2019年 第6卷 第2期
《农业科学与工程前沿（英文）》 >> 2019年 第6卷 第2期 doi: 10.15302/J-FASE-2018248
Regulation of NLR stability in plant immunity
. State Key Laboratory of Plant Cell and Chromosome Engineering/Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.. Eberly College of Science, The Pennsylvania State University, University Park, PA 16802, USA
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摘要
Plant nucleotide binding domain and leucine-rich repeat (NLR) receptors recognize pathogen effectors directly or indirectly and mediate innate immune responses. NLR-mediated immunity also has direct impacts on plant growth and development, as well as yield and survival. The levels of NLR proteins are therefore intricately controlled in plants to balance defense responses and other processes. In recent years, the ubiquitination-26S proteasome system and the HSP90 chaperones have emerged as having key functions in the regulation of NLR stability. The N-end rule pathway of protein degradation is also directly linked to NLR stability. Recent progress in the regulation of NLR stability and turnover is summarized here, focusing on the key components and pathways.
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