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2017年 第4卷 第3期

大纲

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《农业科学与工程前沿(英文)》 >> 2017年 第4卷 第3期 doi: 10.15302/J-FASE-2017152

Genome-wide association analysis reveals genetic loci and candidate genes associated with intramuscular fat in Duroc pigs

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. College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou 510642, China.. National Engineering Research Center for Breeding Swine Industry, Guangdong Wens Foodstuffs Group Co., Ltd., Yunfu 527400, China

录用日期 : 2017-04-06 发布日期 :2017-09-12

摘要

Intramuscular fat (IMF) is a major meat-quality trait in pigs. The content of IMF is directly associated with the taste and flavor of pork. As a complex trait, there could be multiple genes affecting IMF content in pork. Genome-wide association study is a powerful tool to detect genomic regions associated with phenotypic variations. The objectives of the present study were to identify or refine the positions of genomic regions affecting IMF, and to characterize candidate genes and pathways that may influence this trait. Of note, we identified a significant region in longissium dorsi muscle in a Duroc pig population for IMF content with PorcineSNP60 v2 BeadChip. This region spans 1.24 Mb on chromosome 8 and had been identified as a quantitative trait locus for IMF in Pietrain, Large White, Landrace, and Leicoma pigs. In this region, eight SNPs were significantly associated with IMF content. Three genes proximal to these significant SNPs were considered candidate genes, including , and . Our results confirm several previous findings and highlight several genes that may contribute to IMF variation in Duroc pigs.

关键词

Duroc pigs ; genome-wide association analysis ; intramuscular fat

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京公网安备 11010502051620号 京ICP备11030251号-2