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Estimation of the minimum effective dose of tramadol for postoperative analgesia in infants using the

Yue’e Dai, Dongxu Lei, Zhenghua Huang, Yan Yin, G. Allen Finley, Yunxia Zuo

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 288-295 doi: 10.1007/s11684-012-0208-4

Abstract: However, the analgesia efficacy of tramadol, particularly its minimum effective dose (MED), is not clear

Keywords: tramadol     minimum effective dose     postoperative analgesia     infants     continual reassessment method    

Developing effective tumor vaccines: basis, challenges and perspectives

XU Qingwen, CHEN Weifeng

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 11-19 doi: 10.1007/s11684-007-0003-9

Abstract: Continued progress in development of effective cancer vaccines depends on the identification of appropriate

Keywords: development     conventional     identification     elucidation     Successful immunotherapy    

Z-scheme CdS/WO on a carbon cloth enabling effective hydrogen evolution

Frontiers in Energy 2021, Volume 15, Issue 3,   Pages 678-686 doi: 10.1007/s11708-021-0768-6

Abstract: Photocatalytic water splitting for hydrogen (H2) generation is a potential strategy to solve the problem of energy crisis and environmental deterioration. However, powder-like photocatalysts are difficult to recycle, and the agglomeration of particles would affect the photocatalytic activity. Herein, a direct Z-scheme CdS/WO3 composite photocatalyst was fabricated based on carbon cloth through a two-step process. With the support of carbon cloth, photocatalysts tend to grow uniformly for further applications. The experimental results showed that the H2 yield of adding one piece of CdS/WO3 composite material was 17.28 μmol/h, which was 5.5 times as compared to that of pure CdS-loaded carbon cloth material. A cycle experiment was conducted to verify the stability of the as-prepared material and the result demonstrated that the H2 generation performance of CdS/WO3 decreased slightly after 3 cycles. This work provides new ideas for the development of recyclable photocatalysts and has a positive significance for practical applications.

Keywords: photocatalysis     CdS/WO3     carbon cloth     Z-scheme     hydrogen evolution    

Determination of effective stress parameter of unsaturated soils: A Gaussian process regression approach

Pijush Samui, Jagan J

Frontiers of Structural and Civil Engineering 2013, Volume 7, Issue 2,   Pages 133-136 doi: 10.1007/s11709-013-0202-1

Abstract: This article examines the capability of Gaussian process regression (GPR) for prediction of effective

Keywords: unsaturated soil     effective stress parameter     Gaussian process regression (GPR)     artificial neural network    

OPPORTUNITIES AND APPROACHES FOR MANIPULATING SOIL-PLANT MICROBIOMES FOR EFFECTIVE CROP NITROGEN USE

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 3,   Pages 333-343 doi: 10.15302/J-FASE-2022450

Abstract:

● Matching nitrification inhibitors with soil properties and nitrifiers is vital to achieve a higher NUE.

Keywords: nitrogen     microbiome     NUE     rhizosphere     phyllosphere     soil food web    

Facile fabrication of dolomite-doped biochar/bentonite for effective removal of phosphate from complex

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 6, doi: 10.1007/s11783-023-1671-7

Abstract:

● Dolomite-doped biochar/bentonite was synthesized for phosphate removal.

Keywords: Biochar-bentonite composite     Dolomite doping     Phosphate adsorption     Polymeric matrix membrane     Adsorption-filtration dual functions     Low-concentration phosphate    

Multistage analysis method for detection of effective herb prescription from clinical data

Kuo Yang, Runshun Zhang, Liyun He, Yubing Li, Wenwen Liu, Changhe Yu, Yanhong Zhang, Xinlong Li, Yan Liu, Weiming Xu, Xuezhong Zhou, Baoyan Liu

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 206-217 doi: 10.1007/s11684-017-0525-8

Abstract:

Determining effective traditional Chinese medicine (TCM) treatments for specific disease conditionscase matching, complex network analysis, and herb set enrichment analysis was proposed to identify effectiveThen, core network extraction and herb set enrichment were combined to detect core effective herb prescriptionsgroups with symptom manifestations were also identified to help investigate the indications of the effective

Keywords: effective prescription detection     herb set enrichment analysis     core network extraction     insomnia     personalized    

UV-LED/P25-based photocatalysis for effective degradation of isothiazolone biocide

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 5, doi: 10.1007/s11783-020-1379-x

Abstract:

• UV-LED with shorter wavelength was beneficial for photocatalytic degradation.

Keywords: Degradation     Photocatalytic     LED     CMIT     P25    

and properties of PES/SPSf loose nanofiltration membranes using SPES as a hydrophilic polymer for the effective

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 10,   Pages 1555-1567 doi: 10.1007/s11705-023-2338-4

Abstract: hydrophilic polymer and adipic acid as a porogen via non-solvent induced phase separation method for effective

Keywords: adipic acid     loose nanofiltration membrane     dye/salt selective separation     steric hindrance     charge effect    

ROOT EXUDATES FROM CANOLA EXHIBIT BIOLOGICAL NITRIFICATION INHIBITION AND ARE EFFECTIVE IN INHIBITING

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 2,   Pages 177-186 doi: 10.15302/J-FASE-2021421

Abstract:

A range of plant species produce root exudates that inhibit ammonia-oxidizing microorganisms. This biological nitrification inhibition (BNI) capacity can decrease N loss and increase N uptake from the rhizosphere. This study sought evidence for the existence and magnitude of BNI capacity in canola ( Brassica napus). Seedlings of three canola cultivars, Brachiaria humidicola(BNI positive) and wheat ( Triticum aestivum) were grown in a hydroponic system. Root exudates were collected and their inhibition of the ammonia oxidizing bacterium, Nitrosospira multiformis, was tested. Subsequent pot experiments were used to test the inhibition of native nitrifying communities in soil. Root exudates from canola significantly reduced nitrification rates of both N. multiformis cultures and native soil microbial communities. The level of nitrification inhibition across the three cultivars was similar to the well-studied high-BNI species B. humidicola. BNI capacity of canola may have implications for the N dynamics in farming systems and the N uptake efficiency of crops in rotational farming systems. By reducing nitrification rates canola crops may decrease N losses, increase plant N uptake and encourage microbial N immobilization and subsequently increase the pool of organic N that is available for mineralization during the following cereal crops.

Keywords: ammonia oxidizing microorganisms / biological nitrification inhibition / farming rotations / nitrogen cycling / nitrogen use efficiency    

The effective large-scale system of mega project

Ren Hong,Zeng Deheng,Zhang Wei,Zhang Jiangao

Strategic Study of CAE 2012, Volume 14, Issue 12,   Pages 75-80

Abstract: concept to identify and streamline size, scope and elements of mega project system, which is called effective

Keywords: mega project     effective large-scale system     contribution degree     correlation degree     cooperative game    

Cytokine storm and translating IL-6 biology into effective treatments for COVID-19

Frontiers of Medicine doi: 10.1007/s11684-023-1044-4

Abstract: As of May 3, 2023, the coronavirus disease 2019 (COVID-19) pandemic has resulted in more than 760 million confirmed cases and over 6.9 million deaths. Several patients have developed pneumonia, which can deteriorate into acute respiratory distress syndrome. The primary etiology may be attributed to cytokine storm, which is triggered by the excessive release of proinflammatory cytokines and subsequently leads to immune dysregulation. Considering that high levels of interleukin-6 (IL-6) have been detected in several highly pathogenic coronavirus-infected diseases, such as severe acute respiratory syndrome in 2002, the Middle East respiratory syndrome in 2012, and COVID-19, the IL-6 pathway has emerged as a key in the pathogenesis of this hyperinflammatory state. Thus, we review the history of cytokine storm and the process of targeting IL-6 signaling to elucidate the pivotal role played by tocilizumab in combating COVID-19.

Keywords: SARS-CoV-2     COVID-19     cytokine storm     interleukin-6     tocilizumab    

Discovery of novel ursolic acid derivatives as effective antimicrobial agents through a ROS-mediated

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 12,   Pages 2101-2113 doi: 10.1007/s11705-023-2361-5

Abstract: In response to the reduction of food production and economic losses caused by plant bacterial diseases, it is necessary to develop new, efficient, and green pesticides. Natural products are rich and sustainable source for the development of new pesticides due to their low toxicity, easy degradation, and eco-friendliness. In this study, we prepared three series of ursolic acid derivatives and assessed their antibacterial ability. Most target compounds exhibited outstanding antibacterial activities. Among them, the relative optimal EC50 values of Xanthomonas oryzae pv. oryzae and Xanthomonas axonopodis pv. citri were 2.23 (A17) and 1.39 (A16) μg·mL–1, respectively. The antimicrobial mechanism showed that compound A17 induced an excessive accumulation and production of reactive oxygen species in bacteria and damaged the cell membrane integrity to kill bacteria. More interestingly, the addition of low concentrations of exogenous hydrogen peroxide enhanced the antibacterial efficacy of compound A17 against Xanthomonas oryzae pv. oryzae. These entertaining results suggested that compound A17 induced an apparent apoptotic behavior in the tested bacteria. Overall, we developed the promising antimicrobial agents that destroyed the redox system of phytopathogenic bacteria, further demonstrating the unprecedented potential of ursolic acid for agricultural applications.

Keywords: ursolic acid     antibacterial activities     reactive oxygen species     apoptosis    

Effects of a dynamic membrane formed with polyethylene glycol on the ultrafiltration of natural organic matter

Boksoon KWON, Noeon PARK, Jaeweon CHO,

Frontiers of Environmental Science & Engineering 2010, Volume 4, Issue 2,   Pages 172-182 doi: 10.1007/s11783-010-0002-y

Abstract: The formation of a dynamic membrane (DM) was investigated using polyethylene glycol (PEG) (molecular weight of 35000 g/mol, concentration of 1 g/L). Two natural organic matters (NOM), Dongbok Lake NOM (DLNOM) and Suwannee River NOM (SRNOM) were used in the ultrafiltration experiments along with PEG. To evaluate the effects of the DM with PEG on ultrafiltration, various transport experiments were conducted, and the analyses of the NOM in the membrane feed and permeate were performed using high performance size exclusion chromatography, and the pore size distribution ( PSD) and molecular weight cut off ( MWCO) were determined. The advantages of DM formed with PEG can be summarized as follows: (1) PEG interferes with NOM transmission through the ultrafiltration membrane pores by increasing the retention coefficient of NOM in UF membranes, and (2) low removal of NOM by the DM is affected by external factors, such as pressure increases during UF membrane filtration, which decreases the PSD and MWCO of UF membranes. However, a disadvantage of the DM with PEG was severe flux decline; thus, one must be mindful of both the positive and negative influences of the DM when optimizing the UF performance of the membrane.

Keywords: dynamic membrane     natural organic matters     ultrafiltration membrane performance     effective PSD     effective    

Cationic organobismuth complex as an effective catalyst for conversion of CO

Xiaowen ZHANG, Weili DAI, Shuangfeng YIN, Shenglian LUO, Chak-Tong AU

Frontiers of Environmental Science & Engineering 2009, Volume 3, Issue 1,   Pages 32-37 doi: 10.1007/s11783-008-0068-y

Abstract: In order to achieve high-efficiency conversion of CO into valuable chemicals, and to exploit new applications of organobismuth compounds, cationic organobismuth complex with 5,6,7,12-tetrahydrodibenz[c,f] azabismocine framework was examined for the first time for the coupling of CO into cyclic carbonates, using terminal epoxides as substrates and tetrabutylammonium halide as co-catalyst in a solvent-free environment under mild conditions. It is shown that the catalyst exhibited high activity and selectivity for the coupling reaction of CO with a wide range of terminal epoxide. The selectivity of propylene carbonates could reach 100%, and the maximum turnover frequency was up to 10740 h at 120°C and 3 MPa CO pressure when tetrabutylammonium iodide was used as co-catalyst. Moreover, the catalyst is environment friendly, resistant to air and water, and can be readily reused and recycled without any loss of activity, demonstrating a potential in industrial application.

Keywords: cationic organobismuth complex     terminal epoxide     carbon dioxide     coupling     cyclic carbonate    

Title Author Date Type Operation

Estimation of the minimum effective dose of tramadol for postoperative analgesia in infants using the

Yue’e Dai, Dongxu Lei, Zhenghua Huang, Yan Yin, G. Allen Finley, Yunxia Zuo

Journal Article

Developing effective tumor vaccines: basis, challenges and perspectives

XU Qingwen, CHEN Weifeng

Journal Article

Z-scheme CdS/WO on a carbon cloth enabling effective hydrogen evolution

Journal Article

Determination of effective stress parameter of unsaturated soils: A Gaussian process regression approach

Pijush Samui, Jagan J

Journal Article

OPPORTUNITIES AND APPROACHES FOR MANIPULATING SOIL-PLANT MICROBIOMES FOR EFFECTIVE CROP NITROGEN USE

Journal Article

Facile fabrication of dolomite-doped biochar/bentonite for effective removal of phosphate from complex

Journal Article

Multistage analysis method for detection of effective herb prescription from clinical data

Kuo Yang, Runshun Zhang, Liyun He, Yubing Li, Wenwen Liu, Changhe Yu, Yanhong Zhang, Xinlong Li, Yan Liu, Weiming Xu, Xuezhong Zhou, Baoyan Liu

Journal Article

UV-LED/P25-based photocatalysis for effective degradation of isothiazolone biocide

Journal Article

and properties of PES/SPSf loose nanofiltration membranes using SPES as a hydrophilic polymer for the effective

Journal Article

ROOT EXUDATES FROM CANOLA EXHIBIT BIOLOGICAL NITRIFICATION INHIBITION AND ARE EFFECTIVE IN INHIBITING

Journal Article

The effective large-scale system of mega project

Ren Hong,Zeng Deheng,Zhang Wei,Zhang Jiangao

Journal Article

Cytokine storm and translating IL-6 biology into effective treatments for COVID-19

Journal Article

Discovery of novel ursolic acid derivatives as effective antimicrobial agents through a ROS-mediated

Journal Article

Effects of a dynamic membrane formed with polyethylene glycol on the ultrafiltration of natural organic matter

Boksoon KWON, Noeon PARK, Jaeweon CHO,

Journal Article

Cationic organobismuth complex as an effective catalyst for conversion of CO

Xiaowen ZHANG, Weili DAI, Shuangfeng YIN, Shenglian LUO, Chak-Tong AU

Journal Article