. Department of Gastroenterology, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China.. School of Biomedical Informatics, The University of Texas Health Science Center at Houston, 7000 Fannin St, Houston, TX 77030, USA;.. Digestive Diseases and Nutrition Center, Department of Pediatrics, The State University of New York at Buffalo, Buffalo, NY 14260, USA;.. Basic Medical College, Beijing University of Chinese Medicine, Beijing 100029, China;.. Genome, Environment and Microbiome Community of Excellence, The State University of New York at Buffalo, Buffalo, NY 14214, USA