Given the statistical gaps in material flow among provinces in China, a method was introduced to estimate regional physical imports and exports (RPIE), which includes international and interregional imports/exports. This method uses provincial monetary input-output tables (MIOT) and international trade statistics. A coefficient matrix representing correlations between monetary value and physical mass for years 2000–2009 was obtained based on a detailed commodity classification and 22 material production sectors in MIOT. With the coefficient matrix as reference, RPIE was measured. Pilot calculation of both regional physical trade balance and domestic material consumption, as well as a brief analysis of these methods, were conducted using 2002 data.