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Susceptibility of male and female Japanese medaka (

Nannan LIU, Mei MA, Yiping XU, Jinmiao ZHA, Kaifeng RAO, Zijian WANG

Frontiers of Environmental Science & Engineering 2013, Volume 7, Issue 1,   Pages 77-84 doi: 10.1007/s11783-012-0466-z

Abstract: 2,4,6-trichlorophenol (2,4,6-TCP) is a widespread probable human carcinogen and has been proven to have genotoxicity in assays. However, little genotoxicity information and no micronuclei induction data for 2,4,6-TCP is available from tests, especially for sex-specific differences. Following a preliminary test, a piscine peripheral erythrocyte micronucleus assay was conducted on medaka ( ) after a 28-day exposure to 2,4,6-TCP. In the present study, the mean micronuclei (MNC) frequencies of all of the groups increased in a dose-dependent manner, which indicated the potential genotoxicity of 2,4,6-TCP. Moreover, males were found to be more susceptible compared with females after a 28-day exposure to 2,4,6-TCP in all of the dosed groups above 10 μg·L . This is the first report on the potential of micronuclei induction and a sex-susceptible effect in the peripheral erythrocytes of mature fish after 2,4,6-TCP exposure.

Keywords： 6-trichlorophenol     genotoxicity     Japanese medaka     piscine micronucleus test in peripheral erythrocytes     gender    

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Gender differences in the relationship between plasma lipids and fasting plasma glucose in non-diabetic

Jie Zheng,Yuzhen Gao,Yuejuan Jing,Xiaoshuang Zhou,Yuanyuan Shi,Yanhong Li,Lihua Wang,Ruiying Wang,Maolian Li,Chuanshi Xiao,Yafeng Li,Rongshan Li

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 477-483 doi: 10.1007/s11684-014-0346-y

Abstract:

The association between dyslipidemia and elevated fasting glucose in type 2 diabetes is well known. In non-diabetes, whether this association still exists, and whether dyslipidemia is an independent risk factor for high fasting plasma glucose (FPG) levels are not clear. This cross-sectional study recruited 3460 non-diabetic Chinese subjects (1027 men, and 2433 women, aged 35–75 years old) who participated in a health survey. Men and women were classified into tertiles by levels of plasma lipids respectively. In women, the prevalence of impaired fasting glucose (IFG) was decreased with increased HDL-C. A stepwise increase in HDL-C was associated with decreasing FPG levels (lowest tertiles, FPG: 5.376±0.018; middle tertiles, 5.324±0.018; highest tertiles, 5.276±0.018 mmol/L; P=0.001). Reversely, FPG levels increased from lowest tertiles to highest tertiles of LDL-C, TC, and TG. we found that women in the first tertile with lower HDL-C level had a 1.75-fold increase in risk of IFG compared with non-diabetic women in the third tertile with higher HDL-C level (OR: 1.75; 95% CI: 1.20--2.56). In men, no significant association was found. We took age, BMI, waist/hip ratio, education, smoking, alcohol drinking, and physical exercise as adjusted variables. In Chinese non-diabetic women, dyslipidemia is independently associated with high levels of FPG; TG, HDL-C, and LDL-C are predictors of IFG independent of BMI and waist/hip ratio.

Keywords： dyslipidemia     plasma lipids     plasma fasting glucose     impaired fasting glucose     non-diabetes    

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Studies of the gonadogenesis, gender differentiation and early stage development of doubled haploid Japanese

Wang Guixing,Zhu Yimei,Hou Jilun,Zhang Xiaoyan,Wang Yufen,Sun Zhaohui,Jiang Xiufeng,Liu Haijin

Strategic Study of CAE 2014, Volume 16, Issue 9,   Pages 33-41

Abstract:

We studied the gonadogenesis, gender differentiation and early stageThe gender differentiation in female doubled haploid was later than the normal one.For the male double haploid, the gender differentiation was basically the same in time with the normal

Keywords： Japanese flounder Paralichthys olivaceus     doubled haploid     gonad     degeneration.    

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More than Target 6.3: A Systems Approach to Rethinking Sustainable Development Goals in a Resource-Scarce World

Qiong Zhang, Christine Prouty, Julie B. Zimmerman, James R. Mihelcic

Engineering 2016, Volume 2, Issue 4,   Pages 481-489 doi: 10.1016/J.ENG.2016.04.010

Abstract: The SDGs represent commitments to reduce poverty, hunger, ill health, gender inequality, environmentalThe leverage points identified from the conceptual model are gender equality, sustainable management

Keywords： Systems thinking     Sanitation     Environmental protection     Gender     Resource recovery     Causal loop diagram     Sustainability    

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Title Author Date Type Operation

Susceptibility of male and female Japanese medaka (

Nannan LIU, Mei MA, Yiping XU, Jinmiao ZHA, Kaifeng RAO, Zijian WANG

Journal Article

Gender differences in the relationship between plasma lipids and fasting plasma glucose in non-diabetic

Jie Zheng,Yuzhen Gao,Yuejuan Jing,Xiaoshuang Zhou,Yuanyuan Shi,Yanhong Li,Lihua Wang,Ruiying Wang,Maolian Li,Chuanshi Xiao,Yafeng Li,Rongshan Li

Journal Article

Studies of the gonadogenesis, gender differentiation and early stage development of doubled haploid Japanese

Wang Guixing,Zhu Yimei,Hou Jilun,Zhang Xiaoyan,Wang Yufen,Sun Zhaohui,Jiang Xiufeng,Liu Haijin

Journal Article

More than Target 6.3: A Systems Approach to Rethinking Sustainable Development Goals in a Resource-Scarce World

Qiong Zhang, Christine Prouty, Julie B. Zimmerman, James R. Mihelcic

Journal Article