Green plant protection is an underlying principle of sustainable agriculture, with less dependence on synthetic chemical pesticides and fertilizers, and more use of the innate ability of crop plants to resist diseases. A new potential direction for green plant protection involves activating host plants' endoplasmic reticulum (ER) stress-mediated immunity, which is induced by pathogen infection. Thus, it is crucial to understand how pathogens break through ER stress-mediated immunity for successful colonization. This image shows the Phytophthora sojae effector PsAvh262 co-localized with the host susceptibility factor GmBiP1 to the ER and extrahaustorial membrane during infection. PsAvh262 then stabilizes the GmBiP1, resulting in the suppression of ER stress-mediated immunity and programmed cell death. In this image, PsAvh262 or GmBiP1 was fused with green or red fluorescent protein, respectively.