateral theory, showed good efficacy in protecting the vascular endothelium, stabilizing the vulnerable plaque and reducing the blood vessel spasm. “Sou, ti, shu, tong” was the characteristics of capsule in treating “microvascular damage” as the core mechanism of acute myocardial infarction, cerebral infarction and microvascular complications of diabetes. capsules in the treatment of arrhythmia have made integrated adjustment advantage. capsules have been made treating both manifestation and root cause of chronic heart failure. These research have improved prevention and treatment level of major vascular system diseases.

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