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Application of StrucGP in medical immunology: site-specific -glycoproteomic analysis of macrophages
Frontiers of Medicine 2023, Volume 17, Issue 2, Pages 304-316 doi: 10.1007/s11684-022-0964-8
Keywords: macrophage glycoproteome glycopeptides N-glycan structures PD-L1
Achievements in burn surgery over the past 50 years in China
WANG Shiliang
Frontiers of Medicine 2008, Volume 2, Issue 4, Pages 332-336 doi: 10.1007/s11684-008-0063-5
Keywords: immunology scientific nutritional microbiology engineering
Mechanism of arterial remodeling in chronic allograft vasculopathy
Qichang Zheng, Shanglong Liu, Zifang Song
Frontiers of Medicine 2011, Volume 5, Issue 3, Pages 248-253 doi: 10.1007/s11684-011-0149-3
Keywords: transplantation chronic rejection neointimal immunology arterial remodeling allograft vasculopathy
Role of Intrahepatic Regional Immunity in Post-Transplant Cancer Recurrence Review
Jiang Liu,Chung Mau Lo,Kwan Man
Engineering 2022, Volume 10, Issue 3, Pages 57-64 doi: 10.1016/j.eng.2021.11.012
Hepatic malignancy is a major indication for liver transplantation; however, post-transplant cancer recurrence is an emerging clinical challenge affecting long-term outcomes. Pre-transplant tumor biology, staging, and post-transplant immunosuppression regimens have been elucidated as risk factors for recurrent liver cancer. However, increasing evidence indicates that hepatic ischemia and reperfusion (IR) injury to allografts are crucial to providing a favorable immunologic microenvironment for cancer cell invasiveness and metastasis after liver transplantation. The association of severe graft injury in marginal grafts, such as small-for-size or fatty grafts, with lower recurrence-free survival rates in living donor liver transplantations, substantiates the correlation between hepatic IR injury and cancer recurrence. IR have been demonstrated to trigger intrahepatic immunological microenvironment remodeling, including pro-inflammatory responses exacerbating graft injury and anti-inflammatory responses promoting tissue repair. However, the role of regional immunity in post-transplant cancer recurrence is not comprehensively understood. This review describes the up-to-date evidence of the intrahepatic humoral microenvironment and regional regulatory immunological microenvironment induced by IR injury, as well as their roles in cancer recurrence after liver transplantation. A comprehensive understanding of regional immunity will provide novel precise diagnostic, therapeutic, and prognostic strategies for post-transplant cancer recurrence.
Keywords: Liver transplantation Liver cancer Recurrence Immunology
British Society for Immunology Congress 2019
Conference Date: 2 Dec 2019
Conference Place: 英国/英格兰/利物浦
Administered by: British Society for Immunology
17th International Congress of Immunology
Conference Date: 19 Oct 2019
Conference Place: 中国/北京/朝阳
Administered by: 国际免疫学联合会;中国免疫学会
Conference Date: 11 Jun 2019
Conference Place: 中国/山东/青岛
Administered by: 中国免疫学会;《自然-免疫学》;《中国免疫学会英文会刊(细胞与分子免疫学)》
Conference Date: 8 Apr 2019
Conference Place: 中国/江苏/苏州
Administered by: 冷泉港亚洲
Conference Date: 13 Aug 2019
Conference Place: 美国/华盛顿/西雅图
Administered by: International Union of Immunological Societies (IUIS) Veterinary Immunology Committee
Conference Date: 6 Dec 2019
Conference Place: 英国/英格兰/利物浦
Administered by: 英国免疫学会;中国免疫学会
Title Author Date Type Operation
Application of StrucGP in medical immunology: site-specific -glycoproteomic analysis of macrophages
Journal Article
Mechanism of arterial remodeling in chronic allograft vasculopathy
Qichang Zheng, Shanglong Liu, Zifang Song
Journal Article
Role of Intrahepatic Regional Immunity in Post-Transplant Cancer Recurrence
Jiang Liu,Chung Mau Lo,Kwan Man
Journal Article
British Society for Immunology Congress 2019
2 Dec 2019
Conference Information
17th International Congress of Immunology
19 Oct 2019
Conference Information
Nature Conference
11 Jun 2019
Conference Information
Spring Cold Harbor Asia
8 Apr 2019
Conference Information
IVIS 2019
13 Aug 2019
Conference Information
第三届中英免疫学高峰论坛
6 Dec 2019
Conference Information