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Traditional Chinese medicine in the new century

Jianxiang Liu, Zhu Chen

Frontiers of Medicine 2011, Volume 5, Issue 2, Pages 111-114 doi: 10.1007/s11684-011-0125-y

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Holistic integrative medicine: toward a new era of medical advancement

Daiming Fan

Frontiers of Medicine 2017, Volume 11, Issue 1, Pages 152-159 doi: 10.1007/s11684-017-0499-6

Abstract:

Medicine has encountered unprecedented problems associated with changes in nature, society, and environment, as well as with new human quests for survival, longevity, and health.In the meantime, the development of medicine is facing challenges that resulted from the over-divisionTo construct a new medical system that is more suitable for human health and disease treatment, holisticHIM is the inevitable and necessary direction for the future development of medicine.

Keywords： holistic integrative medicine precision medicine general practice medicine

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Development Strategy of “New Medicine” Under the Background of Healthy China

He Ke, Wang Ling

Strategic Study of Chinese Academy of Engineering 2019, Volume 21, Issue 2, Pages 98-102 doi: 10.15302/J-SSCAE-2019.02.007

Abstract:

This paper starts with the connotation of “new medicine”under the background of Healthy China, focuses on the “new medicine” talent training system, and illustrates the necessity and urgency of developing “new medicine” from three aspectsThis paper further elaborates the basic strategy of “1234” for developing “new medicinethe “new quality” of “two types of balance”, promoting the “new system&

Keywords： healthy China new medicine interdisciplinary integration

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ECRG4: a new potential target in precision medicine

Xin Qin, Ping Zhang

Frontiers of Medicine 2019, Volume 13, Issue 5, Pages 540-546 doi: 10.1007/s11684-018-0637-9

Abstract: Given the rapid development in precision medicine, tremendous efforts have been devoted to discoveringnew biomarkers for disease diagnosis and treatment.Esophageal cancer-related gene-4 ( ), which is initially known as a new candidate tumor suppressor genemembrane upon activation and detected in liquid biopsy, thus offering considerable potential in precision medicineThe future perspectives of ECRG4 as a potential molecular marker in precision medicine are also discussed

Keywords： ECRG4 tumor suppressor gene sentinel molecule precision medicine cell senescence epithelium homeostasis

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Prospect in Creating New Drugs from Chinese Herbal Medicine

Yu Dequan

Strategic Study of Chinese Academy of Engineering 1999, Volume 1, Issue 2, Pages 87-90

Abstract: has proved to be one of the most effective ways for the development of new drugs.This paper describes the progress in creating new drugs based on researches on natural products chemistryfor many years and some interesting new trends emerging from recent literature.study of the chemical constituents of composite Chinese medicine.It should be emphasized that the investigation of bioactive compounds for creating new drugs is the major

Keywords： natural product research creating new drug chemical constituent of Chinese herbal medicine modem spectroscopic

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Individualized medicine, health medicine, and constitutional theory in Chinese medicine

Qi Wang

Frontiers of Medicine 2012, Volume 6, Issue 1, Pages 1-7 doi: 10.1007/s11684-012-0173-y

Abstract: Individualized treatment in modern medicine is mainly established based on individual genome informationChinese constitutional theory developed in the 1970s expresses the principle behind Chinese health medicineIt promotes the study of the relationship of each constitution to diseases and Chinese medicine preparationBy combining the developments in modern biotechnology, new diagnostic techniques and treatment modelstreatment and health medicine for the international medical community.

Keywords： individualized medicine health medicine constitutional theory in Chinese medicine

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Development Strategy of Chinese and Western Integrative Medicine Under New Circumstances

Wang Conghui, Feng Zhe, Yin Zhiwei, Li Shuang, Chen Xiangmei

Strategic Study of Chinese Academy of Engineering 2021, Volume 23, Issue 2, Pages 169-174 doi: 10.15302/J-SSCAE-2021.02.016

Abstract: The Chinese and western integrative medicine, a unique medical model in China, has played an importantreview and questionnaire survey, and summarize the key roles of this integrative medicine in the preventionSubsequently, we analyze the weaknesses of the integrative medicine in terms of medical resources, clinicalresearch, and internationalization, and propose the construction goals for this discipline under the newand a world-leading role in the integration of Chinese traditional medicine with western medicine.

Keywords： Chinese and western integrative medicine evidence-based medicine evaluation system talent training

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Thinking About Establishing New Medicine

Ma Ainai,Zhao Shaoqui

Strategic Study of Chinese Academy of Engineering 2007, Volume 9, Issue 10, Pages 19-23

Abstract: There are many achievements in the medicine and cure of illness. So Western medicine has puzzled itself about how to stick up for whole human body.There are also and many achievements in the medicine and cure.nbsp;and achieve both of them with a uniform to systemic theory" , advance to establish a newmedicine, that is "Human Body Ecological Medicine" .

Keywords： open complex giant system human body ecosystem human body information system human body ecological medicine

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Thinking and practice of accelerating transformation of traditional Chinese medicine from experiencemedicine to evidence-based medicine

Baoyan Liu, Yanhong Zhang, Jingqing Hu, Liyun He, Xuezhong Zhou

Frontiers of Medicine 2011, Volume 5, Issue 2, Pages 163-170 doi: 10.1007/s11684-011-0143-9

Abstract: in clinical practice, but without the benefit of undergoing the experimental medicine stage.medicine to Chinese medicine is appearing.The rapid transition and transformation from experience medicine to evidence-based medicine have becomeimportant content in the development of Chinese medicine., as well as transform and develop Chinese medicine from experience medicine to evidence-based medicine

Keywords： Chinese medicine experience medicine evidence-based medicine real world

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Clinical research of traditional Chinese medicine in big data era

Junhua Zhang,Boli Zhang

Frontiers of Medicine 2014, Volume 8, Issue 3, Pages 321-327 doi: 10.1007/s11684-014-0370-y

Abstract: Data-intensive scientific discovery based on big data, named “The Fourth Paradigm,” has become a newpreventive healthcare and symptom pattern differentiation for treatment in terms of traditional Chinese medicine

Keywords： big data traditional Chinese medicine clinical evaluation evidence based medicine

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Do not let precision medicine be kidnapped

Zhiping Yang

Frontiers of Medicine 2015, Volume 9, Issue 4, Pages 512-513 doi: 10.1007/s11684-015-0425-8

Abstract:

Obama’s precision medicine initiative made the medical community boil over after the initiativePrecision medicine has been advocated by the majority of scientists and doctors.This article does not oppose precision medicine.However, the incentive of vigorously promoting precision medicine at present is a concern.

Keywords： precision medicine personalized medicine genomics

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Patient-derived xenograft platform of OSCC: a renewable human bio-bank for preclinical cancer research and a new

Shuyang Sun,Zhiyuan Zhang

Frontiers of Medicine 2016, Volume 10, Issue 1, Pages 104-110 doi: 10.1007/s11684-016-0432-4

Abstract:

Advances in next-generation sequencing and bioinformatics have begun to reveal the complex genetic landscape in human cancer genomes, including oral squamous cell carcinoma (OSCC). Sophisticated preclinical models that fully represent intra- and inter-tumoral heterogeneity are required to understand the molecular diversity of cancer and achieve the goal of personalized therapies. Patient-derived xenograft (PDX) models generated from human tumor samples that can retain the histological and genetic features of their donor tumors have been shown to be the preferred preclinical tool in translational cancer research compared with other conventional preclinical models. Specifically, genetically well-defined PDX models can be applied to accelerate targeted antitumor drug development and biomarker discovery. Recently, we have successfully established and characterized an OSCC PDX panel as part of our tumor bio-bank for translational cancer research. In this paper, we discuss the establishment, characterization, and preclinical applications of the PDX models. In particular, we focus on the classification and applications of the PDX models based on validated annotations, including clinicopathological features, genomic profiles, and pharmacological testing information. We also explore the translational value of this well-annotated PDX panel in the development of co-clinical trials for patient stratification and treatment optimization in the near future. Although various limitations still exist, this preclinical approach should be further tested and improved.

Keywords： patient-derived xenograft models personalized medicine co-clinical trial patient stratification oral

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Research on Origin of Traditional Chinese Medicine

Fu Youfeng

Strategic Study of Chinese Academy of Engineering 2006, Volume 8, Issue 9, Pages 1-12

Abstract: , the author has explored the relationship between epidemic disease (especially bubonic plague) and medicineFrom the point of view that medicine comes of epidemic disease, the author has conducted research onrich resources of Chinese cultural relics, ancient writing and medical literature on medicine historyincluding the difference between ancient name and modem name of disease, difference between TCM and Western medicinepromotion of TCM achievement on epidemic disease and for the research on combination of TCM and Western medicine

Keywords： world medicine history history of TCM medicine origin plague cholera smallpox comparative medicine

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Practices, challenges, and opportunities: HIV/AIDS treatment with traditional Chinese medicine in China

Jian Wang, Wen Zou

Frontiers of Medicine 2011, Volume 5, Issue 2, Pages 123-126 doi: 10.1007/s11684-011-0124-z

Abstract: Traditional Chinese medicine (TCM) has become widely used in the treatment of acquired immune deficiency

Keywords： HIV/AIDS traditional Chinese medicine

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The Origin of Traditional Chinese Medicine and Thinking on Chinese Medicine Development

Wang Wenkui,Wang Feng,Wang Ling

Strategic Study of Chinese Academy of Engineering 2006, Volume 8, Issue 4, Pages 1-11

Abstract:

A principle of “Adopting the advanced part of Western medicine to serve the TCM”should be adhered to for the traditional Chinese medicine.It is necessary not only prepare the medicine in advance according to the predicted disease of the year

Keywords： traditional Chinese medicine (TCM) development course & status of TCM adopting the advanced part ofwestern medicine to serve the TCM the dose type of traditional Chinese medicine