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Journal Article 1

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2013 1

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aminoglycoside 1

high-performance liquid chromatography 1

ion-pairing 1

refractive index detector 1

tobramycin 1

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Fast determination of tobramycin by reversed-phase ion-pair high performance liquid chromatography with

Liang ZHU, Jingkang WANG

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 3,   Pages 322-328 doi: 10.1007/s11705-013-1348-z

Abstract: A simple and direct method without a derivation step for routine analysis of tobramycin has been developedpresence of 4.50 mg·mL trifluoroacetic acid (TFA) in the mobile phase improved the protonation of tobramycinTobramycin was recovered in 98.00%, 98.84% and 99.64% for tobramycin solutions at concentrations of 2.25

Keywords： tobramycin     aminoglycoside     refractive index detector     high-performance liquid chromatography     ion-pairing    

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Fast determination of tobramycin by reversed-phase ion-pair high performance liquid chromatography with

Liang ZHU, Jingkang WANG

Journal Article