Identification of genome regions and important variations associated with expression level of

2015年第2卷第3期

摘要

关键词

相关研究

回顶部

《农业科学与工程前沿（英文）》 >> 2015年第2卷第3期 doi: 10.15302/J-FASE-2015057

Identification of genome regions and important variations associated with expression level of

1. Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education of China, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.2. The Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China

录用日期： 2015-07-06 发布日期： 2015-11-10

HTML16 PDF 5 收藏 0

摘要

Meat quality is one of the most important economic traits in pig breeding. It has been reported that the composition of type II muscle fibers is correlated with meat quality in pigs. Type II muscle fibers contain three isoforms, IIa, IIb and IIx, which contain specific myofibrillar proteins MYH2, MYH4 and MYH1, respectively. In this study, the expression levels of , , and genes in the Longissimus thoracis (LT) muscle were measured in 114 Yorkshire pigs. Further, the correlations between the expression level of genes and the meat quality traits of intramuscular fat, drip loss, water-holding capacity and postmortem pH values were analyzed. The results showed that the expression level of was positively correlated with the intramuscular fat ( = 0.20, <0.05). The expression levels of and were negatively correlated with the pH at 24 h post mortem (pH ; = －0.28, <0.01; = －0.25, <0.01, respectively). Besides, the 60K SNP chip was used for genotyping the individuals. Genome wide association analysis indicated that 15 SNPs were significantly associated with the expression levels of these three genes. The results indicated the expression levels of , and genes could be useful markers for improvement of meat quality in pigs.

关键词

pig ; IMF ; pH ; MYH1 ; MYH2 ; MYH4