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Information gathering and processing with fluorescent molecules

Brian DALY,Jue LING,A. Prasanna de SILVA

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 2,   Pages 240-251 doi: 10.1007/s11705-014-1432-z

Abstract: Molecular information gathering and processing — a young field of applied chemistry — is undergoing good growth. The progress is occurring both in terms of conceptual development and in terms of the strengthening of older concepts with new examples. This review critically surveys these two broad avenues. We consider some cases where molecules emulate one of the building blocks of electronic logic gates. We then examine molecular emulation of various Boolean logic gates carrying one, two or three inputs. Some single-input gates are popular information gathering devices. Special systems, such as ‘lab-on-a-molecule’ and molecular keypad locks, also receive attention. A situation deviating from the Boolean blueprint is also discussed. Some pointers are offered for maintaining the upward curve of the field.

Keywords： molecular logic     molecular computation     molecular sensor     fluorescent molecular device     fluorescent sensor    

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Recent advances of small-molecule fluorescent probes for detecting biological hydrogen sulfide

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 34-63 doi: 10.1007/s11705-021-2050-1

Abstract: has realized the study of H2S in subcellular organelles, facilitated by the development of fluorescent

Keywords： hydrogen sulfide     fluorescent probe     reducibility     nucleophilicity     copper sulfide precipitate     hydrogen    

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Fluorescent properties and

Hong GAO,Jie SONG,Shibin SHANG,Zhanqian SONG

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 1,   Pages 106-115 doi: 10.15302/J-FASE-2017133

Abstract: series of dehydroabietic acid-based diarylamines have been synthesized in order to investigate their fluorescentmolecular geometry, HOMO and LUMO energies, and energy gaps are important to predict absorption and fluorescentcarcinoma SMMC-7721, human gastric cancer SGC-7901 and human lung adenocarcinoma A549 cells and strong blue fluorescentThese compounds are potential candidates for fluorescent probes in biological diagnosis.

Keywords： dehydroabietic acid-based diarylamine     DFT study     fluorescent probe     in vitro imaging    

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A novel flavonol-based colorimetric and turn-on fluorescent probe for rapid determination of hydrazine

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 1,   Pages 24-33 doi: 10.1007/s11705-022-2171-1

Abstract: Herein, a novel fluorescent probe 4-oxo-2-styryl-4H-chromen-3-yl thiophene-2-carboxylate (FHTstrips were able to conveniently detect hydrazine of low concentration through distinct naked-eye and fluorescent

Keywords： cinnamaldehyde     3-hydroxychromone derivative     hydrazine     fluorescent probe    

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Novel lysosome-targeted anticancer fluorescent agents used in zebrafish and nude mouse tumour imaging

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 112-120 doi: 10.1007/s11705-021-2075-5

Abstract: both reporting and imaging agents in vitro and in vivo without the need to add other fluorescent

Keywords： fluorescent drug     lysosomal     anticancer     zebrafish     nude-mouse tumour imaging    

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Fluorescent probes and functional materials for biomedical applications

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 10,   Pages 1425-1437 doi: 10.1007/s11705-022-2163-1

Abstract: Due to their simplicity in preparation, sensitivity and selectivity, fluorescent probes have become theIn addition, many long-wavelength fluorescent probes developed have also proven applicable for inHere, we highlight examples of fluorescent probes and functional materials for biological applicationsselected from the special issues “Fluorescent Probes” and “Molecular Sensors and Logic Gates” recently

Keywords： fluorescent probes     imaging     cell     biomedicine     biomolecules    

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A highly selective fluorescent probe for real-time imaging of UDP-glucuronosyltransferase 1A8 in living

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 103-111 doi: 10.1007/s11705-021-2064-8

Abstract: Here, a novel fluorescent probe BDMP was developed based on boron-dipyrromethene (BODIPY) with high sensitivity

Keywords： UDP-glucuronosyltransferase 1A8     fluorescent probe     subtype selectivity     fluorescence imaging    

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Special issue on “Fluorescent probes”

Adam C. Sedgwick, Tony D. James

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 1,   Pages 1-3 doi: 10.1007/s11705-019-1910-4

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Recent advances in small molecule fluorescent probes for simultaneous imaging of two bioactive molecules

Yongqing Zhou, Xin Wang, Wei Zhang, Bo Tang, Ping Li

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 4-33 doi: 10.1007/s11705-021-2041-2

Abstract: Single organic molecule fluorescent probes have been successively developed to simultaneously monitoron summarizing the design strategies, classifications, and bioimaging applications of dual-response fluorescent

Keywords： bioactive molecules     fluorescent probes     in living cells and in vivo     review    

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Enhancement of open circuit voltage in organic solar cells by doping a fluorescent red dye

Qing LI, Junsheng YU, Yue ZANG, Nana WANG, Yadong JIANG

Frontiers in Energy 2012, Volume 6, Issue 2,   Pages 179-183 doi: 10.1007/s11708-012-0177-y

Abstract: circuit voltage ( ) of small-molecule organic solar cells (OSCs) could be improved by doping suitable fluorescent

Keywords： organic solar cells (OSCs)     open circuit voltage     fluorescent dye doping     4-(dicyanomethylene)-2-t-butyl    

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Valorization of agro-industrial fruit peel waste to fluorescent nanocarbon sensor: Ultrasensitive detection

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 3, doi: 10.1007/s11783-021-1461-z

Abstract:

• Transformation of agro-industrial waste to value-added material via green chemistry.

Keywords： Agro-industrial waste     Orange peel     Valorization     Nanodiamond-like carbon     Atropine sulphate     Fluorescence sensing    

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A minimized fluorescent chemosensor array utilizing carboxylate-attached polythiophenes on a chip for

Yui Sasaki, Xiaojun Lyu, Zhoujie Zhang, Tsuyoshi Minami

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 72-80 doi: 10.1007/s11705-021-2037-y

Abstract: Chemosensor arrays have a great potential for on-site applications in real-world scenarios. However, to fabricate on chemosensor array a number of chemosensors are required to obtain various optical patterns for multi-analyte detection. Herein, we propose a minimized chemosensor array composed of only two types of carboxylate-functionalized polythiophene derivatives for the detection of eight types of metal ions. Upon recognition of the metal ions, the polythiophenes exhibited changes in their fluorescence intensity and various spectral shifts. Although both chemosensors have the same polymer backbone and recognition moiety, only the difference in the number of methylene groups contributed to the difference in the fluorescence response patterns. Consequently, the metal ions in aqueous media were successfully discriminated qualitatively and quantitatively by the chemosensor microarray on the glass chip. This study offers an approach for achieving a minimized chemosensor array just by changing the alkyl chain lengths without the necessity for many receptors and reporters.

Keywords： metal ions     polythiophene     chemosensor array     fluorescence     pattern recognition    

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Near-infrared fluorescent probe for fast track of cyclooxygenase-2 in Golgi apparatus in cancer cells

Bhaskar Gurram, Miao Li, Jiangli Fan, Jingyun Wang, Xiaojun Peng

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 1,   Pages 41-52 doi: 10.1007/s11705-019-1796-1

Abstract: Subcellular localization of the NB-C6-CCB preferentially points to the Golgi apparatus and increases the fluorescent

Keywords： cyclooxygenase-2     nile blue     CCB     Golgi apparatus     NIR imaging    

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A simple umbelliferone based fluorescent probe for the detection of nitroreductase

Adam C. Sedgwick, Alex Hayden, Barry Hill, Steven D. Bull, Robert B. P. Elmes, Tony D. James

Frontiers of Chemical Science and Engineering 2018, Volume 12, Issue 2,   Pages 311-314 doi: 10.1007/s11705-017-1697-0

Abstract: A simple nitrobenzyl-umbelliferone (NCOU1) was synthesised containing a nitroreductase (NTR) trigger moiety. The presence of NTR, resulted in the fragmentation of the parent molecule and release of the highly emissive fluorophore umbelliferone an NTR-catalyzed reduction of the nitro group. In the presence of the NTR enzyme, NCOU1 gave rise to a 5-fold increase in fluorescence intensity at 455 nm and was selective for NTR over other reductive enzymes. These results indicate that NCOU1 can be used as a simple assay for the detection of NTR.

Keywords： fragmentation     NCOU1     NTR     nitroreductase     nitrobenzyl-umbelliferone    

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Dual enzyme activated fluorescein based fluorescent probe

Maria L. Odyniec, Jordan E. Gardiner, Adam C. Sedgwick, Xiao-Peng He, Steven D. Bull, Tony D. James

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 1,   Pages 117-121 doi: 10.1007/s11705-018-1785-9

Abstract: presence of -glc, resulted in fragmentation of the parent molecule releasing glucose and the slightly fluorescent

Keywords： chemosensors     dual-activation     GOx     fluorescence     β-glucosidase     molecular logic    

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Title Author Date Type Operation

Information gathering and processing with fluorescent molecules

Brian DALY,Jue LING,A. Prasanna de SILVA

Journal Article

Recent advances of small-molecule fluorescent probes for detecting biological hydrogen sulfide

Journal Article

Fluorescent properties and

Hong GAO,Jie SONG,Shibin SHANG,Zhanqian SONG

Journal Article

A novel flavonol-based colorimetric and turn-on fluorescent probe for rapid determination of hydrazine

Journal Article

Novel lysosome-targeted anticancer fluorescent agents used in zebrafish and nude mouse tumour imaging

Journal Article

Fluorescent probes and functional materials for biomedical applications

Journal Article

A highly selective fluorescent probe for real-time imaging of UDP-glucuronosyltransferase 1A8 in living

Journal Article

Special issue on “Fluorescent probes”

Adam C. Sedgwick, Tony D. James

Journal Article

Recent advances in small molecule fluorescent probes for simultaneous imaging of two bioactive molecules

Yongqing Zhou, Xin Wang, Wei Zhang, Bo Tang, Ping Li

Journal Article

Enhancement of open circuit voltage in organic solar cells by doping a fluorescent red dye

Qing LI, Junsheng YU, Yue ZANG, Nana WANG, Yadong JIANG

Journal Article

Valorization of agro-industrial fruit peel waste to fluorescent nanocarbon sensor: Ultrasensitive detection

Journal Article

A minimized fluorescent chemosensor array utilizing carboxylate-attached polythiophenes on a chip for

Yui Sasaki, Xiaojun Lyu, Zhoujie Zhang, Tsuyoshi Minami

Journal Article

Near-infrared fluorescent probe for fast track of cyclooxygenase-2 in Golgi apparatus in cancer cells

Bhaskar Gurram, Miao Li, Jiangli Fan, Jingyun Wang, Xiaojun Peng

Journal Article

A simple umbelliferone based fluorescent probe for the detection of nitroreductase

Adam C. Sedgwick, Alex Hayden, Barry Hill, Steven D. Bull, Robert B. P. Elmes, Tony D. James

Journal Article

Dual enzyme activated fluorescein based fluorescent probe

Maria L. Odyniec, Jordan E. Gardiner, Adam C. Sedgwick, Xiao-Peng He, Steven D. Bull, Tony D. James

Journal Article