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Effect of salvia miltiorrhiza pretreatment on the CCK and VIP expression in hepatic ischemia-reperfusion-induced

Zhi-Yong ZHANG, Xiao-Ping CHEN, Qi-Ping LU

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 317-322 doi: 10.1007/s11684-010-0035-4

Abstract: The inhibitory effect of different reperfusion periods 45 min following hepatic ischemia on the expressionrandomly divided into four groups: normal control group (CO group), sham-operated group (SO group), ischemia/reperfusion (I/R) injury group (IR group) and salvia miltiorrhiza pretreatment group (SM group).It is suggested that the digestive tract congestion injury caused by liver ischemia can upregulate theexpression of CCK and VIP in the jejunum following reperfusion.

Keywords： hepatic ischemia-reperfusion     digestive tract congestion     cholecystokinin     vasoactive intestinal peptide    

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Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats

Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 368-373 doi: 10.1007/s11684-015-0403-1

Abstract: Glucagon-like peptide-2 (GLP-2) has potent anti-inflammatory effects and protects against experimental ischemia/reperfusion (I/R) injury in pulmonary, intestinal, and myocardial tissue.The first group was the control group; the second group was the vehicle-treated hepatic ischemia/reperfusionA portal triad was created to induce ischemia with a vascular atraumatic clamp.After 40 min, the clamp was released to initiate hepatic reperfusion for 6 h.

Keywords： ischemia/reperfusion     liver     glucagon-like peptide-2     alanine aminotransferase    

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Effect of oxytocin on gastric ischemia-reperfusion injury in rats

ZHANG Wenwen, ZHANG Jianfu, ZHANG Yongmei, XU Ming

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 433-437 doi: 10.1007/s11684-007-0085-4

Abstract: The effect of peripherally administered oxytocin (OT) on gastric ischemia-reperfusion injury (GI-RI)The animal GI-RI model was established by clamping the celiac artery for 30 min to induce ischemia andthen released to allow reperfusion for 1 h, and the degree of GI-RI was assessed by scoring the gastricresults indicated that the oxytocin could significantly protect gastric mucosal against injury induced by ischemia-reperfusion

Keywords： control     significant difference     surgical     statistical significance     Sprague-Dawley    

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Effect of intestinal ischemia/reperfusion injury on leptin and orexin-A levels

LIN Ji, YAN Guangtao, HAO Xiuhua, ZHANG Kai, GAO Xiaoning, LIAO Jie

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 87-92 doi: 10.1007/s11684-007-0017-3

Abstract: The aim of this paper is to explore the effect of intestinal ischemia/reperfusion (I/R) injury on leptinintestinal I/R injury model of rats was made; the rats were grouped according to the time of after 60 min ischemiaCompared with the levels before the injury, serum leptin in 60 min ischemia/30 min reperfusion (I60´R30

Keywords： significant difference     intestinal I/R     transcriptase-polymerase     metabolic     central secretory    

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The second short-term warm ischemia after vascular anastomosis did not affect early renal function recovery

Tao Qiu, Jiangqiao Zhou, Xiuheng Liu, Minghuan Ge, Zhiyuan Chen

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 329-331 doi: 10.1007/s11684-012-0211-9

Abstract: ow in the early phase of reperfusion, which has been found to be protective against renal ischemia-reperfusionthe allograft renal vein was twisted because of the surgeon’s mistake, which caused the warm ischemiaof allograft after reperfusion.The allograft restored blood flow without second reperfusion and cold preservation after 9 min of warmischemia.

Keywords： renal transplantation     vein twist     ischemia-reperfusion injury    

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The early signal substances induced by heat stress in brains of mice

WANG Chunxu, WANG Hanxing

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 391-395 doi: 10.1007/s11684-008-0075-1

Abstract: brains of Kunming mice, six-month-old mice ( = 72) were pretreated with heat stress and subsequent ischemia/reperfusion by clipping of their bilateral cervical common arteries for 7 min.randomly divided into four groups: (1) normal control group; (2) heat stress pretreatment followed by ischemiaand reperfusion group (HS/IR); (3) ischemia and reperfusion group (IR); (4) heat stress group (HS).

Keywords： calcitonin gene-related     subsequent ischemia/reperfusion     computer     cerebrum     CGRP excretion    

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Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 123-129 doi: 10.1007/s11684-017-0563-2

Abstract: barrier destruction is widely observed among patients receiving liver transplant and suffering from ischemia–reperfusion or rejection injuries because of the relationship between the intestine and the liver

Keywords： gut microbial balance     liver transplantation     ischemia–reperfusion     acute rejection    

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Adiponectin: mechanisms and new therapeutic approaches for restoring diabetic heart sensitivity to ischemic post-conditioning

Tingting Wang, Shanglong Yao, Zhengyuan Xia, Michael G. Irwin

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 301-305 doi: 10.1007/s11684-013-0283-1

Abstract:

Systemic inflammatory response following myocardial ischemia-reperfusion injury (IRI) to a specific

Keywords： adiponectin     ischemic post-conditioning     ischemia reperfusion injury     diabetes    

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Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels

Shilei ZHENG, Jingru ZHU, Jiao LI, Shuang ZHANG, Yunfei MA

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 2,   Pages 197-205 doi: 10.15302/J-FASE-2018245

Abstract: activity of rats in an open-field test, which was associated with attenuated neuronal damage induced by ischemiaserum SOD activity was significantly greater, MDA level lower in the leonurine group as compared with ischemiaTaken together, our results demonstrated that leonurine attenuated brain injury during ischemia via antioxidative

Keywords： cerebral ischemia     GABA     neuroprotection     leonurine     SOD    

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Buxu Tongyu Granule Alleviates Myocardial Ischemia by Activating Vascular Smooth Muscle Cell Soluble

Shuang Yang,Yixiu Zhao,Xiaoling Cheng,Tingting Zhan,Jiaying Tian,Xue Liu,Chunyue Ma,Zhiqi Wang,Luying Jin,Qian Liu,Yanli Wang,Jian Huang,Jinhui Wang,Yan Zhang,Baofeng Yang,

Engineering doi: 10.1016/j.eng.2023.06.009

Abstract: Myocardial ischemia is a serious threat to human health, and vascular dysfunction is its main cause.Buxu Tongyu Granule (BXTY) is an effective traditional Chinese medicine (TCM) for treating myocardial ischemiaIn this study, we demonstrate that BXTY ameliorates myocardial ischemia by activating the soluble guanylateThe results showed that BXTY alleviated the symptoms of myocardial ischemia induced by pituitrin in miceIn conclusion, BXTY can improve the symptoms of acute myocardial ischemia in mice, and activating the

Keywords： Myocardial ischemia     Vasomotion     Soluble guanylate cyclase     Buxu Tongyu Granule    

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Fastigial Nucleus Electrical Stimulation and Central Neurogenic Neuroprotection

Dong Weiwei

Strategic Study of CAE 2001, Volume 3, Issue 11,   Pages 32-38

Abstract:

Brian can protect itself from ischemia and/or hypoxia by two distinct mechanisms which probably involvemode of neuroprotection is not restricted to focal ischmia,it also protects the brain against global ischemia

Keywords： neuroprotection     conditioned     fastigial neucleus     stimulation     cerebral ischemia    

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Overexpression of netrin-1 improves neurological outcomes in mice following transient middle cerebral artery occlusion

Haiyan LU, Yongting WANG, Falei YUAN, Jianrong LIU, Lili ZENG, Guo-Yuan YANG

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 86-93 doi: 10.1007/s11684-011-0118-x

Abstract:

Netrin-1 (NT-1) is one of the axon-guiding molecules that are critical for neuronal development. Because of its structural homology to the endothelial mitogens, NT-1 may have similar effects on vascular network formation. NT-1 was shown to be able to stimulate the proliferation and migration of human cerebral endothelial cells in vitro and also promote focal neovascularization in adult brain in vivo. In the present study, we reported the delivery of NT-1 using an adeno-associated virus (AAV) vector (AAV-NT-1) into mouse brain followed by transient middle cerebral artery occlusion (tMCAO). We found that AAV vectors did not elicit a detectable inflammatory response, cell loss or neuronal damage after brain transduction. The level of NT-1 was increased in the AAV-NT-1-transduced tMCAO mice compared with the control mice. Furthermore, the neurobehavioral outcomes were significantly improved in AAV-NT-1-transduced mice compared with the control animals (P<0.05) 7 days after tMCAO. Our data suggests that NT-1 plays a neuronal function recovery role in ischemic brain and that NT-1 gene transfer might present a valuable approach to treat brain ischemic disorders.

Keywords： adeno-associated virus     angiogenesis     gene transfer     ischemia     middle cerebral artery occlusion     netrin-1    

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Astragaloside IV suppresses post-ischemic natural killer cell infiltration and activation in the brain: involvement of histone deacetylase inhibition

Baokai Dou, Shichun Li, Luyao Wei, Lixin Wang, Shiguo Zhu, Zhengtao Wang, Zunji Ke, Kaixian Chen, Zhifei Wang

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 79-90 doi: 10.1007/s11684-020-0783-8

Abstract: Abundant NK cells infiltrated into the ischemic hemisphere on day 1 after brain ischemia, and this infiltrationStrikingly, ASIV reversed NK cell deficiency in the spleen and blood after brain ischemia.deficiency in the periphery, which together contribute to the beneficial effects of ASIV against brain ischemia

Keywords： astragaloside IV     brain ischemia     natural killer cells     histone deacetylase     nuclear factor-κB    

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and neuronal differentiation of hypoxia-conditioned neuronal progenitor cells in rats with cerebral ischemia

Yao Yao, Rui Zhou, Rui Bai, Jing Wang, Mengjiao Tu, Jingjing Shi, Xiao He, Jinyun Zhou, Liu Feng, Yuanxue Gao, Fahuan Song, Feng Lan, Xingguo Liu, Mei Tian, Hong Zhang

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 472-485 doi: 10.1007/s11684-021-0832-y

Abstract: could increase the survival of transplanted neuronal progenitor cells (NPCs) in rats with cerebral ischemia

Keywords： neuronal progenitor cells     resveratrol     cerebral ischemia     neuronal differentiation     mitochondrial metabolism    

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Title Author Date Type Operation

Effect of salvia miltiorrhiza pretreatment on the CCK and VIP expression in hepatic ischemia-reperfusion-induced

Zhi-Yong ZHANG, Xiao-Ping CHEN, Qi-Ping LU

Journal Article

Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats

Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz

Journal Article

Effect of oxytocin on gastric ischemia-reperfusion injury in rats

ZHANG Wenwen, ZHANG Jianfu, ZHANG Yongmei, XU Ming

Journal Article

Effect of intestinal ischemia/reperfusion injury on leptin and orexin-A levels

LIN Ji, YAN Guangtao, HAO Xiuhua, ZHANG Kai, GAO Xiaoning, LIAO Jie

Journal Article

The second short-term warm ischemia after vascular anastomosis did not affect early renal function recovery

Tao Qiu, Jiangqiao Zhou, Xiuheng Liu, Minghuan Ge, Zhiyuan Chen

Journal Article

The early signal substances induced by heat stress in brains of mice

WANG Chunxu, WANG Hanxing

Journal Article

Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Journal Article

Adiponectin: mechanisms and new therapeutic approaches for restoring diabetic heart sensitivity to ischemic post-conditioning

Tingting Wang, Shanglong Yao, Zhengyuan Xia, Michael G. Irwin

Journal Article

Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels

Shilei ZHENG, Jingru ZHU, Jiao LI, Shuang ZHANG, Yunfei MA

Journal Article

Buxu Tongyu Granule Alleviates Myocardial Ischemia by Activating Vascular Smooth Muscle Cell Soluble

Shuang Yang,Yixiu Zhao,Xiaoling Cheng,Tingting Zhan,Jiaying Tian,Xue Liu,Chunyue Ma,Zhiqi Wang,Luying Jin,Qian Liu,Yanli Wang,Jian Huang,Jinhui Wang,Yan Zhang,Baofeng Yang,

Journal Article

Fastigial Nucleus Electrical Stimulation and Central Neurogenic Neuroprotection

Dong Weiwei

Journal Article

Overexpression of netrin-1 improves neurological outcomes in mice following transient middle cerebral artery occlusion

Haiyan LU, Yongting WANG, Falei YUAN, Jianrong LIU, Lili ZENG, Guo-Yuan YANG

Journal Article

Astragaloside IV suppresses post-ischemic natural killer cell infiltration and activation in the brain: involvement of histone deacetylase inhibition

Baokai Dou, Shichun Li, Luyao Wei, Lixin Wang, Shiguo Zhu, Zhengtao Wang, Zunji Ke, Kaixian Chen, Zhifei Wang

Journal Article

and neuronal differentiation of hypoxia-conditioned neuronal progenitor cells in rats with cerebral ischemia

Yao Yao, Rui Zhou, Rui Bai, Jing Wang, Mengjiao Tu, Jingjing Shi, Xiao He, Jinyun Zhou, Liu Feng, Yuanxue Gao, Fahuan Song, Feng Lan, Xingguo Liu, Mei Tian, Hong Zhang

Journal Article