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Association of miRNA-122-binding site polymorphism at the interleukin-1 α gene and its interaction with

Du Yan, Han Xue, Pu Rui, Xie Jiaxin, Zhang Yuwei, Cao Guangwen

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 217-226 doi: 10.1007/s11684-014-0326-2

Abstract:

This study was designed to investigate the contribution of miRNA-122-binding site polymorphism at

Keywords： hepatocellular carcinoma (HCC)     interaction     miRNA-122-binding site     IL-1A     rs3783553     hepatitis B virus (    

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Chloride binding and time-dependent surface chloride content models for fly ash concrete

S. MUTHULINGAM,B. N. RAO

Frontiers of Structural and Civil Engineering 2016, Volume 10, Issue 1,   Pages 112-120 doi: 10.1007/s11709-015-0322-x

Abstract: fly ash concrete, namely: 1) surface chloride content under tidal exposure condition; and 2) chloride bindingFirst, inconsistencies in surface chloride content and chloride binding models reported in literatureSecondly, to avoid such inconsistencies, surface chloride content and chloride binding models for fly

Keywords： binding isotherms     chloride ingress     concrete     fly ash     surface chloride content    

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Influence of site conditions on seismic design parameters for foundations as determined via nonlinearsite response analysis

Muhammad Tariq A. CHAUDHARY

Frontiers of Structural and Civil Engineering 2021, Volume 15, Issue 1,   Pages 275-303 doi: 10.1007/s11709-021-0685-0

Abstract: Site conditions, including geotechnical properties and the geological setting, influence the near-surfaceparameters ( , , and ) was investigated for National Earthquake Hazards Reduction Program (NEHRP) siteclasses C and D, through 1D nonlinear seismic site response analysis.Predictive relationships for , , and were derived based on the 1D seismic site response analysis

Keywords： site effects     1D seismic site response analysis     sensitivity analysis     foundations     shear wave velocity     soil    

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MiRNA-451 is a potential biomarker for estrogenicity in mouse uterus

Lingyan HOU, Yun LU, Ying LI, Li LI

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 1,   Pages 99-105 doi: 10.1007/s11783-013-0490-7

Abstract: MicroRNA (miRNA) is a class of regulatory gene, which has been shown to be a good biomarker for manyIn this study, two types of microarrays were used to test the 17β-estradiol (E2) induced miRNA expression

Keywords： estrogen     microRNA (miRNA)     microarray     biomarker    

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Simplified seismic scenario analysis of existing masonry buildings accounting for local site effects

Frontiers of Structural and Civil Engineering 2024, Volume 18, Issue 2,   Pages 309-318 doi: 10.1007/s11709-024-0982-5

Abstract: Damage scenarios were generated for all soil classes, different moment magnitudes, and source-to-siteConsequently, damage distributions estimated under nine different scenarios with/without site effectsthe rapid seismic evaluation procedure by including geo-hazard-based assessment, the importance of siteThe proposed framework integrating field data and local site effects is believed to advance the current

Keywords： masonry buildings     seismic vulnerability assessment     cultural heritage     local site effect    

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Proteomics study of Mycoplasma pneumoniae pneumonia reveals the Fc fragment of the IgG-binding protein

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 378-388 doi: 10.1007/s11684-021-0840-y

Abstract: The Fc fragment of the IgG-binding protein (FCGBP) was identified as the most promising indicator of

Keywords： severe Mycoplasma pneumoniae pneumonia     children     proteomics     Fc fragment of the IgG-binding protein    

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reduces IgE binding ability of allergenic egg white proteins

Sen LI, Marina OFFENGENDEN, Michael G. GÄNZLE, Jianping WU

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 3,   Pages 373-381 doi: 10.15302/J-FASE-2018210

Abstract: objective of this study was to investigate the effect of Aspergillus oryzae cultivation on IgE bindingAdding mycelium of A. oryzae ATCC 1011 and 16868 substantially reduced the IgE binding abilityThe binding capacity of egg white proteins to IgE in plasma from four egg allergy patients was almostTherefore, the reduction of IgE binding ability of egg white proteins during A. oryzae treatment

Keywords： Aspergillus oryzae     egg allergy     egg white proteins     IgE-binding ability     ovomucoid    

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Development and application of an off-site maintenance system in the petrochemical industry

Ruisheng YONG, Yanbing YE, Hanbin LUO, Lieyun DING

Frontiers of Engineering Management 2017, Volume 4, Issue 2,   Pages 111-126 doi: 10.15302/J-FEM-2017027

Abstract: On-site maintenance (ONSM) is critical to ensuring the safety of equipment in the petrochemical industryTo reduce congestion and exposure to hazards during on-site operations and thereby reduce the probabilityof accidents, off-site maintenance (OFSM) is proposed based on Energy Release Theory (ERT).

Keywords： on-site maintenance     petrochemical industry     safety     off-site maintenance system    

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Quantitative characterization of Cu binding potential of dissolved organic matter (DOM) in sediment from

Yuan ZHANG,Yan ZHANG,Tao YU

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 5,   Pages 666-674 doi: 10.1007/s11783-013-0608-y

Abstract: sediment samples were collected from various part of Taihu Lake to explore the spatial difference in the bindingThe ISE results showed that the exogenous DOM had higher binding ability than endogenous DOM, and DOMderived from aquatic macrophytes had a higher binding ability than that derived from algae.

Keywords： binding ability     dissolved organic matters     fluorescence quenching     complex capacity     Taihu Lake    

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Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block

Xiaoling Wang,Yun Tan,Yizhen Li,Jingming Li,Wen Jin,Kankan Wang

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 420-429 doi: 10.1007/s11684-016-0478-3

Abstract: Furthermore, all-trans retinoic acid treatment induced CDKN2C expression by releasing the PML/RARα binding

Keywords： CDKN2C     acute promyelocytic leukemia     cell cycle arrest     differentiation    

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MiR-516a-3p is a Novel Mediator of Hepatocellular Carcinoma Oncogenic Activity and Cellular Metabolism

Tao Rui,Xueyou Zhang,Shi Feng,Haitao Huang,Shaowei Zhan,Haiyang Xie,Lin Zhou,Shusen Zheng,Qi Ling,

Engineering 2022, Volume 16, Issue 9,   Pages 162-175 doi: 10.1016/j.eng.2021.07.020

Abstract: In the current study, we aim to explore the role of miR-516a-3p—an identical mature microRNA (miRNA

Keywords： Hepatocellular carcinoma     miRNA cluster     Exosome     Multi-omics    

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Autophagy in hepatic progenitor cells modulates exosomal miRNAs to inhibit liver fibrosis in schistosomiasis

Frontiers of Medicine 2024, Volume 18, Issue 3,   Pages 538-557 doi: 10.1007/s11684-024-1079-1

Abstract: HPC-secreted extracellular vehicles (EVs) were further isolated and studied by miRNA sequencing. miR-the altered autophagy process upon HPC activation may prevent liver fibrosis by modulating exosomal miRNA

Keywords： schistosomiasis     hepatic progenitor cell     autophagy     extracellular vesicle     fibrosis     miRNA    

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Inflammation and liver tumorigenesis

Beicheng Sun, Michael Karin

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 242-254 doi: 10.1007/s11684-013-0256-4

Abstract:

Inflammation has been considered as one of the hallmarks of cancer, and chronic hepatitis is a major cause of liver cancer. This review will focus on the pathogenic role of inflammation in hepatocarcinogenesis and will discuss recent advances in understanding the chronic hepatitis-liver cancer link based on hot spots in liver cancer research, including cellular interaction, cytokines, microRNA and stem cells. All of these mechanisms should be taken into consideration because they are crucial for the development of more efficacious therapeutic strategies for preventing and treating human chronic hepatitis and hepatocellular carcinoma.

Keywords： hepatocellular carcinoma     hepatitis     cytokine     stem cell     miRNA    

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An integrated approach to site-specific management zone delineation

Yuxin MIAO, David J. MULLA, Pierre C. ROBERT

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 4,   Pages 432-441 doi: 10.15302/J-FASE-2018230

Abstract: The objective of this study is to propose an integrated approach to delineating site-specific MZ usingyears of nitrogen (N) rate experiments were conducted in Field B to evaluate the delineated MZs for site-specificIt also has the potential for site-specific N management for improved economic returns.

Keywords： economically optimum nitrogen rate     fuzzy cluster analysis     precision nitrogen management     site-specific    

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Vacuum promotes metabolic shifts and increases biogenic hydrogen production in dark fermentation systems

Haifa RAJHI,Daniel PUYOL,Mirna C. MARTÍNEZ,Emiliano E. DÍAZ,José L. SANZ

Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 3,   Pages 513-521 doi: 10.1007/s11783-015-0777-y

Abstract: The successful operation of any type of hydrogen-producing bioreactor depends on the performance of the microorganisms present in the system. Both substrate and partial gas pressures are crucial factors affecting dark fermentation metabolic pathways. The main objective of this study was to evaluate the impact of both factors on hydrogen production using anaerobic granular sludge as inoculum and, secondly, to study the metabolic shifts of an anaerobic community subjected to low partial gas pressures. With this goal in mind, seven different wastewater (four synthetic media, two industrial wastewater, and one domestic effluent) and the effect of applying vacuum on the systems were analyzed. The application of vacuum promoted an increase in the diversity of hydrogen-producing bacteria, such as , and promoted the dominance of acetoclastic- over hydrogenotrophic methanogens. The application of different media promoted a wide variety of metabolic pathways. Nevertheless, reduction of the hydrogen partial pressure by application of vacuum lead to further oxidation of reaction intermediates irrespective of the medium used, which resulted in higher hydrogen and methane production, and improved the COD removal. Interestingly, vacuum greatly promoted biogenic hydrogen production from a real wastewater, which opens possibilities for future application of dark fermentation systems to enhance biohydrogen yields.

Keywords： dark fermentation     biohydrogen     wastewaters     vacuum    

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Title Author Date Type Operation

Association of miRNA-122-binding site polymorphism at the interleukin-1 α gene and its interaction with

Du Yan, Han Xue, Pu Rui, Xie Jiaxin, Zhang Yuwei, Cao Guangwen

Journal Article

Chloride binding and time-dependent surface chloride content models for fly ash concrete

S. MUTHULINGAM,B. N. RAO

Journal Article

Influence of site conditions on seismic design parameters for foundations as determined via nonlinearsite response analysis

Muhammad Tariq A. CHAUDHARY

Journal Article

MiRNA-451 is a potential biomarker for estrogenicity in mouse uterus

Lingyan HOU, Yun LU, Ying LI, Li LI

Journal Article

Simplified seismic scenario analysis of existing masonry buildings accounting for local site effects

Journal Article

Proteomics study of Mycoplasma pneumoniae pneumonia reveals the Fc fragment of the IgG-binding protein

Journal Article

reduces IgE binding ability of allergenic egg white proteins

Sen LI, Marina OFFENGENDEN, Michael G. GÄNZLE, Jianping WU

Journal Article

Development and application of an off-site maintenance system in the petrochemical industry

Ruisheng YONG, Yanbing YE, Hanbin LUO, Lieyun DING

Journal Article

Quantitative characterization of Cu binding potential of dissolved organic matter (DOM) in sediment from

Yuan ZHANG,Yan ZHANG,Tao YU

Journal Article

Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block

Xiaoling Wang,Yun Tan,Yizhen Li,Jingming Li,Wen Jin,Kankan Wang

Journal Article

MiR-516a-3p is a Novel Mediator of Hepatocellular Carcinoma Oncogenic Activity and Cellular Metabolism

Tao Rui,Xueyou Zhang,Shi Feng,Haitao Huang,Shaowei Zhan,Haiyang Xie,Lin Zhou,Shusen Zheng,Qi Ling,

Journal Article

Autophagy in hepatic progenitor cells modulates exosomal miRNAs to inhibit liver fibrosis in schistosomiasis

Journal Article

Inflammation and liver tumorigenesis

Beicheng Sun, Michael Karin

Journal Article

An integrated approach to site-specific management zone delineation

Yuxin MIAO, David J. MULLA, Pierre C. ROBERT

Journal Article

Vacuum promotes metabolic shifts and increases biogenic hydrogen production in dark fermentation systems

Haifa RAJHI,Daniel PUYOL,Mirna C. MARTÍNEZ,Emiliano E. DÍAZ,José L. SANZ

Journal Article