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《化学科学与工程前沿(英文)》 >> 2014年 第8卷 第1期 doi: 10.1007/s11705-014-1413-2

Fe3O4 encapsulated mesoporous silica nanospheres with tunable size and large void pore

1. Department of Chemical Engineering, Curtin University, Perth WA 6845, Australia; 2. School of Chemical Engineering, The University of Adelaide, SA5005, Australia

发布日期: 2014-03-05

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摘要

Magnetic Fe O and mesoporous silica core-shell nanospheres with tunable size from 110–800 nm were synthesized via a one step self-assembly method. The morphological, structural, textural, and magnetic properties were well-characterized by scanning electron microscopy, transmission electron microscopy, X-ray diffraction, N adsorption-desorption and magnetometer. These nanocomposites, which possess high surface area, large pore volume and well-defined pore size, exhibit two dimensional hexagonal ( 6mm) mesostructures. Interestingly, magnetic core and mesoporous silica shell nanocomposites with large void pore (20 nm) on the shell were generated by increasing the ratio of ethanol/water. Additionally, the obtained nanocomposites combined magnetization response and large void pore, implying the possibility of applications in drug/gene targeting delivery. The cell internalization capacity of NH -functionalized nanocomposites in the case of cancer cells (HeLa cells) was exemplified to demonstrate their nano-medicine application.

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