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Comparisons in subcellular and biochemical behaviors of cadmium between low-Cd and high-Cd accumulation

Meng XUE, Yihui ZHOU, Zhongyi YANG, Biyun LIN, Jiangang YUAN, Shanshan WU

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 2,   Pages 226-238 doi: 10.1007/s11783-013-0582-4

Abstract: in low-Cd accumulation cultivars and high-Cd accumulation cultivars of pakchoi ( L.).low-Cd cultivars.The high-Cd cultivars had significantly higher leaf and stem Cd concentrations than the low-Cd cultivarsIn low-Cd cultivars, which were more sensitive and thus had greater physiological needs of Cd detoxificationmight be different between low- and high-Cd cultivars.

Keywords： cadmium (Cd)     low-Cd cultivar     pakchoi (Brassica chinensis L.)    

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High cadmium pollution risk on vegetable amaranth and a selection for pollution-safe cultivars to lower the risk

Yihui ZHOU, Meng XUE, Zhongyi YANG, Yulian GONG, Jiangang YUAN, Chunyan ZHOU, Baifei HUANG

Frontiers of Environmental Science & Engineering 2013, Volume 7, Issue 2,   Pages 219-230 doi: 10.1007/s11783-012-0469-9

Abstract: pot experiment was carried out by growing 29 different genotypes ( spp.) of vegetable amaranth under lowCd concentrations in edible parts of the tested genotypes grown under low- and middle-Cd levels wereNan), a selected typical pollution-safe cultivar (Cd-PSC), and cv. Pennongjianyexian (cv.Pen), a selected typical non-Cd-PSC, under different Cd exposure conditions were compared.Therefore, adopting Cd-PSC strategy would help reducing the risk of Cd pollution in amaranth.

Keywords： Amaranth     Cadmium (Cd)     Cd accumulation     pollution-safe cultivar (PSC)     Cd chemical forms     health risk    

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Identification of pakchoi cultivars with low cadmium accumulation and soil factors that affect their

Lin WANG,Yingming XU,Yuebing SUN,Xuefeng LIANG,Dasong LIN

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 6,   Pages 877-887 doi: 10.1007/s11783-014-0676-7

Abstract: The selection and use of low-Cd-accumulating cultivar (LCAC) has been proposed as one of the promisingResults of the pot culture experiment showed that shoot Cd concentrations under the three Cd treatmentslower than 0.2 mg·kg under low Cd treatment and high Cd exposure did not affect the biomass of theirThe plot experiment further confirmed the consistency and genotypic stability of the low-Cd-accumulatingThe total Cd accumulation and translocation rates were lower in the LCACs than in the high-Cd cultivar

Keywords： cadmium contamination     low-cadmium-accumulating cultivar (LCAC)     genotype variation     soil factor     translocation    

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Preclinical characterization and comparison between CD3/CD19 bispecific and novel CD3/CD19/CD20 trispecific

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 139-149 doi: 10.1007/s11684-021-0835-8

Abstract: The CD19-targeting bispecific T-cell engager blinatumomab has shown remarkable efficacy in patients withHowever, several studies showed that blinatumomab has a short plasma half-life due to its low molecularBlinatumomab and A-319 are CD3/CD19 bispecific antibodies with different molecular sizes and structures, and A-2019 is a novel CD3/CD19/CD20 trispecific antibody with an additional anti-CD20 function.in cells missing CD19, suggesting its potential function against CD19 weak or negative CD20 positive

Keywords： B-cell acute lymphoblastic leukemia     bispecific antibody     trispecific antibody     CD19     CD20    

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Clinical significance of CD34+CD117dim/CD34+CD117bri myeloblast-associated

Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 608-620 doi: 10.1007/s11684-021-0836-7

Abstract: Two leukemic myeloblast populations (CD34 CD117 and CD34 CD117 ) were previously identified in t(8;21Here, we examined the impact of CD34 CD117 /CD34 CD117 myeloblast-associated gene expression on t(8;The mRNA expression levels of CD34 CD117 -associated genes ( , , and ) and CD34 CD117 -associated genesUnivariate analysis revealed that CD19, CD34 CD117 proportion, mutation, minimal residual diseaseIdentifying the clinical relevance of CD34 CD117 /CD34 CD117 myeloblast-associated gene expression may

Keywords： t(8     21)(q22     q22) AML     CD34+CD117dim/ CD34+CD117bri cell population    

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Correlative investigation of copper/low-density polyethylene nanocomposite on the endometrial angiogenesis

LI Jianxiong, LIU Zilong, DUAN Yonggang, YU Jing, ZHU Changhong, LI Shuang, XIE Changsheng

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 401-404 doi: 10.1007/s11684-007-0078-3

Abstract: The purpose of this study was to investigate the effects of copper/low-density polyethylene nanocompositeThe levels of angiopoietin-2 (Ang-2), its receptor (Tie-2) and CD34 of the rats endometria in each group

Keywords： significant difference     female     endometrial angiogenesis     nano-Cu/LDPE     CD34    

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Cultivars and oil extraction techniques affect Cd/Pb contents and health risks in oil of rapeseed grownon Cd/Pb-contaminated farmland

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 7, doi: 10.1007/s11783-023-1687-z

Abstract:

● Organic solvent extracted fewer Cd/Pb in rapeseed oil than physical

Keywords： Rapeseed oil     Oil extraction technologies     Human health risk assessment     Cd/Pb-contaminated farmland    

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Growth responses of the newly-discovered Cd-hyperaccumulator Rorippa globosa and its accumulation characteristicsof Cd and As under joint stress of Cd and As

SUN Yuebing, ZHOU Qixing, WEI Shuhe, REN Liping

Frontiers of Environmental Science & Engineering 2007, Volume 1, Issue 1,   Pages 107-113 doi: 10.1007/s11783-007-0020-6

Abstract: under joint stress of Cd and As.The results showed that Cd and As had an antagonistic effect on enhancing the growth of plants and Cduptake and accumulation under the low concentration Cd and As treatments.level under single Cd pollution.from a high concentration of Cd and As.

Keywords： synergic adverse     stress     present study     potential     weight    

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Celecoxib in combination with retinoid CD437 inhibits melanoma A375 cell

Jianwen REN, Zhenhui PENG, Birong GUO, Min PAN

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 108-112 doi: 10.1007/s11684-009-0015-8

Abstract: of celecoxib, synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid (CD437Both celecoxib and CD437 could inhibit the growth of human malignant melanoma A375 cells in a dose-dependentCelecoxib in combination with CD437 could significantly enhance the effects of inhibiting proliferationCD437 could inhibit the growth of human malignant melanoma A375 cells by inducing apoptosis and G /GCelecoxib exhibited additive effects with CD437 on retarding the growth and inducing apoptosis of human

Keywords： celecoxib     CD437     melanoma A375 cell     apoptosis     cycle arrest    

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Tumor-derived exosomes induce initial activation by exosomal CD19 antigen but impair the function ofCD19-specific CAR T-cells via TGF-β signaling

Frontiers of Medicine 2024, Volume 18, Issue 1,   Pages 128-146 doi: 10.1007/s11684-023-1010-1

Abstract: Tumor-derived exosomes induce initial activation by exosomal CD19 antigen but impair the function ofCD19-specific CAR T-cells via TGF-β signaling

Keywords： exosomes induce activation     impair function CD19     exosomal CD19 antigen    

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Changes of phenotype and function of human CD4 CD25 T cells induced by transfection of Foxp3

WU Kui, BI Yutian, WANG Yaoli, WANG Changzheng

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 366-369 doi: 10.1007/s11684-008-0070-6

Abstract: Virus-containing supernatant was applied to differentiate CD4CD25 T cells.The effect of transfected CD4 T cells on the proliferation and cytokine production of CD4CD25 T cellsexpressions of CD25 and CTLA-4, but down-regulated CD127 expression.Transfected T cells inhibited the proliferation of CD4CD25 T cells.This suggested a key role of Foxp3 in the generation of CD4CD25 regulatory T cells.
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Response of indigenous Cd-tolerant electrochemically active bacteria in MECs toward exotic Cr(VI) based

Xia Hou, Liping Huang, Peng Zhou, Hua Xue, Ning Li

Frontiers of Environmental Science & Engineering 2018, Volume 12, Issue 4, doi: 10.1007/s11783-018-1057-4

Abstract:

Cell membrane of indigenous Cd-tolerant EAB harbored more cadmium

Indigenous Cd-tolerant EAB cytoplasm located

Simultaneously quantitatively imaging Cd(II)

Keywords： Microbial electrolysis cell     Electrochemically active bacteria     Cd-tolerant bacteria     Cd(II) and Cr(VI)    

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Downregulation effects of beta-elemene on the levels of plasma endotoxin, serum TNF-alpha, and hepatic CD14

Jianguo LIU, Zhe ZHANG, Jiechang GAO, Jiwen XIE, Lin YANG, Shenjun HU

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 101-105 doi: 10.1007/s11684-011-0111-4

Abstract: CD14 expression in rat livers was measured by immunohistochemistry and Western blot.that β-elemene can downregulate the levels of plasma endotoxins, serum TNF-α, and hepatic CD14

Keywords： liver fibrosis     beta-elemene     endotoxin     CD14    

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CD47 blockade improves the therapeutic effect of osimertinib in non-small cell lung cancer

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 105-118 doi: 10.1007/s11684-022-0934-1

Abstract: In this study, OSI induced higher CD47 expression, an important anti-phagocytic immune checkpoint, viaThe combination treatment of OSI and the anti-CD47 antibody exhibited dramatically increasing phagocytosisConsistently, the enhanced phagocytosis index from combination treatment was reversed in CD47 knockoutMeanwhile, combining the anti-CD47 antibody significantly augmented the anticancer effect of OSI in HCC827antibody with OSI as a new strategy to enhance the anticancer efficacy in EGFR-mutant NSCLC with CD47

Keywords： osimertinib     anti-CD47 antibody     combination strategy     ADCP     EGFR    

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Moderate expression of CD39 in GPC3-CAR-T cells shows high efficacy against hepatocellular carcinoma

Frontiers of Medicine doi: 10.1007/s11684-024-1071-9

Abstract: CD39 serves as a crucial biomarker for neoantigen-specific CD8+ T cells and is associateddivision inhibitor-1 (mdivi-1), or knockdown CD39 through short hairpin RNA.antitumor activity, while high and low levels of CD39 led to an impaired cellular function.Methods modulating the proportion of CD39 intermediate (CD39int)-phenotype CAR-T cells suchas mdivi-1 and CD39 knockdown enhanced and impaired T cell function, respectively.

Keywords： CD39     CAR-T cells     mdivi-1     hepatocellular carcinoma     antitumor activity    

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Title Author Date Type Operation

Comparisons in subcellular and biochemical behaviors of cadmium between low-Cd and high-Cd accumulation

Meng XUE, Yihui ZHOU, Zhongyi YANG, Biyun LIN, Jiangang YUAN, Shanshan WU

Journal Article

High cadmium pollution risk on vegetable amaranth and a selection for pollution-safe cultivars to lower the risk

Yihui ZHOU, Meng XUE, Zhongyi YANG, Yulian GONG, Jiangang YUAN, Chunyan ZHOU, Baifei HUANG

Journal Article

Identification of pakchoi cultivars with low cadmium accumulation and soil factors that affect their

Lin WANG,Yingming XU,Yuebing SUN,Xuefeng LIANG,Dasong LIN

Journal Article

Preclinical characterization and comparison between CD3/CD19 bispecific and novel CD3/CD19/CD20 trispecific

Journal Article

Clinical significance of CD34+CD117dim/CD34+CD117bri myeloblast-associated

Xueping Li, Yuting Dai, Bing Chen, Jinyan Huang, Saijuan Chen, Lu Jiang

Journal Article

Correlative investigation of copper/low-density polyethylene nanocomposite on the endometrial angiogenesis

LI Jianxiong, LIU Zilong, DUAN Yonggang, YU Jing, ZHU Changhong, LI Shuang, XIE Changsheng

Journal Article

Cultivars and oil extraction techniques affect Cd/Pb contents and health risks in oil of rapeseed grownon Cd/Pb-contaminated farmland

Journal Article

Growth responses of the newly-discovered Cd-hyperaccumulator Rorippa globosa and its accumulation characteristicsof Cd and As under joint stress of Cd and As

SUN Yuebing, ZHOU Qixing, WEI Shuhe, REN Liping

Journal Article

Celecoxib in combination with retinoid CD437 inhibits melanoma A375 cell

Jianwen REN, Zhenhui PENG, Birong GUO, Min PAN

Journal Article

Tumor-derived exosomes induce initial activation by exosomal CD19 antigen but impair the function ofCD19-specific CAR T-cells via TGF-β signaling

Journal Article

Changes of phenotype and function of human CD4 CD25 T cells induced by transfection of Foxp3

WU Kui, BI Yutian, WANG Yaoli, WANG Changzheng

Journal Article

Response of indigenous Cd-tolerant electrochemically active bacteria in MECs toward exotic Cr(VI) based

Xia Hou, Liping Huang, Peng Zhou, Hua Xue, Ning Li

Journal Article

Downregulation effects of beta-elemene on the levels of plasma endotoxin, serum TNF-alpha, and hepatic CD14

Jianguo LIU, Zhe ZHANG, Jiechang GAO, Jiwen XIE, Lin YANG, Shenjun HU

Journal Article

CD47 blockade improves the therapeutic effect of osimertinib in non-small cell lung cancer

Journal Article

Moderate expression of CD39 in GPC3-CAR-T cells shows high efficacy against hepatocellular carcinoma

Journal Article