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固态发酵 1

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EMBRYOGENESIS ABUNDANT FAMILY GENE FROM PONCIRUS TRIFOLIATA, CONFERS ENHANCED DROUGHT TOLERANCE BY ENHANCING ANTIOXIDANT

《农业科学与工程前沿(英文)》 2021年 第8卷 第2期

摘要:

Late embryogenesis abundant (LEA) genes encode highly hydrophilic proteins that are essential in abiotic stress responses. However, most LEA genes in higher plants have not yet been investigated. This study identified an LEA family gene (PtrLEA7) from Poncirus trifoliata and studied its function in drought tolerance. The full-length coding sequence of PtrLEA7 was 420 bp encoding a protein of 139 amino acids. Phylogenetic analysis shows that PtrLEA7 protein belongs to the LEA_4 subfamily. Expression profiling by qPCR found that PtrLEA7 was strongly induced by dehydration, cold and ABA treatments, and slightly induced by salt stress. Subcellular localization reveals that PtrLEA7 protein was located in both cytoplasm and nucleus. To investigate its function, transgenic plants of both tobacco and Poncirus trifoliata overexpressing PtrLEA7 were obtained. Stress tolerance assays show that overexpression lines had enhanced dehydration and drought tolerance compared with wild type plants, indicating that PtrLEA7 positively regulates drought tolerance. In addition, transgenic plants had much higher expression levels of three antioxidant enzyme genes (CAT, SOD and POD) and significantly increased catalase enzyme activity, accompanied by reduced reactive oxygen species accumulation in comparison with wild type plants. Collectively, this study demonstrates that PtrLEA7 can confer enhanced drought tolerance partially via enhancing antioxidant capacity.

 

Polyamines and antioxidant defense system are associated with cold tolerance in centipedegrass

Jingjing CHEN, Junyang FANG, Zhenfei GUO, Shaoyun LU

《农业科学与工程前沿(英文)》 2018年 第5卷 第1期   页码 129-138 doi: 10.15302/J-FASE-2017197

摘要: Physiological responses to low temperature were analyzed in a chilling-tolerant centipedegrass ( ) accession, Shao Guan (SG), in comparison to the commercial cultivar, Common. Lower levels of ion leakage and higher chlorophyll (Chl) concentration were observed in SG than in Common during chilling stress. The maximum photochemical efficiency, the actual photosystem II (PSII) efficiency, photochemical quenching efficiency, and net photosynthetic rate were decreased during chilling stress in both genotypes, with higher levels of these parameters shown by SG than Common. In addition, higher activities of superoxide dismutase (SOD), catalase (CAT), ascorbate-peroxidase (APX) and glutathione reductase (GR), and higher concentrations of ascorbic acid (AsA) and glutathione (GSH) were observed in SG than in Common. Moreover, higher concentrations of putrescine (Put), spermidine (Spd), and spermine (Spm) were observed in SG than in Common. Correlation analysis indicated that SOD, CAT, APX and GR activities, and AsA and GSH concentrations showed high correlation to Put, while APX, GR, and AsA concentrations were correlated to Spd. Exogenous Put or Spd increased antioxidant enzyme activities and chilling tolerance. The results suggested that polyamine-regulated antioxidants are important for chilling tolerance in centipedegrass and protect plants against chilling induced oxidative damage.

关键词: antioxidants     centipedegrass     chilling     photosynthesis     polyamines    

OVEREXPRESSION OF

Tonglu WEI, Dalong GUO, Jihong LIU

《农业科学与工程前沿(英文)》   页码 236-246 doi: 10.15302/J-FASE-2020368

摘要: Late embryogenesis abundant (LEA) genes encode highly hydrophilic proteins that are essential in abiotic stress responses. However, most LEA genes in higher plants have not yet been investigated. This study identified an LEA family gene (PtrLEA7) from Poncirus trifoliata and studied its function in drought tolerance. The full-length coding sequence of PtrLEA7 was 420 bp encoding a protein of 139 amino acids. Phylogenetic analysis shows that PtrLEA7 protein belongs to the LEA_4 subfamily. Expression profiling by qPCR found that PtrLEA7 was strongly induced by dehydration, cold and ABA treatments, and slightly induced by salt stress. Subcellular localization reveals that PtrLEA7 protein was located in both cytoplasm and nucleus. To investigate its function, transgenic plants of both tobacco and Poncirus trifoliata overexpressing PtrLEA7 were obtained. Stress tolerance assays show that overexpression lines had enhanced dehydration and drought tolerance compared with wild type plants, indicating that PtrLEA7 positively regulates drought tolerance. In addition, transgenic plants had much higher expression levels of three antioxidant enzyme genes (CAT, SOD and POD) and significantly increased catalase enzyme activity, accompanied by reduced reactive oxygen species accumulation in comparison with wild type plants. Collectively, this study demonstrates that PtrLEA7 can confer enhanced drought tolerance partially via enhancing antioxidant capacity.

关键词: abiotic stress     antioxidant     drought     late embryogenesis abundant     Poncirus trifoliata    

Antioxidant and antitumor effects and immunomodulatory activities of crude and purified polyphenol extract

Xiaohong Kou,Lihua Han,Xingyuan Li,Zhaohui Xue,Fengjuan Zhou

《化学科学与工程前沿(英文)》 2016年 第10卷 第1期   页码 108-119 doi: 10.1007/s11705-016-1553-7

摘要: The antioxidant and antitumor effects as well as the immunomodulatory activities of crude and purified polyphenol extract from blueberries were investigated. The antioxidant and antitumor effects of the polyphenol extract were measured both and , and their effect on the immune systems of CD-1 tumor-bearing mice were also analyzed. assays demonstrated that blueberry purified polyphenol extract (BBPP) exhibited higher antioxidant activities than blueberry crude polyphenol extract (BBCP), but the opposite effect was observed . Both the and antitumor activity and the immunity assay showed that BBCP not only inhibited tumor growth, but also significantly improved the immunity of the mice. According to physical and histological studies, the CD-1 tumor-bearing mice treated with the polyphenol extract, especially high doses of BBCP experienced a higher quality of life than the positive control group (treated with cyclophosphamide). These results indicate that BBCP has significant antioxidant and antitumor activities and that it can enhance the immunity of CD-1 tumor-bearing mice.

关键词: crude polyphenol extract     purified polyphenol extract     blueberry     antioxidant     antitumor     immunity    

Inhibition of NO emission by adding antioxidant mixture in

A. PRABU,R. B. ANAND

《能源前沿(英文)》 2015年 第9卷 第2期   页码 238-245 doi: 10.1007/s11708-015-0356-8

摘要: In this paper, the effect of adding an antioxidant mixture in biodiesel as fuel, in a single cylinder, direct injection compression ignition engine was experimentally investigated and the level of pollutants in the exhaust and performance characteristics of the engine were analyzed. Nine test fuels were prepared with three antioxidants, namely, Succinimide (C H NO ), , dimethyl- -phenylenediamine-dihydrochloride (C H Cl N ), and -phenyl- -phenylenediamine (C H NHC H NH ) added to neat biodiesel at 500 parts per million (ppm), 1000 ppm and 2000 ppm and the observed experimental results were compared with those of neat biodiesel and neat diesel as base fuels. The comparison showed that NO emission was reduced drastically for the test fuels with the antioxidant addition of 2000 ppm. The maximum reduction of 10% of NO emission was observed for the antioxidant mixture in neat biodiesel, with a slight increase in unburned HC, CO and smoke opacity. In addition, the obtained experimental results reveal that the addition of two antioxidants as mixture in neat biodiesel caused improved NO emission reduction for all test fuels.

关键词: NO emission     antioxidants     Succinimide     N     N-dimethyl-p-phenylenediamine-dihydrochloride     N-phenyl-p-phenylenediamine    

Zinc homeostasis in the metabolic syndrome and diabetes

null

《医学前沿(英文)》 2013年 第7卷 第1期   页码 31-52 doi: 10.1007/s11684-013-0251-9

摘要:

Zinc (Zn) is an essential mineral that is required for various cellular functions. Zn dyshomeostasis always is related to certain disorders such as metabolic syndrome, diabetes and diabetic complications. The associations of Zn with metabolic syndrome, diabetes and diabetic complications, thus, stem from the multiple roles of Zn: (1) a constructive component of many important enzymes or proteins, (2) a requirement for insulin storage and secretion, (3) a direct or indirect antioxidant action, and (4) an insulin-like action. However, whether there is a clear cause-and-effect relationship of Zn with metabolic syndrome, diabetes, or diabetic complications remains unclear. In fact, it is known that Zn deficiency is a common phenomenon in diabetic patients. Chronic low intake of Zn was associated with the increased risk of diabetes and diabetes also impairs Zn metabolism. Theoretically Zn supplementation should prevent the metabolic syndrome, diabetes, and diabetic complications; however, limited available data are not always supportive of the above notion. Therefore, this review has tried to summarize these pieces of available information, possible mechanisms by which Zn prevents the metabolic syndrome, diabetes, and diabetic complications. In the final part, what are the current issues for Zn supplementation were also discussed.

关键词: zinc     zinc transporters     metallothionein     diabetes     diabetic complications     insulin resistance     antioxidant    

Effects of

Yuping ZHANG, Yanfei ZHOU, Xingxu ZHANG, Tingyu DUAN, Zhibiao NAN

《农业科学与工程前沿(英文)》 2018年 第5卷 第1期   页码 148-158 doi: 10.15302/J-FASE-2017195

摘要: Fungal endophytes of some cultivated grasses can increase plant performance and competitive abilities, especially under stress. Far less is known about the influence of infections in wild populations of wild grasses. In this study, plants of three ecotypes (WLS, QY and WTS) either infected with endophyte (E+) or uninfected (E–) were grown in the field. The activities of the antioxidant enzymes ascorbate peroxidase, catalase, peroxidase and superoxide dismutase, and concentrations of H O and malondialdehyde were examined in the leaves of E+ and E– plants. We also determined photosynthesis parameters, leaf blade and sheath carbohydrate concentration and plant growth parameters of both E+ and E– plants. E+ plants from the WLS and QY populations had significantly higher antioxidant enzyme activities and photosynthetic capability ( <0.05), superior growth characteristics including more abundant carbohydrate concentration than E– plants. In contrast, in plants from the WTS population, the endophyte had no significant effect on reactive oxygen species scavenging capability and growth performance ( >0.05), and even displayed some negative effects on plant photosynthetic capability. Thus, endophyte infection significantly affected antioxidant enzyme activities ( <0.05), photosynthesis and growth capability, although, the effects varied with plant ecotypes.

关键词: antioxidant enzymes     Elymus dahuricus     Epichloë     fungal endophyte     photosynthesis    

Joint effects of Penta-BDE and heavy metals on

Baohua TANG, Lingyan ZHU, Qixing ZHOU

《环境科学与工程前沿(英文)》 2011年 第5卷 第1期   页码 99-110 doi: 10.1007/s11783-010-0260-8

摘要: The joint toxicity of Penta-BDE (Pe-BDE) and heavy metals including cadmium and copper on ( ) was evaluated on the basis of determining the 48 h survival, antioxidative enzyme responses, and lipid peroxidation. The response was classified as additive, greater than additive, or less than additive by comparing the measured “toxic units, TU” with one. Based on the survival of , less-than-additive interactions were found in most of mixtures treatments. This may be attributed to the different toxicity mechanism between Pe-BDE and metals. Cu and Cd played a greater role in toxicity than what Pe-BDE did. As for the superoxide dismutase (SOD) and catalase (CAT) activity, most response was less than additive. For the glutathione -transferases (GST) activity, most of the greater-than-additive responses were found in the Cu plus Pe-BDE treatments, but the additive responses occurred in Cd plus Pe-BDE treatments and binary metal treatments. For lipid peroxide levels, which were measured as malondialdehyde (MDA) levels, less-than-additive response occurred in the 50% Cd plus 50% Cu and ternary mixture treatments. Results suggested that Pe-BDE, Cd, and Cu could induce different patterns of antioxidant enzyme responses, such as antioxidant/prooxidant responses, depending on their capability to produce reactive oxygen species and antioxidant enzymes to detoxify them.

关键词: polybrominated diphenyl ethers (PBDEs)     heavy metal     mixture toxicity     toxic units (TUs)     antioxidant enzyme     lipid peroxidation    

EXTRACTION AND EVALUATION OF EDIBLE OIL FROM SCHIZOCHYTRIUM SP. USING AN AQUEOUS ENZYMATIC METHOD

《农业科学与工程前沿(英文)》 2021年 第8卷 第4期   页码 623-634 doi: 10.15302/J-FASE -2021400

摘要:

Schizochytrium sp., a marine microalga, is a potential source of edible oil due to its short growth cycle and rapid lipid accumulation, especially of docosahexaenoic acid. An approach to isolate edible microalgal oil from Schizochytrium sp. using aqueous enzymatic extraction (AEE) was developed. Parameters were optimized by single-factor experiments followed by Box-Behnken design. Proteases were effective in extracting oil. The maximum free oil recovery (49.7%±0.58%) and total oil recovery (68.1%±0.94%) were obtained under optimum conditions of liquid-to-solid ratio of 4.8:1, a 2.5% enzyme concentration of papain and an extraction time of 2.2 h. There was a significant difference (P<0.05) in polyunsaturated fatty acid composition between microalgal oil obtained by AEE and by Soxhlet extraction, with the former having superior physiochemical properties and higher concentrations of bioactive components including total phenolic compounds and total tocopherols. These findings indicate a potential application of AEE for extraction of oil from Schizochytrium sp.

 

关键词: antioxidant activity / aqueous enzymatic extraction / edible microalgal oil / fatty acid composition / physicochemical properties    

Single and joint effects of HHCB and cadmium on zebrafish (

Lei ZHANG, Jing AN, Qixing ZHOU

《环境科学与工程前沿(英文)》 2012年 第6卷 第3期   页码 360-372 doi: 10.1007/s11783-011-0353-z

摘要: As an important type of emerging pollutants, ecological toxicity and risk of artificial musks are increasingly concerned. Thus, single and joint toxic effects of 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8- hexamethylcyclopenta-gamma-2-benzopyran (HHCB) as one of the most widely applied artificial musks and cadmium (Cd) as an toxic metal on zebrafish ( ) were investigated by the exposure of zebrafish to various concentrations of HHCB or/and Cd in feculent water containing bedloads. The results indicated that the joint effect of HHCB and Cd changed during different exposure times within 120 h. The index of the antioxidant enzyme system including superoxide dismutase (SOD) and peroxidase (POD), and malondialdehyde (MDA) were sensitive and induced in the zebrafish stressed by Cd, and content of soluble protein (SP) was sensitive to HHCB and could be used as a biomarker for HHCB. Joint effects on antioxidant enzymes depended more on the effect of single Cd in the first one or two days. However, in the rest exposure days, the effect of HHCB began to dominate in the joint effect during the exposure process.

关键词: 1     3     4     6     7     8-hexahydro-4     6     6     7     8     8-hexamethylcyclopenta-gamma-2-benzopyran (HHCB)     cadmium (Cd)     antioxidant biomarker     feculent water containing bedloads    

Antibacterial properties of extracts of

Manhong YE,Lei ZHANG,Jiaqi GE,Haifeng SUN,Jingjing NI,Shengmei YANG,Wanhong WEI

《农业科学与工程前沿(英文)》 2015年 第2卷 第4期   页码 327-334 doi: 10.15302/J-FASE-2015078

摘要: Canadian goldenrod ( ) is one of the most destructive invasive weeds in South-eastern China. To evaluate its potential application as dietary supplement in red swamp crayfish ( ), the antibacterial properties of aqueous and ethanol extracts of this plant against three major pathogenic bacteria in crayfish aquaculture were examined. Inhibition zone tests and determination of minimum inhibitory concentration revealed that the extracts had lower antibacterial activity than extracts from two traditional medicinal plants that possess antibacterial properties, garlic ( ) and cortex phellodendri ( ). However, they did exhibit greater antibacterial effects than extracts from another widely used medicinal plant, , and an aquatic weed, . Aqueous extracts of Canadian goldenrod gave greater inhibition than the ethanol extracts. Crayfish fed a diet with 2% these aqueous extracts exhibited significantly higher enzyme activity of alkaline phosphatase, catalase and phenoloxidase ( <0.05). Based on the results of this study, we conclude that aqueous extracts of Canadian goldenrod are highly promising for the development of new dietary supplement for use in crayfish aquaculture.

关键词: antibacterial activity     Canadian goldenrod     antioxidant enzyme     crayfish    

Oxidative stress and diabetes: antioxidative strategies

Pengju Zhang, Tao Li, Xingyun Wu, Edouard C. Nice, Canhua Huang, Yuanyuan Zhang

《医学前沿(英文)》 2020年 第14卷 第5期   页码 583-600 doi: 10.1007/s11684-019-0729-1

摘要: Diabetes mellitus is one of the major public health problems worldwide. Considerable recent evidence suggests that the cellular reduction–oxidation (redox) imbalance leads to oxidative stress and subsequent occurrence and development of diabetes and related complications by regulating certain signaling pathways involved in β-cell dysfunction and insulin resistance. Reactive oxide species (ROS) can also directly oxidize certain proteins (defined as redox modification) involved in the diabetes process. There are a number of potential problems in the clinical application of antioxidant therapies including poor solubility, storage instability and non-selectivity of antioxidants. Novel antioxidant delivery systems may overcome pharmacokinetic and stability problem and improve the selectivity of scavenging ROS. We have therefore focused on the role of oxidative stress and antioxidative therapies in the pathogenesis of diabetes mellitus. Precise therapeutic interventions against ROS and downstream targets are now possible and provide important new insights into the treatment of diabetes.

关键词: diabetes     oxidative stress     redox modification     antioxidative therapy     novel antioxidant delivery    

Performance and synergistic effect of phenolic and thio antioxidants in ABS graft copolymers

Gongsheng LI, Xuhong GUO, Wang NA, Diancheng HAO, Mingyao ZHANG, Huixuan ZHANG, Jun XU

《化学科学与工程前沿(英文)》 2011年 第5卷 第1期   页码 26-34 doi: 10.1007/s11705-010-0531-8

摘要: The synergistic effect of phenolic and thio antioxidants on the stabilization of acrylonitrile-butadiene-styrene (ABS) graft copolymers has been studied. Three commercial antioxidants Irganox245, Irganox1076 and dilauryl thiodipropionate (DLTP) were selected. Formulations based on hindered phenols and secondary antioxidant DLTP were prepared. Stabilization was monitored in terms of changes in the functional groups (oxidation products), tensile properties and yellowness index. Differential scanning calorimetry (DSC) and thermogravimetry (TG) were also used to assess the stability. The results indicated that the combination of Irganox245 and DLTP showed much better stabilization effect than the individual components due to the strong synergistic effect. Only weak synergism could be observed in the formulation that contained Irganox1076 and DLTP. Irganox1076 and Irgnox1076/DLTP exhibited similar behaviors between antioxidants with the highest and lowest efficiencies.

关键词: antioxidant     ABS graft copolymers     synergistic effect    

Protective effects of lignin fractions obtained from grape seeds against bisphenol AF neurotoxicity via antioxidative effects mediated by the Nrf2 pathway

《化学科学与工程前沿(英文)》 2023年 第17卷 第7期   页码 976-989 doi: 10.1007/s11705-022-2237-0

摘要: Lignin exhibits antioxidative and various other biological properties. However, its neuroprotection capability has rarely been studied. In this study, three types of lignin with different structures were prepared from grape seeds by using different isolation techniques. The antioxidative and neuroprotective effects of the lignin fractions were evaluated with the apoptosis model of murine neuroectodermal (NE-4C) neural stem cells stimulated with bisphenol AF. The results demonstrated that the half maximal inhibitory concentration for scavenging 2,2-diphenyl-1-picrylhydrazyl with water-soluble lignin (L-W, 58.19 μg·mL–1) was lower than those of lignin in the autohydrolyzed residue of grape seeds (84.27 μg·mL–1) and original lignin in grape seeds (99.44 μg·mL–1). BPAF exposure had negative effects on the reactive oxygen species, malondialdehyde content, and superoxide dismutase and glutathione peroxidase activities in NE-4C cells, which can be reversed by using the prepared lignin to reduce oxidative stress. An immunofluorescence assay demonstrated that grape seed lignin induced protective effects on BPAF-injured NE-4C cells via the nuclear factor erythroid 2-related Factor 2 pathway. In addition, correlational analyses showed that lignin (L-W) with lower molecular weights and noncondensed phenolic hydroxyl group content and higher contents of COOH groups effectively prevented cell apoptosis, scavenged reactive oxygen species, and ensured protection from nerve injury. This study demonstrated that grape seed lignin can be used as a neuroprotective agent and serves as a demonstration of active lignin production from grape seed waste.

关键词: grape seed lignin     structure     antioxidant     NE-4C cells     neuroprotection    

解淀粉芽孢杆菌发酵红小豆的理化特性和生物活性 Article

吴珊, 卢帅, 刘军, 杨绍青, 闫巧娟, 江正强

《工程(英文)》 2021年 第7卷 第2期   页码 219-225 doi: 10.1016/j.eng.2020.10.010

摘要:

本研究采用解淀粉芽孢杆菌发酵红小豆(Vigna umbellata),并评价了发酵红小豆的理化特性和生物活性。以纤溶酶活性为指标优化了发酵条件,在最适发酵条件下,纤溶酶活性最高达78.0 FU∙g-1(4890 IU∙g-1,纤维蛋白平板法)。发酵红小豆中多肽含量(2.1~10.9 g∙100 g-1)、总酚含量(116.7~388.5 mg没食子酸∙100 g-1)、总黄酮含量(235.5~354.3 mg芦丁∙100 g-1)、花青素含量(20.1~47.1 mg∙100 g-1)和超氧化物歧化酶活性(55.3~263.6 U∙g-1)显著增加。红小豆经发酵后的2,2-二苯基-1-苦肼基(DPPH)和2,2-联氮双(3-乙基苯并噻唑啉-6-磺酸)二铵盐(ABTS)自由基清除活性和铁离子还原抗氧化能力(FRAP)较未发酵的红小豆提高1.9~4.8倍。此外,发酵红小豆的二肽基肽酶Ⅳ(DPP-Ⅳ)抑制活性、α-葡萄糖苷酶抑制活性和抗凝血活性显著提高。解淀粉芽孢杆菌发酵红小豆具有多种功能活性,对开发预防血栓性疾病的功能食品具有重要意义。

关键词: 固态发酵     红小豆     解淀粉芽孢杆菌     抗血栓活性     抗氧化活性     降血糖活性    

标题 作者 时间 类型 操作

EMBRYOGENESIS ABUNDANT FAMILY GENE FROM PONCIRUS TRIFOLIATA, CONFERS ENHANCED DROUGHT TOLERANCE BY ENHANCING ANTIOXIDANT

期刊论文

Polyamines and antioxidant defense system are associated with cold tolerance in centipedegrass

Jingjing CHEN, Junyang FANG, Zhenfei GUO, Shaoyun LU

期刊论文

OVEREXPRESSION OF

Tonglu WEI, Dalong GUO, Jihong LIU

期刊论文

Antioxidant and antitumor effects and immunomodulatory activities of crude and purified polyphenol extract

Xiaohong Kou,Lihua Han,Xingyuan Li,Zhaohui Xue,Fengjuan Zhou

期刊论文

Inhibition of NO emission by adding antioxidant mixture in

A. PRABU,R. B. ANAND

期刊论文

Zinc homeostasis in the metabolic syndrome and diabetes

null

期刊论文

Effects of

Yuping ZHANG, Yanfei ZHOU, Xingxu ZHANG, Tingyu DUAN, Zhibiao NAN

期刊论文

Joint effects of Penta-BDE and heavy metals on

Baohua TANG, Lingyan ZHU, Qixing ZHOU

期刊论文

EXTRACTION AND EVALUATION OF EDIBLE OIL FROM SCHIZOCHYTRIUM SP. USING AN AQUEOUS ENZYMATIC METHOD

期刊论文

Single and joint effects of HHCB and cadmium on zebrafish (

Lei ZHANG, Jing AN, Qixing ZHOU

期刊论文

Antibacterial properties of extracts of

Manhong YE,Lei ZHANG,Jiaqi GE,Haifeng SUN,Jingjing NI,Shengmei YANG,Wanhong WEI

期刊论文

Oxidative stress and diabetes: antioxidative strategies

Pengju Zhang, Tao Li, Xingyun Wu, Edouard C. Nice, Canhua Huang, Yuanyuan Zhang

期刊论文

Performance and synergistic effect of phenolic and thio antioxidants in ABS graft copolymers

Gongsheng LI, Xuhong GUO, Wang NA, Diancheng HAO, Mingyao ZHANG, Huixuan ZHANG, Jun XU

期刊论文

Protective effects of lignin fractions obtained from grape seeds against bisphenol AF neurotoxicity via antioxidative effects mediated by the Nrf2 pathway

期刊论文

解淀粉芽孢杆菌发酵红小豆的理化特性和生物活性

吴珊, 卢帅, 刘军, 杨绍青, 闫巧娟, 江正强

期刊论文