Temperature segregation is non-uniform temperature distributionacross the uncompacted asphalt mat during paving operations and mayhave detrimental effects on the quality and performance of asphaltpavements. However, many research studies conducted across the UShave reported mixed observations regarding its effects on the initialquality and long-term performance of asphalt pavements.?The objectiveof this study was to determine the effects of the temperature segregationon the density and mechanical properties of Louisiana asphalt mixtures.Seven asphalt rehabilitation projects across Louisiana were selected.A multi-sensor infrared bar (Pave-IR) system and a hand-held portablethermal camera were used to measure the temperature of asphalt mats.Field core samples were collected from various areas with varyingseverity levels of temperature segregation and tested for the density,fracture resistance (J ) by semi-circular bending(SCB), rut depth by wheel tracking, and dynamic modulus (|E*|) byindirect tension (IDT) devices.?Two distinctive patterns of non-uniformtemperature distribution were observed: a cyclic and irregular temperaturesegregations. Laboratory test results showed that highly temperaturesegregated asphalt pavements (i.e., temperature differentials ≥41.7°C) can have significantly lower densities and the mechanicalproperties than the non-segregated area, especially when the temperaturedifferentials are measured at compaction.