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Partial liver transplantation

Nianqiao GONG, Xiaoping CHEN

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 1-7 doi: 10.1007/s11684-010-0105-7

Abstract:

Partial liver transplantation, including reduced-size liver transplantation, split liver transplantation, and living donor liver transplantation, has been developed with several innovative techniques becauseSplit liver transplantation provides chances to two or even more recipients when only one liver graftBefore surgery, a series of donor evaluations—including anatomical, liver volume, and liver functionAt different recipient conditions, auxiliary liver transplantation and auxiliary partial orthotopic liver

Keywords: partial liver transplantation     reduced-size liver transplantation     split liver transplantation     living donorliver transplantation    

γδ T cells in liver diseases

Xuefu Wang, Zhigang Tian

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 262-268 doi: 10.1007/s11684-017-0584-x

Abstract: γδ T cells are enriched in the liver and exhibit liver-specific features.fatty liver disease, autoimmune hepatitis, liver fibrosis and cirrhosis, and liver cancer and regenerationWe believe that determining the properties and functions of γδ T cells in liver diseasesenhances our understanding of the pathogenesis of liver diseases and is useful for the design of novelγδ T cell-based therapeutic regimens for liver diseases.

Keywords: γδT cells     liver infection     non-alcoholic fatty liver disease     autoimmune hepatitis     liver fibrosis and cirrhosis     liver cancer     liver regeneration    

NKT cells in liver diseases

Shasha Zhu, Huimin Zhang, Li Bai

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 249-261 doi: 10.1007/s11684-018-0622-3

Abstract: innate-like and tissue-resident lymphocytes, which recognize lipid antigens and are enriched in the livernatural killer T cells and their roles in hepatitis B virus and hepatitis C virus infection, autoimmune liverdiseases, alcoholic liver disease, nonalcoholic fatty liver disease, and hepatocellular carcinoma.and indicate the dynamic alteration in the role of natural killer T cells during the progression of liver

Keywords: natural killer T cells     hepatitis B virus and hepatitis C virus infection     autoimmune liver diseases     alcoholicliver disease     nonalcoholic fatty liver disease     hepatocellular carcinoma    

Natural killer cells in liver diseases

Meijuan Zheng, Haoyu Sun, Zhigang Tian

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 269-279 doi: 10.1007/s11684-018-0621-4

Abstract:

The liver has been characterized as a frontline lymphoid organ with complex immunological featuressuch as liver immunity and liver tolerance.Liver tolerance plays an important role in liver diseases including acute inflammation, chronic infectionThe liver contains a large proportion of natural killer (NK) cells, which exhibit heterogeneity in phenotypicUnder the setting of liver diseases, NK cells are of great importance for stimulating or inhibiting immune

Keywords: natural killer cell     phenotype     immune activation     immune tolerance     liver diseases    

The “Traditional Chinese medicine regulating liver regeneration” treatment plan for reducing mortalityof patients with hepatitis B-related liver failure based on real-world clinical data

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 495-505 doi: 10.1007/s11684-020-0790-9

Abstract: explore the effect and mechanisms of the treatment plan of “traditional Chinese medicine (TCM) regulating liverA total of 457 patients with HBV-related liver failure were retrospectively collected.In addition, there were significant differences in the expression of several cytokines related to liverRLR treatment can decrease jaundice, improve liver function, and significantly reduce the mortality inpatients with HBV-related liver failure.

Keywords: hepatitis B virus-related liver failure     traditional Chinese medicine     liver regeneration     liver regeneration    

Assessment of liver volume variation to evaluate liver function

Cong Tong, Xinsen Xu, Chang Liu, Tianzheng Zhang, Kai Qu

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 421-427 doi: 10.1007/s11684-012-0223-5

Abstract:

In order to assess the value of liver volumetry in cirrhosis and acute liver failure (ALF) patientsto get a regression formula for standard liver volume (SLV) and BSA.It turned out that the mean liver volume of the control group was 1 058±337 cm3.Child A, B level was not reduced, but in Child C level it was significantly reduced with the lowest liverIn conclusion, the CTLV/SLV ratio, which reflects liver volume variations, correlates well with the liver

Keywords: liver volume variation     cirrhosis     acute liver failure (ALF)    

Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 123-129 doi: 10.1007/s11684-017-0563-2

Abstract:

Liver transplantation is a conventional treatment for terminal stage liver diseases.Intestinal barrier destruction is widely observed among patients receiving liver transplant and sufferingThis article reviews the research progress for gut microbial alterations and liver transplantation.microbial alteration and the prediction of possible injuries utilizing microbial alteration during liverand offer a hypothesis on the utilization of microbial alteration in liver transplantation.

Keywords: gut microbial balance     liver transplantation     ischemia–reperfusion     acute rejection    

Molecular mechanisms of fatty liver in obesity

Lixia Gan,Wei Xiang,Bin Xie,Liqing Yu

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 275-287 doi: 10.1007/s11684-015-0410-2

Abstract:

Nonalcoholic fatty liver disease (NAFLD) covers a spectrum of liver disorders ranging from simplesteatosis, which is characterized by excessive accumulation of triglyceride-rich lipid droplets in the liverAccumulating evidence supports that dysregulation of adipose lipolysis and liver de novo&

Keywords: nonalcoholic fatty liver disease     insulin resistance     obesity    

Overview on acute-on-chronic liver failure

Jing Zhang,Shan Gao,Zhongping Duan,Ke-Qin Hu

Frontiers of Medicine 2016, Volume 10, Issue 1,   Pages 1-17 doi: 10.1007/s11684-016-0439-x

Abstract:

Liver failure (LF) is defined as severe dysfunction in hepatic synthesis, detoxification, and metabolism

Keywords: liver failure     chronic liver failure     acute-on-chronic liver failure     diagnosis     prognosis     treatment    

Pyogenic liver abscess as initial presentation in locally advanced right colon cancer invading the liver

Kai Qu, Chang Liu, Aasef M A Mansoor, Bo Wang, Jincai Chen, Liang Yu, Yi Lv

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 434-437 doi: 10.1007/s11684-011-0157-3

Abstract: In the present paper, we report on a patient with advanced right colon cancer, including liver, gallbladder, and duodenal invasion behind the scene of liver abscess.

Keywords: liver abscess     locally advanced colon cancer     multiorganic invasion    

Bioartificial liver devices: Perspectives on the state of the art

Yi-Tao DING, MM, Xiao-Lei SHI, MD

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 15-19 doi: 10.1007/s11684-010-0110-x

Abstract:

Acute liver failure remains a significant cause of morbidity and mortality.Bioartificial liver (BAL) devices have been in development for more than 20 years.Such devices aim to temporarily take over the metabolic and excretory functions of the liver until thepatients’ own liver has recovered or a donor liver becomes available for transplant.failure, and may also be a bridge to liver transplantation.

Keywords: acute liver failure     bioartificial livers     hepatocyte     bioreactor    

Emergency strategies and trends in the management of liver trauma

Hongchi Jiang, Jizhou Wang

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 225-233 doi: 10.1007/s11684-012-0186-6

Abstract:

The liver is the most frequently injured organ during abdominal trauma.Better understanding of the mechanisms and grade of liver injury aids in the initial assessment and establishmentThe grade of liver injury alone does not accurately predict the need for operation, and nonoperativeThe damage control concept is appropriate for the treatment of major liver injuries and is associatedThe present review presents emergency strategies and trends in the management of liver trauma.

Keywords: liver trauma     nonoperative management     operative management    

A better way to do small-for-size liver transplantation in rats

Jiang LI, Yu HOU, Jing LIU, Bin LIU, Li LI

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 106-110 doi: 10.1007/s11684-011-0113-2

Abstract:

Establishing a model for small-for-size liver transplantation is the basis for this study of partialand living donor graft liver transplantation.This study aims to explore a simpler and more effective way of establishing a 30% small-for-size liverSmall-for-size orthotopic liver transplantation was performed using Kamada’s two-cuff method.The donor’s liver was flushed via the abdominal aorta and hepatectomy was performed in situ

Keywords: liver transplantation     small-for-size     rats    

Autoimmune hepatitis

Farhad Sahebjam,John M. Vierling

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 187-219 doi: 10.1007/s11684-015-0386-y

Abstract:

Autoimmune hepatitis is a chronic liver disease putatively caused by loss of tolerance to hepatocyte-specificSince many features also occur in other chronic liver diseases, these scoring systems aid evaluationLiver transplantation represents a life-saving option for patients presenting with acute liver failure

Keywords: autoimmune hepatitis     autoantibodies     diagnosis     immunological diseases     drug-induced liver injury     therapy     immunosuppression     outcomes     hepatocellular carcinoma     liver transplantation    

The influence of brain death on donor liver and the potential mechanisms of protective intervention

Shui-Jun ZHANG, Tao WANG

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 8-14 doi: 10.1007/s11684-011-0109-y

Abstract:

Brain-dead donors have become one of the main sources of organs for transplantation in Western countries. The quality of donor organs is closely related to the outcome of the transplantation. Experimental studies have confirmed the inferior graft survival of livers from brain-dead donors compared with those from living donors. Studies conducted in the past 10 years have shown that brain death is associated with effects on the decreased donor organ quality. However, whether the decrease in the viability of donor organs is caused by brain death or by the events before and after brain death remains uncertain. The purpose of this review is to introduce the advances and controversies regarding the influence of brain death on the viability of donor livers and to summarize the mechanisms of the different protective interventions for donor livers.

Keywords: brain death     donor liver    

Title Author Date Type Operation

Partial liver transplantation

Nianqiao GONG, Xiaoping CHEN

Journal Article

γδ T cells in liver diseases

Xuefu Wang, Zhigang Tian

Journal Article

NKT cells in liver diseases

Shasha Zhu, Huimin Zhang, Li Bai

Journal Article

Natural killer cells in liver diseases

Meijuan Zheng, Haoyu Sun, Zhigang Tian

Journal Article

The “Traditional Chinese medicine regulating liver regeneration” treatment plan for reducing mortalityof patients with hepatitis B-related liver failure based on real-world clinical data

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Journal Article

Assessment of liver volume variation to evaluate liver function

Cong Tong, Xinsen Xu, Chang Liu, Tianzheng Zhang, Kai Qu

Journal Article

Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Journal Article

Molecular mechanisms of fatty liver in obesity

Lixia Gan,Wei Xiang,Bin Xie,Liqing Yu

Journal Article

Overview on acute-on-chronic liver failure

Jing Zhang,Shan Gao,Zhongping Duan,Ke-Qin Hu

Journal Article

Pyogenic liver abscess as initial presentation in locally advanced right colon cancer invading the liver

Kai Qu, Chang Liu, Aasef M A Mansoor, Bo Wang, Jincai Chen, Liang Yu, Yi Lv

Journal Article

Bioartificial liver devices: Perspectives on the state of the art

Yi-Tao DING, MM, Xiao-Lei SHI, MD

Journal Article

Emergency strategies and trends in the management of liver trauma

Hongchi Jiang, Jizhou Wang

Journal Article

A better way to do small-for-size liver transplantation in rats

Jiang LI, Yu HOU, Jing LIU, Bin LIU, Li LI

Journal Article

Autoimmune hepatitis

Farhad Sahebjam,John M. Vierling

Journal Article

The influence of brain death on donor liver and the potential mechanisms of protective intervention

Shui-Jun ZHANG, Tao WANG

Journal Article