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2015年 第9卷 第4期

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《化学科学与工程前沿（英文）》 >> 2015年 第9卷 第4期 doi: 10.1007/s11705-015-1536-0

SERS nanoprobes for bio-application

1. School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418, China.2. Department of Chemistry, State University of New York at Binghamton, Binghamton, NY 13902, USA

录用日期： 2015-10-26 发布日期： 2015-11-26
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The ability to tune the size, shape, composition and surface properties impart nanoparticles with the desired functions for bio-application. This article highlights some of the recent examples in the exploration of metal (e.g., gold and silver) nanoparticles, especially those with magnetic properties and bio-conjugated structures, as theranostic nanoprobes. Such nanoprobes exhibit tunable optical, spectroscopic, magnetic, and electrical properties for signal amplifications. Examples discussed in this article will focus on the nanoproble-enhanced colorimetric detection and surface enhanced Raman scattering (SERS) detection of biomarkers or biomolecules such as proteins and DNAs. The understanding of factors controlling the biomolecular interactions is essential for the design of SERS nanoprobes with theranostic functions.

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