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Regulation of T cell immunity by cellular metabolism
Zhilin Hu, Qiang Zou, Bing Su
Frontiers of Medicine 2018, Volume 12, Issue 4, Pages 463-472 doi: 10.1007/s11684-018-0668-2
T cells are an important adaptive immune response arm that mediates cell-mediated immunity.
Keywords: T cell immunity metabolic pathways nutrient uptake metabolic checkpoints
Metabolism and immunity in breast cancer
Deyu Zhang, Xiaojie Xu, Qinong Ye
Frontiers of Medicine 2021, Volume 15, Issue 2, Pages 178-207 doi: 10.1007/s11684-020-0793-6
Keywords: breast cancer metabolism immunity cancer stem cells
Rhizosphere immunity: targeting the underground for sustainable plant health management
Zhong WEI, Ville-Petri FRIMAN, Thomas POMMIER, Stefan GEISEN, Alexandre JOUSSET, Qirong SHEN
Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 3, Pages 317-328 doi: 10.15302/J-FASE-2020346
Keywords: rhizosphere soil microbiome plant immunity microbial ecology plant health soilborne pathogens
Toll-like receptors in innate immunity and infectious diseases
Min-Hao WU, Ping ZHANG, Xi HUANG,
Frontiers of Medicine 2010, Volume 4, Issue 4, Pages 385-393 doi: 10.1007/s11684-010-0600-x
Keywords: Toll-like receptors innate immunity infectious disease inflammation
Zeyu Chen,Rong Guo,Jianghong Xu,Chuangjun Qiu
Frontiers of Medicine 2016, Volume 10, Issue 4, Pages 490-498 doi: 10.1007/s11684-016-0470-y
This study evaluated the immunogenicity and protective immunity of a Hemophilus influenzaerate of pneumococcus and the inflammation of the middle ear showed the effectiveness of protective immunity
Keywords: conjugate vaccine pneumococcal surface adhesin A Hemophilus influenzae b immunogenicity otitis media
Antitumor immunity of human SART3 gene vaccine against mouse tumor
HE Yu, YANG Shuhua, LIU Yong, LI Tao
Frontiers of Medicine 2008, Volume 2, Issue 1, Pages 51-57 doi: 10.1007/s11684-008-0010-5
Keywords: antitumor therapy occurrence implantation DNA vaccine SART3 DNA
HEMIPTERAN-TRANSMITTED PLANT VIRUSES: RESEARCH PROGRESS AND CONTROL STRATEGIES
Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 1, Pages 98-109 doi: 10.15302/J-FASE-2021389
Keywords: control strategies / feeding / immunity / insect vector / microorganism / plant virus
Gut microbiota and its implications in small bowel transplantation
Chenyang Wang, Qiurong Li, Jieshou Li
Frontiers of Medicine 2018, Volume 12, Issue 3, Pages 239-248 doi: 10.1007/s11684-018-0617-0
The gut microbiota is mainly composed of a diverse population of commensal bacterial species and plays a pivotal role in the maintenance of intestinal homeostasis, immune modulation and metabolism. The influence of the gut microbiota on solid organ transplantation has recently been recognized. In fact, several studies indicated that acute and chronic allograft rejection in small bowel transplantation (SBT) is closely associated with the alterations in microbial patterns in the gut. In this review, we focused on the recent findings regarding alterations in the microbiota following SBT and the potential roles of these alterations in the development of acute and chronic allograft rejection. We also reviewed important advances with respect to the interplays between the microbiota and host immune systems in SBT. Furthermore, we explored the potential of the gut microbiota as a microbial marker and/or therapeutic target for the predication and intervention of allograft rejection and chronic dysfunction. Given that current research on the gut microbiota has become increasingly sophisticated and comprehensive, large cohort studies employing metagenomic analysis and multivariate linkage should be designed for the characterization of host–microbe interaction and causality between microbiota alterations and clinical outcomes in SBT. The findings are expected to provide valuable insights into the role of gut microbiota in the development of allograft rejection and other transplant-related complications and introduce novel therapeutic targets and treatment approaches in clinical practice.
Keywords: gut microbiota small bowel transplantation acute rejection chronic rejection mucosal immunity biomarker
RNA m6A modification and its function in diseases
Jiyu Tong, Richard A. Flavell, Hua-Bing Li
Frontiers of Medicine 2018, Volume 12, Issue 4, Pages 481-489 doi: 10.1007/s11684-018-0654-8
N6-methyladenosine (m6A) is the most common post-transcriptional RNA modification throughout the transcriptome, affecting fundamental aspects of RNA metabolism. m6A modification could be installed by m6A “writers” composed of core catalytic components (METTL3/METTL14/WTAP) and newly defined regulators and removed by m6A “erasers” (FTO and ALKBH5). The function of m6A is executed by m6A “readers” that bind to m6A directly (YTH domain-containing proteins, eIF3 and IGF2BPs) or indirectly (HNRNPA2B1). In the past few years, advances in m6A modulators (“writers,” “erasers,” and “readers”) have remarkably renewed our understanding of the function and regulation of m6A in different cells under normal or disease conditions. However, the mechanism and the regulatory network of m6A are still largely unknown. Moreover, investigations of the m6A physiological roles in human diseases are limited. In this review, we summarize the recent advances in m6A research and highlight the functional relevance and importance of m6A modification in in vitro cell lines, in physiological contexts, and in cancers.
Keywords: RNA modification m6A immunity cancer epigenetics
TCM Views and Treatment on AIDS
Wang Wenkui
Strategic Study of CAE 2004, Volume 6, Issue 1, Pages 44-47
Keywords: TCM views and theatment HIV/AIDS immunity viscera function
Expression of inducible nitric oxide synthase in trophoblasts and deciduas in early medical abortion
Geqing XIA, Chaoying WU
Frontiers of Medicine 2009, Volume 3, Issue 2, Pages 216-219 doi: 10.1007/s11684-009-0028-3
Keywords: mifepristone inducible nitric oxide synthase early pregnancy placental immunity
Ying HUANG, Clement Wesley GNANADURAI, Zhenfang FU
Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 3, Pages 260-267 doi: 10.15302/J-FASE-2016116
Keywords: antiviral blood brain barrier chemokines and cytokines innate immunity rabies virus
Hong LI,Ziding ZHANG
Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 2, Pages 102-112 doi: 10.15302/J-FASE-2016100
Keywords: plant–pathogen interactions systems biology omics plant immunity protein–protein interaction network
Role of Intrahepatic Regional Immunity in Post-Transplant Cancer Recurrence Review
Jiang Liu,Chung Mau Lo,Kwan Man
Engineering 2022, Volume 10, Issue 3, Pages 57-64 doi: 10.1016/j.eng.2021.11.012
Keywords: Liver transplantation Liver cancer Recurrence Immunology
Yilong Yang, Shipo Wu, Yudong Wang, Fangze Shao, Peng Lv, Ruihua Li, Xiaofan Zhao, Jun Zhang, Xiaopeng Zhang, Jianmin Li, Lihua Hou, Junjie Xu, Wei Chen
Engineering 2023, Volume 27, Issue 8, Pages 127-139 doi: 10.1016/j.eng.2022.12.007
Keywords: Adenovirus serotype 5 Vaccine Preexisting immunity Nanoparticles Transgene expression
Title Author Date Type Operation
Rhizosphere immunity: targeting the underground for sustainable plant health management
Zhong WEI, Ville-Petri FRIMAN, Thomas POMMIER, Stefan GEISEN, Alexandre JOUSSET, Qirong SHEN
Journal Article
Toll-like receptors in innate immunity and infectious diseases
Min-Hao WU, Ping ZHANG, Xi HUANG,
Journal Article
Immunogenicity and protective immunity against otitis media caused by pneumococcus in mice of Hib conjugate
Zeyu Chen,Rong Guo,Jianghong Xu,Chuangjun Qiu
Journal Article
Antitumor immunity of human SART3 gene vaccine against mouse tumor
HE Yu, YANG Shuhua, LIU Yong, LI Tao
Journal Article
Gut microbiota and its implications in small bowel transplantation
Chenyang Wang, Qiurong Li, Jieshou Li
Journal Article
RNA m6A modification and its function in diseases
Jiyu Tong, Richard A. Flavell, Hua-Bing Li
Journal Article
Expression of inducible nitric oxide synthase in trophoblasts and deciduas in early medical abortion
Geqing XIA, Chaoying WU
Journal Article
Critical roles of chemokines and cytokines in antiviral innate immune responses during rabies virus infection
Ying HUANG, Clement Wesley GNANADURAI, Zhenfang FU
Journal Article
Systems understanding of plant–pathogen interactions through genome-wide protein–protein interaction networks
Hong LI,Ziding ZHANG
Journal Article
Role of Intrahepatic Regional Immunity in Post-Transplant Cancer Recurrence
Jiang Liu,Chung Mau Lo,Kwan Man
Journal Article