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Ecological compensation mechanism for urban green land and its application in Shanghai, China

WANG Yan, DING Xiaowen, QIAN Longxia, WANG Hongrui

《环境科学与工程前沿（英文）》 2007年第1卷第3期页码 320-324 doi: 10.1007/s11783-007-0054-9

摘要： Urban green land compensation plays an important role in county development, ecological environment management and many other fields. The concept, methods and principles of urban green land are introduced in this paper. According to the pay fee method, the value and ecological function of various types of urban green land were analyzed. The cost-benefit analysis method (CBAM) was used to estimate different external diseconomy benefits caused by green land loss. The authors applied CBAM to estimate such benefits in the case of Shanghai, China, and calculated the actual compensation value for green land. Results indicated that in 2002, the compensation value for the green land of Shanghai was RMB 8.58 × 10 Yuan/hm.

关键词： development Yuan/hm different external concept cost-benefit analysis

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A small-molecule pan-HER inhibitor alone or in combination with cisplatin exerts efficacy against nasopharyngeal carcinoma

《医学前沿（英文）》 2023年第17卷第2期页码 275-289 doi: 10.1007/s11684-022-0945-y

摘要： The abnormal activation of HER family kinase activity is closely related to the development of human malignancies. In this study, we used HER kinases as targets for the treatment of nasopharyngeal carcinoma (NPC) and explored the anti-tumor effects of the novel pan-HER inhibitor HM781-36B, alone or in combination with cisplatin. We found that HER family proteins were positively expressed in tumor tissues of some NPC patients, and the high levels of those proteins were significantly related to poor prognosis. HM781-36B inhibited NPC in vitro and in vivo. HM781-36B exerted synergistic effects with cisplatin on inhibiting proliferation and promoting apoptosis of NPC cells. In NPC xenograft models in nude mice, HM781-36B and cisplatin synergistically inhibited tumor growth. Downregulating the activity of HER family proteins and their downstream signaling pathways and regulating tumor microenvironment may explain the synergistic anti-tumor effects of HM781-36B and cisplatin. In conclusion, our study provides evidence for HER family proteins as prognostic biomarkers and potential therapeutic targets for NPC. The pan-HER inhibitor HM781-36B alone or in combination with cisplatin represents promising therapeutic effects for the treatment of NPC patients, which provides a new idea for the comprehensive treatment of NPC.

关键词： epidermal growth factor receptor ErbB receptors HM781-36B nasopharyngeal carcinoma molecular targeted therapy cisplatin

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Synthesis and characterization of biocompatible polyurethanes for controlled release of hydrophobic and hydrophilic drugs

Juichen YANG,Hong CHEN,Yuan YUAN,Debanjan SARKAR,Jie ZHENG

《化学科学与工程前沿（英文）》 2014年第8卷第4期页码 498-510 doi: 10.1007/s11705-014-1451-9

摘要： Design of biocompatible and biodegradable polymer systems for sustained and controlled release of bioactive agents is critical for numerous biomedical applications. Here, we designed, synthesized, and characterized four polyurethane carrier systems for controlled release of model drugs. These polyurethanes are biocompatible and biodegradable because they consist of biocompatible poly(ethylene glycol) or poly(caprolactone diol) as soft segment, linear aliphatic hexamethylene diisocyanate or symmetrical aliphatic cyclic dicyclohexylmethane-4,4′-diisocyanate as hard segment, and biodegradable urethane linkage. They were characterized with Fourier transform infrared spectroscopy, atomic force microscope, and differential scanning calorimetry, whereas their degradation behaviors were investigated in both phosphate buffered saline and enzymatic solutions. By tuning polyurethane segments, different release profiles of hydrophobic and hydrophilic drugs were obtained in the absence and presence of enzymes. Such difference in release profiles was attributed to a complex interplay among structure, hydrophobicity, and degradability of polyurethanes, the size and hydrophobicity of drugs, and drug-polymer interactions. Different drug-polyurethane combinations modulated the distribution and location of the drugs in polymer matrix, thus inducing different drug release mechanisms. Our results highlight an important role of segmental structure of the polyurethane as an engineering tool to control drug release.

关键词： phase structure degradation polyurethanes controlled release drug delivery

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Relationship of adrenomedullin expression and microvessel density and prognosis in smooth muscle tumor of uterus

JIANG Yuan, TIAN Xuehong, YUAN Jie, JIN Yuemei, TAN Yusong

《医学前沿（英文）》 2007年第1卷第4期页码 398-400 doi: 10.1007/s11684-007-0077-4

摘要： The aim of this paper was to investigate the relationship between the expression of adrenomedullin (ADM) and microvessel density (MVD) and prognosis in smooth muscle tumor of uterus. The expression of ADM was detected using immunohistochemical staining in specimens from 15 normal controls, 28 cases of uterine leiomyoma (LE) and 19 cases of uterine leiomyosarcoma (LES). The MVD was assayed by immunostainting with CD. There was a positive correlation between the ADM expression and MVD in LE and LES respectively ( = 0.823, <0.01; = 0.793, <0.01). The expression of ADM in LE was statistically lower than that in LES (<0.05). There was a positive correlation between the ADM expression and mitotic figures in LES (<0.05): the more mitotic figures, the higher levels of the ADM expression and poor prognosis. The ADM is an important angiogenic factor in smooth muscle tumor of uterus. The ADM can be used as an accessory marker in estimating the malignant potency of LE and judging the pro gnosis of LES, and as a novel molecular target of anti-angiogenic and anticarcinogenic strategies.

关键词： anticarcinogenic microvessel density malignant potency muscle uterine leiomyosarcoma

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Analysis of radiation heat transfer and temperature distributions of solar thermochemical reactor for syngas production

Bachirou GUENE LOUGOU, Yong SHUAI, Xiang CHEN, Yuan YUAN, Heping TAN, Huang XING

《能源前沿（英文）》 2017年第11卷第4期页码 480-492 doi: 10.1007/s11708-017-0506-2

摘要： This paper investigated radiation heat transfer and temperature distributions of solar thermochemical reactor for syngas production using the finite volume discrete ordinate method (fvDOM) and P1 approximation for radiation heat transfer. Different parameters including absorptivity, emissivity, reflection based radiation scattering, and carrier gas flow inlet velocity that would greatly affect the reactor thermal performance were sufficiently investigated. The fvDOM approximation was used to obtain the radiation intensity distribution along the reactor. The drop in the temperature resulted from the radiation scattering was further investigated using the P1 approximation. The results indicated that the reactor temperature difference between the P1 approximation and the fvDOM radiation model was very close under different operating conditions. However, a big temperature difference which increased with an increase in the radiation emissivity due to the thermal non-equilibrium was observed in the radiation inlet region. It was found that the incident radiation flux distribution had a strong impact on the temperature distribution throughout the reactor. This paper revealed that the temperature drop caused by the boundary radiation heat loss should not be neglected for the thermal performance analysis of solar thermochemical reactor.

关键词： solar thermochemical reactor incident radiation flux temperature distribution radiation absorptivity radiation emissivity thermal performance analysis

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A thermoelectric generator and water-cooling assisted high conversion efficiency polycrystalline silicon photovoltaic system

Zekun LIU, Shuang YUAN, Yi YUAN, Guojian LI, Qiang WANG

《能源前沿（英文）》 2021年第15卷第2期页码 358-366 doi: 10.1007/s11708-020-0712-1

摘要： Solar energy has been increasing its share in the global energy structure. However, the thermal radiation brought by sunlight will attenuate the efficiency of solar cells. To reduce the temperature of the photovoltaic (PV) cell and improve the utilization efficiency of solar energy, a hybrid system composed of the PV cell, a thermoelectric generator (TEG), and a water-cooled plate (WCP) was manufactured. The WCP cannot only cool the PV cell, but also effectively generate additional electric energy with the TEG using the waste heat of the PV cell. The changes in the efficiency and power density of the hybrid system were obtained by real time monitoring. The thermal and electrical tests were performed at different irradiations and the same experiment temperature of 22°C. At a light intensity of 1000 W/m , the steady-state temperature of the PV cell decreases from 86.8°C to 54.1°C, and the overall efficiency increases from 15.6% to 21.1%. At a light intensity of 800 W/m , the steady-state temperature of the PV cell decreases from 70°C to 45.8°C, and the overall efficiency increases from 9.28% to 12.59%. At a light intensity of 400 W/m , the steady-state temperature of the PV cell decreases from 38.5°C to 31.5°C, and the overall efficiency is approximately 3.8%, basically remain unchanged.

关键词： photovoltaic (PV) thermoelectric generator conversion efficiency hybrid energy systems water-cooled plate (WCP)

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SCRaMbLE drive application of synthetic yeast genome

Jin Jin, Yuan Ma, Duo Liu

《化学科学与工程前沿（英文）》 2018年第12卷第4期页码 832-834 doi: 10.1007/s11705-018-1749-0

摘要：

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Retraction Note to: Simulate oil spill weathering with system dynamic model

Aihaiti Kasimu, Junran Dong, Yuan Bian, Desheng WU

《工程管理前沿（英文）》页码 695-695 doi: 10.1007/s42524-020-0120-6

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Highlights of special issue on “Sustainable Phosphorus Use in Agri-Food System”

Hans LAMBERS, Lixing YUAN, Xuejun LIU

《农业科学与工程前沿（英文）》 2020年第7卷第4期页码 530-530 doi: 10.15302/J-FASE-2019316

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The effects of festivals and special events on city image design

LIU Yuan, CHEN Chong

《结构与土木工程前沿（英文）》 2007年第1卷第2期页码 255-259 doi: 10.1007/s11709-007-0032-0

摘要： City marketing provides a good vehicle to strengthen a city in competition. On the analysis of the important roles of events and city image in the context of city marketing, this paper suggests that holding festivals or special events is an effective approach to enhance city marketing. The positive impacts of festivals and special events, such as the identification of city image, the promotion of the transmission of city image, and the reversal of the negative image of the city, are discussed. The negative impacts of festivals and special events are also talked about. The unique image of the city could be identified by the City Mind Identity, the City Visual Identity and the City Behavior Identity concerned with festivals and special events.

关键词： Visual Identity reversal transmission marketing Behavior Identity

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Force fluctuations in sheared granular disks

Mingbo YUAN, Qicheng SUN, Feng JIN

《结构与土木工程前沿（英文）》 2013年第7卷第1期页码 46-49 doi: 10.1007/s11709-013-0189-7

摘要： The internal structure established within granular materials, often observed as force chains, is dominant in controlling bulk mechanical properties. We designed a two-dimensional Hele-Shaw cell to contain photoelastic disks, and two servos were used on the top and right boundaries individually. We experimentally monitored the fluctuations in force on the top plate while slowing the shearing of the well-confined disks and keeping the right boundary at a contact-confined force of 0.2 kN. The particle rearrangements were found to correspond to bulk force drops and were observed in a localized zone with a length of approximately 5 particle diameters. These results help reveal the structure and mechanics of granular materials, and further investigations are ongoing.

关键词： granular matter force chain stick and slip

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Effect of inlet box on performance of axial flow fans

LI Jingyin, TIAN Hua, YUAN Xiaofang

《能源前沿（英文）》 2008年第2卷第4期页码 390-394 doi: 10.1007/s11708-008-0087-1

摘要： Numerical investigations on 3D flow fields in an axial flow fan with and without an inlet box have been extensively conducted, focusing on the variation of fan performance caused by the internal flow fields and the velocity evenness at the exit of the inlet box. It is interesting to find that although the inlet box is well designed in accordance with basic design principles, there is a flow separation region in it. Furthermore, this flow separation and the resulting uneven velocity distribution at the exit lead to some decrease in the efficiency and an increase in the total pressure rise of the fan. This research shows that the inlet box needs further improvement and such a check on the flow fields is of value for the design of inlet boxes.

关键词： box velocity distribution accordance Numerical variation

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Influences of additives on the crystal habit of potassium chloride

Xiaofu GUO, Junsheng YUAN, Zhiyong JI, Min SU,

《化学科学与工程前沿（英文）》 2010年第4卷第1期页码 78-81 doi: 10.1007/s11705-009-0300-8

摘要： By means of constant control speed cooling crystallization, the influences of four additives, including lead chloride, cadmium chloride, sodium salicylate, and quaternary ammonium salt, on the crystal habit of KCl were investigated. The results show that the crystal habit of KCl is cube without additives, the crystal habit of KCl is ellipsoid-like in the presence of Pb, the crystal habit of KCl is strip in the presence of Cd, and the crystal habit of KCl is cavate cube in the presence of sodium salicylate. X-ray diffractometry analysis reveals that these additives can change the crystal habit of KCl but not its crystal structure.

关键词： cadmium chloride salicylate presence crystallization diffractometry analysis

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Lamb wave propagation modeling for structure health monitoring

Xiaoyue ZHANG, Shenfang YUAN, Tong HAO

《机械工程前沿（英文）》 2009年第4卷第3期页码 326-331 doi: 10.1007/s11465-009-0045-6

摘要： This study aims to model the propagation of Lamb waves used in structure health monitoring. A number of different numerical computational techniques have been developed for wave propagation studies. The local interaction simulation approach, used for modeling sharp interfaces and discontinuities in complex media (LISA/SIM theory), has been effectively applied to numerical simulations of elastic wave interaction. This modeling is based on the local interaction simulation approach theory and is finally accomplished through the finite elements software Ansys11. In this paper, the Lamb waves propagating characteristics and the LISA/SIM theory are introduced. The finite difference equations describing wave propagation used in the LISA/SIM theory are obtained. Then, an anisotropic metallic plate model is modeled and a simulating Lamb waves signal is loaded on. Finally, the Lamb waves propagation modeling is implemented.

关键词： Lamb wave modeling LISA/SIM theory finite difference equation finite element

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Low crosstalk switch unit for dense piezoelectric sensor networks

Lei QIU, Shenfang YUAN,

《机械工程前沿（英文）》 2009年第4卷第4期页码 401-406 doi: 10.1007/s11465-009-0047-4

摘要： Structural health monitoring (SHM), on the basis of piezoelectric (PZT) sensors and lamb wave method, is efficient in estimating the state of monitored structures. Furthermore, to monitor large-scale structures, dense piezoelectric sensor networks are required, which usually contain many piezoelectric sensor pairs called actuator-sensor channels. In that case, considering the few data acquisition channels especially in the data acquisition board with a high sampling rate and limited quantity of signal amplifiers used in an integrated computer system, a switch unit is adopted to switch to different channels. Because of the high frequency and power of the lamb wave excitation signal, there exists a crosstalk signal in the switch unit. A large crosstalk signal is mixed into the response signal so that the on/off-line signal processing task is difficult to achieve. This paper first analyzes the crosstalk signal phenomenon, describes its production mechanism, and proposes a method to reduce it. Then a 24-switch channel low crosstalk switch unit based on a digital I/O board PCI7248 produced by Adlink technology is developed. An experiment is implemented to validate it. Its low crosstalk characteristics make it promote the real application of the SHM based active lamb wave method. Finally, a general software program based on LabVIEW software platform is developed to control this switch unit.

关键词： structural health monitoring (SHM) piezoelectric (PZT) sensor networks switch unit crosstalk signal