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《中国工程科学》 >> 2015年 第17卷 第6期

复方口服避孕药对垂体-卵巢轴激素及卵泡发育的影响

华中科技大学同济医学院计划生育研究所,武汉 430030

收稿日期: 2015-06-16 发布日期: 2015-07-06 13:41:48.000

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摘要

复方口服避孕药(combined oral contraceptives,COCs)由外源性雌孕激素配伍而成,主要是通过高于生理水平的雌孕激素负反馈抑制垂体-卵巢轴,降低内源性促性腺激素和性激素的水平,影响卵泡的发育而避孕。但在周期性的COCs的无活性药间期(hormone-free interval, HFI)会有垂体-卵巢轴活性的恢复,其激素水平的变化及卵泡发育的情况与雌激素的剂量、孕激素的剂型、HFI的改变相关。

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