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期刊论文 4

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2023 2

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2011 1

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主–客体络合 1

分子识别纳米凝胶 1

分离 1

功能胶囊 1

微胶囊 1

控制释放 1

有机微污染物 1

泵送性能 1

海藻酸钙 1

肠靶向递送 1

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Encapsulation of polyethylene glycol in cellulose-based porous capsules for latent heat storage and light-to-thermal

《化学科学与工程前沿(英文)》 2023年 第17卷 第8期   页码 1038-1050 doi: 10.1007/s11705-022-2279-3

摘要: Phase change materials are potential candidates for the application of latent heat storage. Herein, we fabricated porous capsules as shape-stable materials from cellulose-based polyelectrolyte complex, which were first prepared using cellulose 6-(N-pyridinium)hexanoyl ester as the cationic polyelectrolyte and carboxymethyl cellulose as the anionic polyelectrolyte to encapsulate polyethylene glycol by the vacuum impregnation method. Furthermore, the multi-walled carbon nanotube or graphene oxide, which were separately composited into the polyelectrolytes complex capsules to enhance thermal conductivity and light-to-thermal conversion efficiency. These capsules owned a typical core–shell structure, with an extremely high polyethylene glycol loading up to 34.33 g∙g‒1. After loading of polyethylene glycol, the resulted cellulose-based composite phase change materials exhibited high thermal energy storage ability with the latent heat up to 142.2 J∙g‒1, which was 98.5% of pure polyethylene glycol. Further results showed that the composite phase change materials demonstrated good form-stable property and thermal stability. Moreover, studies involving light-to-thermal conversion determined that composite phase change materials exhibited outstanding light-to-thermal conversion performance. Considering their exceptional comprehensive features, innovative composite phase change materials generated from cellulose presented a highly interesting choice for thermal management and renewable thermal energy storage.

关键词: cellulose     polyelectrolytes     phase change materials     thermal energy storage     light-to-thermal conversion    

Ingestible wireless capsules for enhanced diagnostic inspection of gastrointestinal tract

Mahdi RASOULI, Andy Prima KENCANA, Van An HUYNH, Eng Kiat TING, Joshua Chong Yue LAI, Kai Juan WONG, Su Lim TAN, Soo Jay PHEE

《机械工程前沿(英文)》 2011年 第6卷 第1期   页码 40-44 doi: 10.1007/s11465-011-0204-4

摘要:

Wireless capsule endoscopy has become a common procedure for diagnostic inspection of gastrointestinal tract. This method offers a less-invasive alternative to traditional endoscopy by eliminating uncomfortable procedures of the traditional endoscopy. Moreover, it provides the opportunity for exploring inaccessible areas of the small intestine. Current capsule endoscopes, however, move by peristalsis and are not capable of detailed and on-demand inspection of desired locations. Here, we propose and develop two wireless endoscopes with maneuverable vision systems to enhance diagnosis of gastrointestinal disorders. The vision systems in these capsules are equipped with mechanical actuators to adjust the position of the camera. This may help to cover larger areas of the digestive tract and investigate desired locations. The preliminary experimental results showed that the developed platform could successfully communicate with the external control unit via human body and adjust the position of camera to limited degrees.

关键词: wireless capsule endoscopy     ingestible medical device     in-body medical device     miniature actuator     medical robot     medical imaging    

具有泵送控释性能的肠靶向Janus型双腔室海藻酸钙基微胶囊 Article

温霜, 巨晓洁, 刘文英, 刘玉琼, 蒲兴群, 刘壮, 汪伟, 谢锐, Yousef Faraj, 褚良银

《工程(英文)》 2023年 第24卷 第5期   页码 114-125 doi: 10.1016/j.eng.2022.05.021

摘要:

本文成功开发了一种具有泵送控释特性的θ形双腔室肠靶向海藻酸钙基微胶囊,囊壁为海藻酸钙-壳聚糖/精蛋白/二氧化硅(ACPSi)复合壳,为封装的药物在胃环境中提供了良好保护,实现药物的肠靶向释放。该θ形微胶囊由含药室和助推室两个腔室组成:含药室负载疏水药物吲哚美辛,其囊壁内嵌肠溶性
羟丙甲基纤维素邻苯二甲酸酯(HPMCP)微球,作为“微阀门”(micro-valves);助推室包封助推剂聚丙烯酸(PAA),在肠液环境中,PAA发生溶胀,可提高吲哚美辛释放速率。结果显示,载药的θ-ACPSi 微胶囊在模拟胃液(pH值为2.5)中,吲哚美辛的释放率小于1%。然而,进入模拟肠液(pH值为6.8)时,含药室囊壁中的HPMCP微球溶解,释药“微通道”(microchannel)被打开,同时助推室中的PAA发生溶胀,为药物的释放提供推动力。结果,吲哚美辛在小肠中以恒定的速度释放60%以上。因此,该θ-ACPSi 微胶囊具有良好的泵送和肠靶向控释性能,为口服肠道靶向给药系统的开发提供了一种新策略。

关键词: 微胶囊     海藻酸钙     肠靶向递送     泵送性能     控制释放    

封装分子识别纳米凝胶的功能胶囊用于简捷有效移除水中有机微污染物 Article

刘文英, 巨晓洁, 蒲兴群, 蔡泉威, 刘玉琼, 刘壮, 汪伟, 谢锐, 褚良银

《工程(英文)》 2021年 第7卷 第5期   页码 636-646 doi: 10.1016/j.eng.2021.02.007

摘要:

本文提出了一种利用封装具有分子识别特性纳米凝胶的功能胶囊简捷有效移除水中有机微污染物(OMP)的新方法。该功能胶囊由具有半透膜特性的海藻酸钙(Ca-Alg)凝胶囊膜和具有分子识别特性的聚[N-异丙基丙烯酰胺-共聚-丙烯酸-接枝-单(6-乙二胺基-6-去氧)-β-环糊精](PNCD)纳米凝胶组成。其中,具有半透膜特性的Ca-Alg凝胶囊膜可以使OMP和水分子自由跨膜传输进入囊的内部,而截留封装的PNCD纳米凝胶。以具有毒性且在水中分布较广的双酚A(BPA)作为模型OMP,基于主-客体识别络合作用,PNCD纳米凝胶上的CD基团能够有效捕捉BPA分子。基于此,将功能胶囊置于含有BPA的水溶液中,即可实现水中OMP的简捷有效移除。另外,由于功能胶囊具有毫米尺度,进一步利用滤网即可便捷地将胶囊从溶液中分离出来。该功能胶囊对BPA的吸附动力学符合拟二级动力学模型,且其等温吸附热力学同时满足Freundlich以及Langmuir等温吸附模型。另外,由于所制备的PNCD纳米凝胶具有温敏性,进一步利用纯水,在高于PNCD纳米凝胶的体积相变温度的条件下,反复清洗胶囊即可实现胶囊的循环再生利用。因此,本研究提出的方法
为简捷有效地移除水中OMP提供了一种新的策略。

关键词: 功能胶囊     分子识别纳米凝胶     有机微污染物     主–客体络合     分离    

标题 作者 时间 类型 操作

Encapsulation of polyethylene glycol in cellulose-based porous capsules for latent heat storage and light-to-thermal

期刊论文

Ingestible wireless capsules for enhanced diagnostic inspection of gastrointestinal tract

Mahdi RASOULI, Andy Prima KENCANA, Van An HUYNH, Eng Kiat TING, Joshua Chong Yue LAI, Kai Juan WONG, Su Lim TAN, Soo Jay PHEE

期刊论文

具有泵送控释性能的肠靶向Janus型双腔室海藻酸钙基微胶囊

温霜, 巨晓洁, 刘文英, 刘玉琼, 蒲兴群, 刘壮, 汪伟, 谢锐, Yousef Faraj, 褚良银

期刊论文

封装分子识别纳米凝胶的功能胶囊用于简捷有效移除水中有机微污染物

刘文英, 巨晓洁, 蒲兴群, 蔡泉威, 刘玉琼, 刘壮, 汪伟, 谢锐, 褚良银

期刊论文