Resource Type

Journal Article 12

Conference Videos 1

Year

2023 1

2022 4

2021 2

2020 4

2017 1

2016 1

Keywords

COVID-19 4

Pneumonia 3

2019-nCoV 2

Coronavirus disease 2019 2

7-category ordinal scale 1

Klebsiella pneumonia 1

Antimicrobial resistance 1

COPD 1

Clinical mastitis 1

Clinical trials 1

Computed tomography 1

Core outcome set 1

Coronavirus disease 1

Coronavirus disease 2019 pneumonia 1

Efficacy 1

Fc fragment of the IgG-binding protein 1

Glycosylation 1

Immunoglobulin G 1

Influenza 1

open ︾

Search scope:

排序: Display mode:

Risk factors for ventilator-associated pneumonia among patients undergoing major oncological surgery

Yutao Liu, Yaxia Di, Shuai Fu

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 239-246 doi: 10.1007/s11684-017-0509-8

Abstract: We aimed to identify risk factors for ventilator-associated pneumonia (VAP) in patients undergoing SHNC

Keywords: ventilator-associated pneumonia (VAP)     pneumonia     risk factors     surgery for head and neck cancer (SHNC)    

Analysis of antibiotic usage for viral community-acquired pneumonia in adults

Rongmeng Jiang, Bing Han, Chang Dou, Fei Zhou, Bin Cao, Xingwang Li

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 139-143 doi: 10.1007/s11684-019-0736-2

Abstract: The rationale for the antibiotic treatment of viral community-acquired pneumonia (CAP) in adults wasClinical data from 166 patients diagnosed with viral pneumonia across 14 hospitals in Beijing from NovemberA total of 163 (98.3%) patients with viral pneumonia were treated with antibiotics.

Keywords: adult     antibiotic     viral pneumonia    

Proteomics study of Mycoplasma pneumoniae pneumonia reveals the Fc fragment of the IgG-binding protein

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 378-388 doi: 10.1007/s11684-021-0840-y

Abstract: and corticosteroid resistance has been reported in patients with Mycoplasma pneumoniae (MP) pneumonia

Keywords: severe Mycoplasma pneumoniae pneumonia     children     proteomics     Fc fragment of the IgG-binding protein    

microbiota and important taxa predicting clinical prognosis in patients with severe community-acquired pneumonia

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 389-402 doi: 10.1007/s11684-021-0856-3

Abstract: the key features and prognostic roles of lung microbiota in patients with severe community-acquired pneumonia

Keywords: severe community-acquired pneumonia     lung microbiota     clinical improvements     7-category ordinal scale    

Mouth the mirror of lungs: where does the connection lie?

Jananni Muthu,Sivaramakrishnan Muthanandam,Jaideep Mahendra

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 405-409 doi: 10.1007/s11684-016-0476-5

Abstract:

Periodontitis is the chronic destructive disease of the periodontium (Gums) caused by host bacterial interactions. The effect of such host bacterial interactions in oral cavity also evokes a systemic response. Numerous studies have found common mechanisms of destruction for periodontal diseases and other chronic diseases like diabetes mellitus, atherosclerosis, respiratory diseases, and adverse pregnancy outcomes. Oral colonization by respiratory pathogens appears to be a risk factor for development of respiratory diseases and oral interventions aimed at reducing oral bacterial count have resulted in reduced incidence of these reparatory illness. This reflects the importance of oral hygiene among patients with respiratory illness. This review highlights the association between periodontal diseases and respiratory diseases.

Keywords: periodontitis     respiratory diseases     acute pneumonia     COPD    

Ultrasonic Characteristics and Severity Assessment of Lung Ultrasound in COVID-19 Pneumonia: A Retrospective Article

Fengxue Zhu, Xiujuan Zhao, Tianbing Wang, Zhenzhou Wang, Fuzheng Guo, Haiyan Xue, Panpan Chang, Hansheng Liang, Wentao Ni, Yaxin Wang, Lei Chen, Baoguo Jiang

Engineering 2021, Volume 7, Issue 3,   Pages 367-375 doi: 10.1016/j.eng.2020.09.007

Abstract: clinical application of lung ultrasound (LUS) in the assessment of coronavirus disease 2019 (COVID- 19) pneumoniaHerein, we investigated the role of LUS imaging in COVID-19 pneumonia patients and the relationship betweenLUS detected COVID-19 pneumonia in 38 patients.We conclude that LUS can detect lung lesions in COVID-19 pneumonia patients in a portable, real-time,Thus, LUS is helpful in assessing COVID-19 pneumonia severity in critically ill patients.

Keywords: Coronavirus disease 2019     Lung ultrasound     Pneumonia    

A Deep Learning System to Screen Novel Coronavirus Disease 2019 Pneumonia Article

Xiaowei Xu, Xiangao Jiang, Chunlian Ma, Peng Du, Xukun Li, Shuangzhi Lv, Liang Yu, Qin Ni, Yanfei Chen, Junwei Su, Guanjing Lang, Yongtao Li, Hong Zhao, Jun Liu, Kaijin Xu, Lingxiang Ruan, Jifang Sheng, Yunqing Qiu, Wei Wu, Tingbo Liang, Lanjuan Li

Engineering 2020, Volume 6, Issue 10,   Pages 1122-1129 doi: 10.1016/j.eng.2020.04.010

Abstract: tomography (CT) imaging show individual characteristics that differ from those of other types of viral pneumoniasuch as influenza-A viral pneumonia (IAVP).This study aimed to establish an early screening model to distinguish COVID-19 pneumonia from IAVP and

Keywords: Coronavirus disease 2019 pneumonia     COVID-19     Location-attention classification model     Computed tomography    

China’s local governments are combating COVID-19 with unprecedented responses – from a Wenzhou governance perspective

Fanghua Gong, Yong Xiong, Jian Xiao, Li Lin, Xiaodong Liu, Dezhong Wang, Xiaokun Li

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 220-224 doi: 10.1007/s11684-020-0755-z

Abstract: The COVID-19 caused by a novel strain of coronavirus has been spreading rapidly since its onset in Wuhan, the capital city of central China’s Hubei Province, in December 2019. It is highly communicable through human-to-human transmission. China has been making unprecedented efforts in treating the confirmed cases, identifying and isolating their close contacts and suspected cases to control the source of infection and cut the route of transmission. China’s devotion in handling this epidemic has effectively and efficiently curbed communication domestically and across the border. Representative measures adopted by Wenzhou, the worst hit city out of Hubei Province, are examined to elucidate those massive undertakings with the aim of enhancing international understanding and building global rapport in fighting this evolving epidemic situation.

Keywords: COVID-19     novel coronavirus pneumonia     2019-nCoV     epidemic management    

Molecular Epidemiology of Klebsiella pneumoniae from Clinical Bovine Mastitis in Northern Area of China, 2018–2019 Article

Shikai Song, Wenjuan He, Dawei Yang, Manar Benmouffok, Yao Wang, Jiyun Li, Chengtao Sun, Xiangbin Song, Shizhen Ma, Chang Cai, Shuangyang Ding, Congming Wu, Zhangqi Shen, Yang Wang,

Engineering 2022, Volume 10, Issue 3,   Pages 146-154 doi: 10.1016/j.eng.2021.01.015

Abstract:

Klebsiella pneumoniae (K. pneumonia, KpI) is a predominate

Keywords: Clinical mastitis     Klebsiella pneumonia     Molecular characteristics     Population structure     Antimicrobial    

Differences in Immunoglobulin G Glycosylation Between Influenza and COVID-19 Patients Article

Marina Kljaković-Gašpić Batinjan, Tea Petrović, Frano Vučković, Irzal Hadžibegović, Barbara Radovani, Ivana Jurin, Lovorka Đerek, Eva Huljev, Alemka Markotić, Ivica Lukšić, Irena Trbojević-Akmačić, Gordan Lauc, Ivan Gudelj, Rok Čivljak

Engineering 2023, Volume 26, Issue 7,   Pages 54-62 doi: 10.1016/j.eng.2022.08.007

Abstract:

The essential role of immunoglobulin G (IgG) in immune system regulation and combatting infectious diseases cannot be fully recognized without an understanding of the changes in its N-glycans attached to the asparagine 297 of the Fc domain that occur under such circumstances. These glycans impact the antibody stability, half-life, secretion, immunogenicity, and effector functions. Therefore, in this study, we analyzed and compared the total IgG glycome—at the level of individual glycan structures and derived glycosylation traits (sialylation, galactosylation, fucosylation, and bisecting N-acetylglucosamine (GlcNAc))—of 64 patients with influenza, 77 patients with coronavirus disease 2019 (COVID-19), and 56 healthy controls. Our study revealed a significant decrease in IgG galactosylation, sialylation, and bisecting GlcNAc (where the latter shows the most significant decrease) in deceased COVID-19 patients, whereas IgG fucosylation was increased. On the other hand, IgG galactosylation remained stable in influenza patients and COVID-19 survivors. IgG glycosylation in influenza patients was more time-dependent: In the first seven days of the disease, sialylation increased and fucosylation and bisecting GlcNAc decreased; in the next 21 days, sialylation decreased and fucosylation increased (while bisecting GlcNAc remained stable). The similarity of IgG glycosylation changes in COVID-19 survivors and influenza patients may be the consequence of an adequate immune response to enveloped viruses, while the observed changes in deceased COVID-19 patients may indicate its deviation.

Keywords: Influenza     COVID-19     Viral infection     Glycosylation     Immunoglobulin G     Pneumonia    

The Efficacy and Safety of Triazavirin for COVID-19: A Trial Protocol Protocol

Xiaoke Wu, Kaijiang Yu, Yongchen Wang, Wanhai Xu, Hongli Ma, Yan Hou, Yue Li, Benzhi Cai, Liying Zhu, Min Zhang, Xiaoli Hu, Jingshu Gao, Yu Wang, Huichao Qin, Mingyan Zhao, Yong Zhang, Kang Li, Zhimin Du, Baofeng Yang

Engineering 2020, Volume 6, Issue 10,   Pages 1199-1204 doi: 10.1016/j.eng.2020.06.011

Abstract:

The coronavirus disease 2019 (COVID-19), a pneumonia caused by a novel coronavirus, was reported in

Keywords: Coronavirus disease 2019     Pneumonia     SARS-CoV-2     Triazavirin     Efficacy     Safety    

Core Outcome Set for Clinical Trials on Coronavirus Disease 2019 (COS-COVID) Article

Xinyao Jin, Bo Pang, Junhua Zhang, Qingquan Liu, Zhongqi Yang, Jihong Feng, Xuezheng Liu, Lei Zhang, Baohe Wang, Yuhong Huang, Alice Josephine Fauci, Yuling Ma, Myeong Soo Lee, Wei’an Yuan, Yanming Xie, Jianyuan Tang, Rui Gao, Liang Du, Shuo Zhang, Hanmei Qi, Yu Sun, Wenke Zheng, Fengwen Yang, Huizi Chua, Keyi Wang, Yi Ou, Ming Huang, Yan Zhu, Jiajie Yu, Jinhui Tian, Min Zhao, Jingqing Hu, Chen Yao, Youping Li, Boli Zhang

Engineering 2020, Volume 6, Issue 10,   Pages 1147-1152 doi: 10.1016/j.eng.2020.03.002

Abstract:

Since its outbreak in December 2019, a series of clinical trials on coronavirus disease 2019 (COVID-19) have been registered or carried out. However, the significant heterogeneity and less critical outcomes of such trials may be leading to a waste of research resources. This study aimed to develop a core outcome set (COS) for clinical trials on COVID-19 in order to tackle the outcome issues. The study was conducted according to the Core Outcome Measures in Effectiveness Trials (COMET) Handbook: Version 1.0, a guideline for COS development. A research group was set up that included experts in respiratory and critical medicine, traditional Chinese medicine (TCM), evidence-based medicine, clinical pharmacology, and statistics, in addition to medical journal editors. Clinical trial registry websites (www.chictr.org.cn and clinicaltrials.gov) were searched to retrieve clinical trial protocols and outcomes in order to form an outcome pool. A total of 78 clinical trial protocols on COVID-19 were included and 259 outcomes were collected. After standardization, 132 outcomes were identified within seven different categories, of which 58 were selected to develop a preliminary outcome list for further consensus. After two rounds of Delphi survey and one consensus meeting, the most important outcomes for the different clinical classifications of COVID-19 were identified and determined to constitute the COS for clinical trials on COVID-19 (COS-COVID). The COS-COVID includes one outcome for the mild type (time to 2019 novel coronavirus (2019-nCoV) reverse transcription-polymerase chain reaction (RT-PCR) negativity), four outcomes for the ordinary type (length of hospital stay, composite events, score of clinical symptoms, and time to 2019-nCoV RT-PCR negativity), five outcomes for the severe type (composite events, length of hospital stay, arterial oxygen partial pressure (PaO2)/fraction of inspired oxygen (FiO2), duration of mechanical ventilation, and time to 2019-nCoV RT-PCR negativity), one outcome for critical type (all-cause mortality), and one outcome for rehabilitation period (pulmonary function). The COS-COVID is currently the most valuable and practical clinical outcome set for the evaluation of intervention effect, and is useful for evidence assessment and decision-making. With a deepening understanding of COVID-19 and application feedback, the COS-COVID should be continuously updated.

Keywords: Novel coronavirus pneumonia     Core outcome set     COVID-19     2019-nCoV     Coronavirus disease     Clinical trials    

Title Author Date Type Operation

Risk factors for ventilator-associated pneumonia among patients undergoing major oncological surgery

Yutao Liu, Yaxia Di, Shuai Fu

Journal Article

Analysis of antibiotic usage for viral community-acquired pneumonia in adults

Rongmeng Jiang, Bing Han, Chang Dou, Fei Zhou, Bin Cao, Xingwang Li

Journal Article

Proteomics study of Mycoplasma pneumoniae pneumonia reveals the Fc fragment of the IgG-binding protein

Journal Article

microbiota and important taxa predicting clinical prognosis in patients with severe community-acquired pneumonia

Journal Article

Mouth the mirror of lungs: where does the connection lie?

Jananni Muthu,Sivaramakrishnan Muthanandam,Jaideep Mahendra

Journal Article

Ultrasonic Characteristics and Severity Assessment of Lung Ultrasound in COVID-19 Pneumonia: A Retrospective

Fengxue Zhu, Xiujuan Zhao, Tianbing Wang, Zhenzhou Wang, Fuzheng Guo, Haiyan Xue, Panpan Chang, Hansheng Liang, Wentao Ni, Yaxin Wang, Lei Chen, Baoguo Jiang

Journal Article

A Deep Learning System to Screen Novel Coronavirus Disease 2019 Pneumonia

Xiaowei Xu, Xiangao Jiang, Chunlian Ma, Peng Du, Xukun Li, Shuangzhi Lv, Liang Yu, Qin Ni, Yanfei Chen, Junwei Su, Guanjing Lang, Yongtao Li, Hong Zhao, Jun Liu, Kaijin Xu, Lingxiang Ruan, Jifang Sheng, Yunqing Qiu, Wei Wu, Tingbo Liang, Lanjuan Li

Journal Article

China’s local governments are combating COVID-19 with unprecedented responses – from a Wenzhou governance perspective

Fanghua Gong, Yong Xiong, Jian Xiao, Li Lin, Xiaodong Liu, Dezhong Wang, Xiaokun Li

Journal Article

Molecular Epidemiology of Klebsiella pneumoniae from Clinical Bovine Mastitis in Northern Area of China, 2018–2019

Shikai Song, Wenjuan He, Dawei Yang, Manar Benmouffok, Yao Wang, Jiyun Li, Chengtao Sun, Xiangbin Song, Shizhen Ma, Chang Cai, Shuangyang Ding, Congming Wu, Zhangqi Shen, Yang Wang,

Journal Article

Differences in Immunoglobulin G Glycosylation Between Influenza and COVID-19 Patients

Marina Kljaković-Gašpić Batinjan, Tea Petrović, Frano Vučković, Irzal Hadžibegović, Barbara Radovani, Ivana Jurin, Lovorka Đerek, Eva Huljev, Alemka Markotić, Ivica Lukšić, Irena Trbojević-Akmačić, Gordan Lauc, Ivan Gudelj, Rok Čivljak

Journal Article

Zhu zengyong: Pig Production Restoration and Industrial Form Analysis Under the Covid-19 Pneumonia Situation

18 Apr 2022

Conference Videos

The Efficacy and Safety of Triazavirin for COVID-19: A Trial Protocol

Xiaoke Wu, Kaijiang Yu, Yongchen Wang, Wanhai Xu, Hongli Ma, Yan Hou, Yue Li, Benzhi Cai, Liying Zhu, Min Zhang, Xiaoli Hu, Jingshu Gao, Yu Wang, Huichao Qin, Mingyan Zhao, Yong Zhang, Kang Li, Zhimin Du, Baofeng Yang

Journal Article

Core Outcome Set for Clinical Trials on Coronavirus Disease 2019 (COS-COVID)

Xinyao Jin, Bo Pang, Junhua Zhang, Qingquan Liu, Zhongqi Yang, Jihong Feng, Xuezheng Liu, Lei Zhang, Baohe Wang, Yuhong Huang, Alice Josephine Fauci, Yuling Ma, Myeong Soo Lee, Wei’an Yuan, Yanming Xie, Jianyuan Tang, Rui Gao, Liang Du, Shuo Zhang, Hanmei Qi, Yu Sun, Wenke Zheng, Fengwen Yang, Huizi Chua, Keyi Wang, Yi Ou, Ming Huang, Yan Zhu, Jiajie Yu, Jinhui Tian, Min Zhao, Jingqing Hu, Chen Yao, Youping Li, Boli Zhang

Journal Article