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Traditional Chinese medicine in the new century
Jianxiang Liu, Zhu Chen
Frontiers of Medicine 2011, Volume 5, Issue 2, Pages 111-114 doi: 10.1007/s11684-011-0125-y
Holistic integrative medicine: toward a new era of medical advancement
Daiming Fan
Frontiers of Medicine 2017, Volume 11, Issue 1, Pages 152-159 doi: 10.1007/s11684-017-0499-6
Medicine has encountered unprecedented problems associated with changes in nature, society, and environment, as well as with new human quests for survival, longevity, and health.In the meantime, the development of medicine is facing challenges that resulted from the over-divisionTo construct a new medical system that is more suitable for human health and disease treatment, holisticHIM is the inevitable and necessary direction for the future development of medicine.
Keywords: holistic integrative medicine precision medicine general practice medicine
Development Strategy of “New Medicine” Under the Background of Healthy China
He Ke, Wang Ling
Strategic Study of CAE 2019, Volume 21, Issue 2, Pages 98-102 doi: 10.15302/J-SSCAE-2019.02.007
This paper starts with the connotation of “new medicine”under the background of Healthy China, focuses on the “new medicine” talent training system, and illustrates the necessity and urgency of developing “new medicine” from three aspectsThis paper further elaborates the basic strategy of “1234” for developing “new medicinethe “new quality” of “two types of balance”, promoting the “new system&
Keywords: healthy China new medicine interdisciplinary integration
ECRG4: a new potential target in precision medicine
Xin Qin, Ping Zhang
Frontiers of Medicine 2019, Volume 13, Issue 5, Pages 540-546 doi: 10.1007/s11684-018-0637-9
Keywords: ECRG4 tumor suppressor gene sentinel molecule precision medicine cell senescence epithelium homeostasis
Prospect in Creating New Drugs from Chinese Herbal Medicine
Yu Dequan
Strategic Study of CAE 1999, Volume 1, Issue 2, Pages 87-90
Keywords: natural product research creating new drug chemical constituent of Chinese herbal medicine modem spectroscopic
Individualized medicine, health medicine, and constitutional theory in Chinese medicine
Qi Wang
Frontiers of Medicine 2012, Volume 6, Issue 1, Pages 1-7 doi: 10.1007/s11684-012-0173-y
Keywords: individualized medicine health medicine constitutional theory in Chinese medicine
Development Strategy of Traditional Chinese Medicine in the New Era
Xue Xiaojuan, Liu Cai , Wang Yimin , Sun Xiaobo , Cheng Yiyu , Hu Jingqing ,Tian Jinzhou , Wang Qi , Zhang Boli
Strategic Study of CAE 2023, Volume 25, Issue 5, Pages 11-20 doi: 10.15302/J-SSCAE-2023.05.007
Traditional Chinese medicine (TCM) develops rapidly in recent years inChina; meanwhile, it faces new challenges and shoulders new historical missions.TCM should be promoted to realize the integration of TCM with international traditional and modern medicine
Keywords: theoretical research of traditional Chinese medicine clinical advantage evaluation development andutilization of traditional Chinese medicine resources intelligent manufacturing of Chinese medicine globalization of traditional Chinese medicine
Development Strategy of Chinese and Western Integrative Medicine Under New Circumstances
Wang Conghui, Feng Zhe, Yin Zhiwei, Li Shuang, Chen Xiangmei
Strategic Study of CAE 2021, Volume 23, Issue 2, Pages 169-174 doi: 10.15302/J-SSCAE-2021.02.016
Keywords: Chinese and western integrative medicine evidence-based medicine evaluation system talent training
Thinking About Establishing New Medicine
Ma Ainai,Zhao Shaoqui
Strategic Study of CAE 2007, Volume 9, Issue 10, Pages 19-23
Keywords: open complex giant system human body ecosystem human body information system human body ecological medicine
Baoyan Liu, Yanhong Zhang, Jingqing Hu, Liyun He, Xuezhong Zhou
Frontiers of Medicine 2011, Volume 5, Issue 2, Pages 163-170 doi: 10.1007/s11684-011-0143-9
Keywords: Chinese medicine experience medicine evidence-based medicine real world
Clinical research of traditional Chinese medicine in big data era
Junhua Zhang,Boli Zhang
Frontiers of Medicine 2014, Volume 8, Issue 3, Pages 321-327 doi: 10.1007/s11684-014-0370-y
Keywords: big data traditional Chinese medicine clinical evaluation evidence based medicine
Research on Origin of Traditional Chinese Medicine
Fu Youfeng
Strategic Study of CAE 2006, Volume 8, Issue 9, Pages 1-12
Keywords: world medicine history history of TCM medicine origin plague cholera smallpox comparative medicine
Jian Wang, Wen Zou
Frontiers of Medicine 2011, Volume 5, Issue 2, Pages 123-126 doi: 10.1007/s11684-011-0124-z
Keywords: HIV/AIDS traditional Chinese medicine
Shuyang Sun,Zhiyuan Zhang
Frontiers of Medicine 2016, Volume 10, Issue 1, Pages 104-110 doi: 10.1007/s11684-016-0432-4
Advances in next-generation sequencing and bioinformatics have begun to reveal the complex genetic landscape in human cancer genomes, including oral squamous cell carcinoma (OSCC). Sophisticated preclinical models that fully represent intra- and inter-tumoral heterogeneity are required to understand the molecular diversity of cancer and achieve the goal of personalized therapies. Patient-derived xenograft (PDX) models generated from human tumor samples that can retain the histological and genetic features of their donor tumors have been shown to be the preferred preclinical tool in translational cancer research compared with other conventional preclinical models. Specifically, genetically well-defined PDX models can be applied to accelerate targeted antitumor drug development and biomarker discovery. Recently, we have successfully established and characterized an OSCC PDX panel as part of our tumor bio-bank for translational cancer research. In this paper, we discuss the establishment, characterization, and preclinical applications of the PDX models. In particular, we focus on the classification and applications of the PDX models based on validated annotations, including clinicopathological features, genomic profiles, and pharmacological testing information. We also explore the translational value of this well-annotated PDX panel in the development of co-clinical trials for patient stratification and treatment optimization in the near future. Although various limitations still exist, this preclinical approach should be further tested and improved.
Keywords: patient-derived xenograft models personalized medicine co-clinical trial patient stratification oral
Do not let precision medicine be kidnapped
Zhiping Yang
Frontiers of Medicine 2015, Volume 9, Issue 4, Pages 512-513 doi: 10.1007/s11684-015-0425-8
Obama’s precision medicine initiative made the medical community boil over after the initiativePrecision medicine has been advocated by the majority of scientists and doctors.This article does not oppose precision medicine.However, the incentive of vigorously promoting precision medicine at present is a concern.
Keywords: precision medicine personalized medicine genomics
Title Author Date Type Operation
Development Strategy of “New Medicine” Under the Background of Healthy China
He Ke, Wang Ling
Journal Article
Individualized medicine, health medicine, and constitutional theory in Chinese medicine
Qi Wang
Journal Article
Development Strategy of Traditional Chinese Medicine in the New Era
Xue Xiaojuan, Liu Cai , Wang Yimin , Sun Xiaobo , Cheng Yiyu , Hu Jingqing ,Tian Jinzhou , Wang Qi , Zhang Boli
Journal Article
Development Strategy of Chinese and Western Integrative Medicine Under New Circumstances
Wang Conghui, Feng Zhe, Yin Zhiwei, Li Shuang, Chen Xiangmei
Journal Article
Thinking and practice of accelerating transformation of traditional Chinese medicine from experiencemedicine to evidence-based medicine
Baoyan Liu, Yanhong Zhang, Jingqing Hu, Liyun He, Xuezhong Zhou
Journal Article
Clinical research of traditional Chinese medicine in big data era
Junhua Zhang,Boli Zhang
Journal Article
Practices, challenges, and opportunities: HIV/AIDS treatment with traditional Chinese medicine in China
Jian Wang, Wen Zou
Journal Article
Patient-derived xenograft platform of OSCC: a renewable human bio-bank for preclinical cancer research and a new
Shuyang Sun,Zhiyuan Zhang
Journal Article