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Current advances for bone regeneration based on tissue engineering strategies

Rui Shi, Yuelong Huang, Chi Ma, Chengai Wu, Wei Tian

Frontiers of Medicine 2019, Volume 13, Issue 2, Pages 160-188 doi: 10.1007/s11684-018-0629-9

Abstract: Bone tissue engineering (BTE) is a rapidly developing strategy for repairing critical-sized bone defectsto address the unmet need for bone augmentation and skeletal repair.Effective therapies for bone regeneration primarily require the coordinated combination of innovativeHowever, current techniques in bone tissue engineering have not yet reached valid translation into clinicalovercome these shortcomings and facilitate the clinical application of these techniques to enhance bone

Keywords： bone tissue engineering stem cell bone scaffold growth factor bone regeneration

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FGF13 suppresses acute myeloid leukemia by regulating bone marrow niches

Frontiers of Medicine 2022, Volume 16, Issue 6, Pages 896-908 doi: 10.1007/s11684-022-0944-z

Abstract: definite role in the development of acute myeloid leukemia (AML) and emphasize its associations with bonefunctional analyses indicated that FGF13 was not associated with AML driver mutations but was related to boneOverall, FGF13 could serve as an independent prognostic factor for AML, and it was closely related to the bone

Keywords： acute myeloid leukemia FGF13 prognosis immune-related genes bone marrow niches

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Autologous bone marrow stem cell transplantation for the treatment of ulcerative colitis complicated

Hang Xiang,Xiaomei Zhang,Chao Yang,Wenhuan Xu,Xin Ge,Rong Zhang,Ya Qiu,Wanjun Sun,Fan Li,Tianyuan Xiang,Haixu Chen,Zheng Wang,Qiang Zeng

Frontiers of Medicine 2016, Volume 10, Issue 4, Pages 522-526 doi: 10.1007/s11684-016-0485-4

Abstract: Therefore, we performed an autologous bone marrow cells to modulate the immune system with his permissionAutologous bone marrow mononuclear cells were collected and injected locally into the bowel mucosa, andAfter the patient underwent auto bone marrow mononuclear cells transplantations twice, the patient&rsquo

Keywords： autograft bone marrow stem cells ulcerative colitis cell therapy

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Hybrid polymer biomaterials for bone tissue regeneration

Bo Lei, Baolin Guo, Kunal J. Rambhia, Peter X. Ma

Frontiers of Medicine 2019, Volume 13, Issue 2, Pages 189-201 doi: 10.1007/s11684-018-0664-6

Abstract: The review further exemplifies their applications for bone tissue regeneration.

Keywords： hybrid polymer bone regeneration tissue engineering biomaterials

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Machinability of ultrasonic vibration-assisted micro-grinding in biological bone using nanolubricant

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 1, doi: 10.1007/s11465-022-0717-z

Abstract: Bone grinding is an essential and vital procedure in most surgical operations.results showed that U-NJMC provides a novel approach for clinical surgical micro-grinding of biological bone

Keywords： micro-grinding biological bone ultrasonic vibration (UV) nanoparticle jet mist cooling (NJMC) grinding

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Progress of three-dimensional macroporous bioactive glass for bone regeneration

Lijun JI, Yunfeng SI, Ailing LI, Wenjun WANG, Dong QIU, Aiping ZHU

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 4, Pages 470-483 doi: 10.1007/s11705-012-1217-1

Abstract: excellent osteoconductive, osteoinductive, biocompatible and biodegradable properties, and their high boneMacroporous scaffolds made from BGs are in high demand for bone regeneration because they can stimulatevascularized bone ingrowth and they enhance bonding between scaffolds and surrounding tissues.progress in the past few years in preparing three-dimensional macroporous BG and BG/BP scaffolds for bone

Keywords： bioactive glass biopolymer bone regeneration macroporous scaffolds tissue engineering

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Thermochemical pretreatment of meat and bone meal and its effect on methane production

Guangxue WU , Zhenhu HU , Mark G. HEALY , Xinmin ZHAN ,

Frontiers of Environmental Science & Engineering 2009, Volume 3, Issue 3, Pages 300-306 doi: 10.1007/s11783-009-0031-6

Abstract: Since the solubilization of meat and bone meal (MBM) is a prerequisite in many MBM disposal approaches

Keywords： thermochemical pretreatment meat and bone meal solid reduction solid solubilization methane production

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Bone metastasis of hepatocellular carcinoma: facts and hopes from clinical and translational perspectives

Frontiers of Medicine 2022, Volume 16, Issue 4, Pages 551-573 doi: 10.1007/s11684-022-0928-z

Abstract: Patients with hepatocellular carcinoma (HCC) and bone metastasis (BM) suffer from greatly reduced lifeWe further delineate an informative cancer bone metastatic cascade based on evidence from recent studiesand point out the main factors responsible for the tumor-associated disruption of bone homeostasis and

Keywords： HCC bone osteotropism clinical basic researches advances

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Identification of differentially expressed miRNAs associated with chronic kidney disease–mineral bone

Kyung Im Kim, Sohyun Jeong, Nayoung Han, Jung Mi Oh, Kook-Hwan Oh, In-Wha Kim

Frontiers of Medicine 2017, Volume 11, Issue 3, Pages 378-385 doi: 10.1007/s11684-017-0541-8

Abstract: expressed mRNA in chronic kidney disease (CKD) to predict putative microRNA (miRNA) in CKD–mineral bone

Keywords： chronic kidney disease microRNA mineral bone disorder uremia

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FGF23 associated bone diseases

Eryuan Liao

Frontiers of Medicine 2013, Volume 7, Issue 1, Pages 65-80 doi: 10.1007/s11684-013-0254-6

Abstract: FGF superfamily, the mechanism of FGF23 on phosphate and vitamin D metabolism, and the FGF23 related bone

Keywords： fibroblast growth factor 23 FGF receptor phosphate metabolism Klotho bone disease

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Factors influencing peak bone mass gain

Xiaowei Zhu, Houfeng Zheng

Frontiers of Medicine 2021, Volume 15, Issue 1, Pages 53-69 doi: 10.1007/s11684-020-0748-y

Abstract: Bone mass is a key determinant of osteoporosis and fragility fractures.Epidemiologic studies have shown that a 10% increase in peak bone mass (PBM) at the population levelLow PBM is possibly due to the bone loss caused by various conditions or processes that occur duringHence, the optimization of lifestyle factors that affect PBM and bone strength is an important strategyreview aims to summarize the available evidence for the common but important factors that influence bone

Keywords： peak bone mass children adolescents genetic risk factors

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Bone regeneration by stem cell and tissue engineering in oral and maxillofacial region

Zhiyuan Zhang

Frontiers of Medicine 2011, Volume 5, Issue 4, Pages 401-413 doi: 10.1007/s11684-011-0161-7

Abstract: Clinical imperatives for the reconstruction of jaw bone defects or resorbed alveolar ridge require newtherapies or procedures instead of autologous/allogeneic bone grafts.cell science and tissue engineering technology, is considered as an ideal alternative strategy for boneThe preclinical animal models for bone regeneration and the key translational points to clinical success

Keywords： bone regeneration animal models translational strategies oral and maxillofacial region

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Measurement of bone alkaline phosphatase and relative study with osteosarcoma

YANG Zhiping, LI Jianmin, LI Xin, HUO Yanqing, SUN Guangzhi

Frontiers of Medicine 2007, Volume 1, Issue 1, Pages 54-57 doi: 10.1007/s11684-007-0011-9

Abstract: The objective of this paper is to explore the value of bone alkaline phosphatase (BALP) for diagnosing

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Effects of exercise therapy on bone mineral density in early postmenopausal women: a controlled trial

Shilin DENG MD ,

Frontiers of Medicine 2009, Volume 3, Issue 3, Pages 323-329 doi: 10.1007/s11684-009-0061-2

Abstract: determine the effect of a well-designed combined aerobic, resistance, and extension exercise program on boneAll the subjects had decreased BMD, but the rate of bone loss was lower in the exercise group than inAlthough the exercise program in this study may probably reduce the rate of bone loss in weight-bearingFurther, the exact dose-response relationship of exercise and bone mass in early postmenopause is not

Keywords： early postmenopausal women bone mineral density exercise effects

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Primary cilia in hard tissue development and diseases

Frontiers of Medicine 2021, Volume 15, Issue 5, Pages 657-678 doi: 10.1007/s11684-021-0829-6

Abstract: Bone and teeth are hard tissues.Furthermore, primary cilia act as sensors of external stimuli and regulate bone homeostasis.In this review, we summarize the roles of primary cilia in long bone development and remodeling from

Keywords： primary cilia bone mechanical sensing hard tissue cilium-related bone disease tooth