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Journal Article 5

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2023 2

2021 1

2017 1

2012 1

Keywords

Probiotics 3

Gut microbiota 2

Bifidobacterium longum 1

Bile acid (BA) 1

Caco-2 cells 1

Fecal metabolites 1

Gastrointestinal malignancy 1

Health 1

Hyperlipidemia 1

Infectious disease 1

Intestinal barrier 1

Lactobacillus 1

Liver diseases 1

Metabolic diseases 1

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Microbiome 1

Microbiota technology 1

Next-generation probiotics (NGPs) 1

Non-alcoholic fatty liver disease (NAFLD) 1

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Screening of potential aquatic probiotics from the major microflora of guppies (

Aparna BALAKRISHNA, T. R. KEERTHI

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 2,   Pages 163-173 doi: 10.1007/s11705-012-1283-4

Abstract: The fish ( ) was used as the source for probiotics. 46 bacterial isolates were obtained from the skin

Keywords： aquaculture     normal flora     immunomodulatory effect     probiotic     antagonistic principle     bacteriocin like inhibitory substances    

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An Update on the Efficacy and Functionality of Probiotics for the Treatment of Non-Alcoholic Fatty Liver Article

Mingfei Yao, Lingling Qv, Yanmeng Lu, Baohong Wang, Björn Berglund, Lanjuan Li

Engineering 2021, Volume 7, Issue 5,   Pages 679-686 doi: 10.1016/j.eng.2020.01.017

Abstract: >Bifidobacterium and Lactobacillus genera constitute the most widely used traditional probioticsMore recently, emerging next-generation probiotics (NGPs) such as Akkermansia muciniphila andThis review provides an overview of the effects of oral administration of traditional probiotics andThe mechanisms by which probiotics directly or indirectly affect the disease are illustrated, based onfor the treatment of NAFLD, as well as the safety of probiotics in the human body.

Keywords： Non-alcoholic fatty liver disease (NAFLD)     Gut microbiota     Probiotics     Next-generation probiotics (NGPs    

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The Human Microbiota in Health and Disease

Baohong Wang, Mingfei Yao, Longxian Lv, Zongxin Ling, Lanjuan Li

Engineering 2017, Volume 3, Issue 1,   Pages 71-82 doi: 10.1016/J.ENG.2017.01.008

Abstract:

Trillions of microbes have evolved with and continue to live on and within human beings. A variety of environmental factors can affect intestinal microbial imbalance, which has a close relationship with human health and disease. Here, we focus on the interactions between the human microbiota and the host in order to provide an overview of the microbial role in basic biological processes and in the development and progression of major human diseases such as infectious diseases, liver diseases, gastrointestinal cancers, metabolic diseases, respiratory diseases, mental or psychological diseases, and autoimmune diseases. We also review important advances in techniques associated with microbial research, such as DNA sequencing, metabonomics, and proteomics combined with computation-based bioinformatics. Current research on the human microbiota has become much more sophisticated and more comprehensive. Therefore, we propose that research should focus on the host-microbe interaction and on cause-effect mechanisms, which could pave the way to an understanding of the role of gut microbiota in health and disease. and provide new therapeutic targets and treatment approaches in clinical practice.

Keywords： Infectious disease     Liver diseases     Gastrointestinal malignancy     Metabolic disorder     Microbiota technology     Probiotics    

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A Screening Model for Probiotics Against Specific Metabolic Diseases Based on Caco-2 Monolayer Membrane Article

Yang Liu, Jiang Peng, Shiya Zhu, Leilei Yu, Fengwei Tian, Jianxin Zhao, Hao Zhang, Wei Chen, Qixiao Zhai

Engineering 2023, Volume 25, Issue 6,   Pages 222-233 doi: 10.1016/j.eng.2022.02.014

Abstract:

Recent studies have revealed the potency of probiotics in alleviating metabolic diseases associatedcoefficient between the data of cell and animal models were 0.82 and −0.97 for the protection of probioticsrespectively, suggesting the reliability of the cell model to simulate the in vivo protective effects of probioticsvitro approach based on a Caco-2 cell monolayer membrane model for the efficient screening of potential probiotics

Keywords： Lactobacillus     Intestinal barrier     Caco-2 cells     Screening model     Metabolic diseases    

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Bifidobacterium longum CCFM1077 Attenuates Hyperlipidemia by Modulating the Gut Microbiota Composition and Fecal Metabolites: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial Article

Chuanqi Chu, Jinchi Jiang, Leilei Yu, Yiwen Li, Songli Zhang, Wei Zhou, Qun Wang, Jianxin Zhao, Qixiao Zhai, Fengwei Tian, Wei Chen

Engineering 2023, Volume 28, Issue 9,   Pages 193-205 doi: 10.1016/j.eng.2023.04.010

Abstract: These findings provide a foundation for future clinical applications of lipid-lowering probiotics in

Keywords： Probiotics     Bifidobacterium longum     Hyperlipidemia     Gut microbiota     Fecal metabolites     Bile acid    

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Title Author Date Type Operation

Screening of potential aquatic probiotics from the major microflora of guppies (

Aparna BALAKRISHNA, T. R. KEERTHI

Journal Article

An Update on the Efficacy and Functionality of Probiotics for the Treatment of Non-Alcoholic Fatty Liver

Mingfei Yao, Lingling Qv, Yanmeng Lu, Baohong Wang, Björn Berglund, Lanjuan Li

Journal Article

The Human Microbiota in Health and Disease

Baohong Wang, Mingfei Yao, Longxian Lv, Zongxin Ling, Lanjuan Li

Journal Article

A Screening Model for Probiotics Against Specific Metabolic Diseases Based on Caco-2 Monolayer Membrane

Yang Liu, Jiang Peng, Shiya Zhu, Leilei Yu, Fengwei Tian, Jianxin Zhao, Hao Zhang, Wei Chen, Qixiao Zhai

Journal Article

Bifidobacterium longum CCFM1077 Attenuates Hyperlipidemia by Modulating the Gut Microbiota Composition and Fecal Metabolites: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Chuanqi Chu, Jinchi Jiang, Leilei Yu, Yiwen Li, Songli Zhang, Wei Zhou, Qun Wang, Jianxin Zhao, Qixiao Zhai, Fengwei Tian, Wei Chen

Journal Article