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Journal Article 12

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CD14 2

liver transplantation 2

Adult rats 1

Growth performance 1

Leucine 1

Low-protein diet 1

Muscle weight 1

Protein synthesis 1

Sprague 1

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Zhihuang decoction 1

abdominal aorta coarctation 1

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beta-elemene 1

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bleomycin-induced pulmonary 1

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of RNA interference targeting angiotensin 1a receptor on blood pressure and cardiac hypertrophy of rats

ZHANG Jingqun, SUN Honglei, MA Yexin, WANG Daowen

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 19-24 doi: 10.1007/s11684-008-0005-2

Abstract: interference (RNAi) targeting angiotensin 1a receptor (AT1a) on blood pressure and cardiac hypertrophy of ratsThirty Sprague – Dawley rats with renovascular hypertension (2-kidney 1-clip) were randomly divided intoThe ratio of left ventricle weight to body weight (LV/BW) of the rats in pAT1a-shRNA1, pAT1a-shRNA2,groups decreased significantly than in the control group ( < 0.01), similar to those of the normal SD rats

Keywords： therapy     Sprague     administration     cardiac hypertrophy     valsartan    

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Effect of Feixian Recipe on laminin, collagen I and III in rats with pulmonary fibrosis induced by bleomycin

ZHANG Xiaomei, JIANG Liangduo, ZHANG Wei, WU Jianjun, LU Xiangfeng

Frontiers of Medicine 2008, Volume 2, Issue 3,   Pages 314-316 doi: 10.1007/s11684-008-0060-8

Abstract: The aim of this paper is to observe the effect of the Feixian Recipe on pulmonary fibrosis in rats.Feixian Recipe has a significant therapeutic effect on bleomycin-induced pulmonary fibrosis in rats.

Keywords： bleomycin     intratracheal injection     prednisone     collagen     bleomycin-induced pulmonary    

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Structural shifts in the intestinal microbiota of rats treated with cyclosporine A after orthotropic

Junjun Jia, Xinyao Tian, Jianwen Jiang, Zhigang Ren, Haifeng Lu, Ning He, Haiyang Xie, Lin Zhou, Shusen Zheng

Frontiers of Medicine 2019, Volume 13, Issue 4,   Pages 451-460 doi: 10.1007/s11684-018-0675-3

Abstract: Understanding the effect of immunosuppressive agents on intestinal microbiota is important to reduce the mortality and morbidity from orthotopic liver transplantation (OLT). We investigated the relationship between the commonly used immunosuppressive agent cyclosporine A (CSA) and the intestinal microbial variation in an OLT model. The rat samples were divided as follows: (1) N group (normal control); (2) I group (isograft LT, Brown Norway [BN] rat to BN); (3) R group (allograft LT, Lewis to BN rat); and (4) CSA group (R group treated with CSA). The intestinal microbiota was assayed by denaturing gradient gel electrophoresis profiles and by using real-time polymerase chain reaction. The liver histopathology and the alanine/aspartate aminotransferase ratio after LT were both ameliorated by CSA. In the CSA group, the numbers of rDNA gene copies of cluster I, cluster XIV, and Enterobacteriaceae decreased, whereas those of increased compared with the R group. Cluster analysis indicated that the samples from the N, I, and CSA groups were clustered, whereas the other clusters contained the samples from the R group. Hence, CSA ameliorates hepatic graft injury and partially restores gut microbiota following LT, and these may benefit hepatic graft rejection.

Keywords： microbial community     liver transplantation     immunosuppressive agents     cyclosporine A    

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Alleviation of cell damage in experimental ANP in rats by administration of chondroitin-sulfate reduces

HE Zhongye, GUO Renxuan, LI Yang, XIE Chengyao, LIU Nan, SONG Wen

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 36-40 doi: 10.1007/s11684-007-0007-5

Abstract: cytoprotection and attenuation of oxidative damage during acute necrotic pancreatitis (ANP), male Wistar ratsThe rats in group A was subjected to retrograde injection of 5% sodium taurocholate via the pancreaticAll rats in three groups were killed at 6 h.

Keywords： control     Wistar     taurocholate     superoxide dismutase     chondroitin-sulfate therapy    

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Sensory innervation of the anterior eye segment in rats: a retrograde tracing study

Haixia LIU MD , Zhiwang LI MD , Min YANG MD , Xiang TIAN MS , Chaoying LI PhD , Lei PEI PhD ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 352-356 doi: 10.1007/s11684-009-0065-y

Abstract: This study aimed to investigate the sensory innervation of the anterior eye segment in rats by retrograde

Keywords： trigeminal ganglion     retrograde tracing    

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of beta-elemene on the levels of plasma endotoxin, serum TNF-alpha, and hepatic CD14 expression in rats

Jianguo LIU, Zhe ZHANG, Jiechang GAO, Jiwen XIE, Lin YANG, Shenjun HU

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 101-105 doi: 10.1007/s11684-011-0111-4

Abstract: experimental model was induced by the hypodermical injection of CCl4 in Wistar male ratsβ-elemene was intraperitoneally administered into rats for 8 weeks (0.1 mL/100 g bodyweight percan downregulate the levels of plasma endotoxins, serum TNF-α, and hepatic CD14 expression in rats

Keywords： liver fibrosis     beta-elemene     endotoxin     CD14    

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monocarboxylate transporter 1 aggravates white matter injury after experimental subarachnoid hemorrhage in rats

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 887-902 doi: 10.1007/s11684-021-0879-9

Abstract: In this study, the SAH model of adult male Sprague-Dawley rats was used to explore the role of MCT1 inoligodendrocytes and upregulated the level of MCT1, which was positively correlated with the behavioral ability of ratsIn addition, miR-29b and miR-124 levels were significantly increased in SAH rats compared with non-SAHrats.

Keywords： microRNAs     monocarboxylate transporter 1     motor training     subarachnoid hemorrhage     white matter injury    

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Protective effect of tanshinone II A on signal transduction system protein kinase B in rats with myocardial

Enyuan TU MD, Yongjun PAN MM, Kang ZHENG MM, Zhaohua WANG MD, Qiansheng LIANG MD, Guangtian YANG MD,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 431-436 doi: 10.1007/s11684-009-0088-4

Abstract: The effects of tanshinone II A on cell signal transduction system protein kinase B in rats with myocardialForty-eight rats were randomly divided into sham group (S group), model group (M group), valsartan treatment

Keywords： tanshinone II A     myocardial hypertrophy     rat     protein kinase B     abdominal aorta coarctation    

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A better way to do small-for-size liver transplantation in rats

Jiang LI, Yu HOU, Jing LIU, Bin LIU, Li LI

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 106-110 doi: 10.1007/s11684-011-0113-2

Abstract: explore a simpler and more effective way of establishing a 30% small-for-size liver transplantation in ratsSprague-Dawley rats were selected as the donors and recipients.The animals were divided into three groups depending on the graft selected, with 40 pairs of rats inmay be a more effective and simpler way of establishing a 30% small-for-size liver transplantation in rats

Keywords： liver transplantation     small-for-size     rats    

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promotes the survival and neuronal differentiation of hypoxia-conditioned neuronal progenitor cells in rats

Yao Yao, Rui Zhou, Rui Bai, Jing Wang, Mengjiao Tu, Jingjing Shi, Xiao He, Jinyun Zhou, Liu Feng, Yuanxue Gao, Fahuan Song, Feng Lan, Xingguo Liu, Mei Tian, Hong Zhang

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 472-485 doi: 10.1007/s11684-021-0832-y

Abstract: Hypoxia conditioning could increase the survival of transplanted neuronal progenitor cells (NPCs) in ratsand hcNPC transplantation synergistically improved the neurological and metabolic recovery of stroke ratsconclusion, resveratrol promoted the neuronal differentiation and therapeutic efficiency of hcNPCs in stroke rats

Keywords： neuronal progenitor cells     resveratrol     cerebral ischemia     neuronal differentiation     mitochondrial metabolism     positron emission tomography    

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Weight and Postprandial Protein Synthesis of Skeletal Muscle by Promoting the mTOR Pathway in Adult Rats

Bo Zhang, Licui Chu, Hong Liu, Chunyuan Xie, Shiyan Qiao, Xiangfang Zeng

Engineering 2017, Volume 3, Issue 5,   Pages 760-765 doi: 10.1016/J.ENG.2017.03.008

Abstract: whether leucine supplementation would increase the synthesis rate of protein and muscle weight in adult ratsThirty-six male Sprague-Dawley rats were assigned to one of three dietary treatments including a 20%

Keywords： Low-protein diet     Leucine     Growth performance     Muscle weight     Protein synthesis     Adult rats    

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CD14 expression in lipopolysaccharide signal transduction pathway of alcohol-induced liver disease in rats

Rui ZHU MD , Lin SHEN MD , Jianguo LIU MD , Weili ZHANG MM , Ling YANG MD ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 363-367 doi: 10.1007/s11684-009-0064-z

Abstract: expression in the lipopolysaccharide signal transduction pathway of alcohol-induced liver disease in ratsSeventy-five Wistar rats were randomly divided into three groups.Ethanol (56%, weight/volumn) was intragastrically administrated to 50 rats (14mL/kg body weightper day) for 10 days to establish a model of alcohol-induced liver disease, and 25 of these 50 ratsplasma endotoxin and up-regulation of CD14 was also suppressed by decoction in alcohol-intoxicated rats

Keywords： liver disease     alcohol     Zhihuang decoction     CD14     signal transduction    

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Title Author Date Type Operation

of RNA interference targeting angiotensin 1a receptor on blood pressure and cardiac hypertrophy of rats

ZHANG Jingqun, SUN Honglei, MA Yexin, WANG Daowen

Journal Article

Effect of Feixian Recipe on laminin, collagen I and III in rats with pulmonary fibrosis induced by bleomycin

ZHANG Xiaomei, JIANG Liangduo, ZHANG Wei, WU Jianjun, LU Xiangfeng

Journal Article

Structural shifts in the intestinal microbiota of rats treated with cyclosporine A after orthotropic

Junjun Jia, Xinyao Tian, Jianwen Jiang, Zhigang Ren, Haifeng Lu, Ning He, Haiyang Xie, Lin Zhou, Shusen Zheng

Journal Article

Alleviation of cell damage in experimental ANP in rats by administration of chondroitin-sulfate reduces

HE Zhongye, GUO Renxuan, LI Yang, XIE Chengyao, LIU Nan, SONG Wen

Journal Article

Sensory innervation of the anterior eye segment in rats: a retrograde tracing study

Haixia LIU MD , Zhiwang LI MD , Min YANG MD , Xiang TIAN MS , Chaoying LI PhD , Lei PEI PhD ,

Journal Article

of beta-elemene on the levels of plasma endotoxin, serum TNF-alpha, and hepatic CD14 expression in rats

Jianguo LIU, Zhe ZHANG, Jiechang GAO, Jiwen XIE, Lin YANG, Shenjun HU

Journal Article

monocarboxylate transporter 1 aggravates white matter injury after experimental subarachnoid hemorrhage in rats

Journal Article

Protective effect of tanshinone II A on signal transduction system protein kinase B in rats with myocardial

Enyuan TU MD, Yongjun PAN MM, Kang ZHENG MM, Zhaohua WANG MD, Qiansheng LIANG MD, Guangtian YANG MD,

Journal Article

A better way to do small-for-size liver transplantation in rats

Jiang LI, Yu HOU, Jing LIU, Bin LIU, Li LI

Journal Article

promotes the survival and neuronal differentiation of hypoxia-conditioned neuronal progenitor cells in rats

Yao Yao, Rui Zhou, Rui Bai, Jing Wang, Mengjiao Tu, Jingjing Shi, Xiao He, Jinyun Zhou, Liu Feng, Yuanxue Gao, Fahuan Song, Feng Lan, Xingguo Liu, Mei Tian, Hong Zhang

Journal Article

Weight and Postprandial Protein Synthesis of Skeletal Muscle by Promoting the mTOR Pathway in Adult Rats

Bo Zhang, Licui Chu, Hong Liu, Chunyuan Xie, Shiyan Qiao, Xiangfang Zeng

Journal Article

CD14 expression in lipopolysaccharide signal transduction pathway of alcohol-induced liver disease in rats

Rui ZHU MD , Lin SHEN MD , Jianguo LIU MD , Weili ZHANG MM , Ling YANG MD ,

Journal Article