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Genome-wide association study of the backfat thickness trait in two pig populations

Dandan ZHU,Xiaolei LIU,Rothschild MAX,Zhiwu ZHANG,Shuhong ZHAO,Bin FAN

《农业科学与工程前沿（英文）》 2014年 第1卷 第2期   页码 91-95 doi: 10.15302/J-FASE-2014005

摘要： Backfat thickness is a good predictor of carcass lean content, an economically important trait, and a main breeding target in pig improvement. In this study, the candidate genes and genomic regions associated with the tenth rib backfat thickness trait were identified in two independent pig populations, using a genome-wide association study of porcine 60K SNP genotype data applying the compressed mixed linear model (CMLM) statistical method. For each population, 30 most significant single-nucleotide polymorphisms (SNPs) were selected and SNP annotation implemented using Build 10.2. In the first population, 25 significant SNPs were distributed on seven chromosomes, and SNPs on SSC1 and SSC7 showed great significance for fat deposition. The most significant SNP (ALGA0006623) was located on SSC1, upstream of the gene. In the second population, 27 significant SNPs were recognized by annotation, and 12 SNPs on SSC12 were related to fat deposition. Two haplotype blocks, M1GA0016251-MARC0075799 and ALGA0065251-MARC0014203-M1GA0016298-ALGA0065308, were detected in significant regions where the and genes were identified as contributing to fat metabolism. The results indicated that genetic mechanism regulating backfat thickness is complex, and that genome-wide associations can be affected by populations with different genetic backgrounds.

关键词： backfat thickness     SNP chip     genome-wide association study     compressed mixed linear model     pig    

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A rain-on-snow mixed flood forecast model and its application

Jian WU, Lan LI,

《结构与土木工程前沿（英文）》 2009年 第3卷 第4期   页码 440-444 doi: 10.1007/s11709-009-0051-0

摘要： Based on summarizing the rule of rainstorm and snowmelt mixed flood, the structure of rain-on-snow runoff-generation is discussed; and critical temperature is used to determine the form of precipitation and snowmelt factor, taking into account rainfall volume of snowmelt. A rain-on-snow flood forecast model is developed by combining LL-Ⅰdistributed hydrology model. The Kalangguer River, an internal river in Xinjiang Autonomous Region, is taken for example. It is indicated that the model has a higher precision of forecasting; its determinacy coefficient is greater than 0.80.

关键词： Xinjiang Autonomous     forecasting     hydrology     temperature     rain-on-snow runoff-generation    

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General expression for linear and nonlinear time series models

Ren HUANG, Feiyun XU, Ruwen CHEN

《机械工程前沿（英文）》 2009年 第4卷 第1期   页码 15-24 doi: 10.1007/s11465-009-0015-z

摘要： The typical time series models such as ARMA, AR, and MA are founded on the normality and stationarity of a system and expressed by a linear difference equation; therefore, they are strictly limited to the linear system. However, some nonlinear factors are within the practical system; thus, it is difficult to fit the model for real systems with the above models. This paper proposes a general expression for linear and nonlinear auto-regressive time series models (GNAR). With the gradient optimization method and modified AIC information criteria integrated with the prediction error, the parameter estimation and order determination are achieved. The model simulation and experiments show that the GNAR model can accurately approximate to the dynamic characteristics of the most nonlinear models applied in academics and engineering. The modeling and prediction accuracy of the GNAR model is superior to the classical time series models. The proposed GNAR model is flexible and effective.

关键词： linear and nonlinear     autoregressive model     system identification     time series analysis    

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基于网络图拓扑结构的MILP模型求解智能制造系统中的工艺规划问题 Article

刘齐浩, 李新宇, 高亮

《工程（英文）》 2021年 第7卷 第6期   页码 807-817 doi: 10.1016/j.eng.2021.04.011

摘要： 从工艺网络图的拓扑结构出发，本文提出了一个全新的混合整数线性规划（mixedinteger linear programming, MILP）数学模型，并通过三种优先关系矩阵讨论了网络图中工序的优先关系

关键词： 智能工艺规划     工艺网路图     混合整数线性规划     CPLEX    

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Comparison between linear and non-linear forms of pseudo-first-order and pseudo-second-order adsorption

Junxiong LIN , Lan WANG ,

《环境科学与工程前沿（英文）》 2009年 第3卷 第3期   页码 320-324 doi: 10.1007/s11783-009-0030-7

摘要： The best-fit equations of linear and non-linear forms of the two widely used kinetic models, namely pseudo-first-order and pseudo-second-order equations, were compared in this study. The experimental kinetics of methylene blue adsorption on activated carbon was used for this research. Both the correlation coefficient () and the normalized standard deviation Δ(%) were employed as error analysis methods to determine the best-fitting equations. The results show that the non-linear forms of pseudo-first-order and pseudo-second-order models were more suitable than the linear forms for fitting the experimental data. The experimental kinetics may have been distorted by linearization of the linear kinetic equations, and thus, the non-linear forms of kinetic equations should be primarily used to obtain the adsorption parameters. In addition, the Δ(%) method for error analysis may be better to determine the best-fitting model in this case.

关键词： adsorption     pseudo-first order     pseudo-second order     kinetic model     linear method     non-linear method    

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An assemble-to-order production planning with the integration of order scheduling and mixed-model sequencing

Baoxi WANG, Zailin GUAN, Yarong CHEN, Xinyu SHAO, Ming JIN, Chaoyong ZHANG

《机械工程前沿（英文）》 2013年 第8卷 第2期   页码 137-145 doi: 10.1007/s11465-013-0251-0

摘要：

For assemble-to-order enterprises, both order scheduling and mixed-model sequencing need to be taken into consideration in the formulation of order-oriented assembly plan. First, determining production priority for the received orders, and then conducting assembly sequence to the mixed-model products in each order. Order scheduling is aimed to ensure order delivery with the optimization goal of minimal total overdue time, while product sequencing is aimed to minimize the makespan so as to meet the requirement on completion time of the order. In the end, the paper establishes a mixed integer programming model based on an industrial case, and makes programming calculation with Xpress-MP to accomplish an order-oriented assembly plan conforming to actual production.

关键词： mixed-model assembly line     assemble-to-order     order scheduling     sequencing    

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Cutting CO emissions through demand side regulation: Implications from multi-regional input–output linearprogramming model

《工程管理前沿（英文）》   页码 452-461 doi: 10.1007/s42524-022-0209-1

摘要： This study combines multi-regional input–output (MRIO) model with linear programming (LP) model to explore economic structure adjustment strategies for the reduction of carbon dioxide (CO2) emissions. A particular feature of this study is the identification of the optimal regulation sequence of final products in various regions to reduce CO2 emissions with the minimum loss in gross domestic product (GDP). By using China’s MRIO tables 2017 with 28 regions and 42 economic sectors, results show that reduction in final demand leads to simultaneous reductions in GDP and CO2 emissions. Nevertheless, certain demand side regulation strategy can be adopted to lower CO2 emissions at the smallest loss of economic growth. Several key final products, such as metallurgy, nonmetal, metal, and chemical products, should first be regulated to reduce CO2 emissions at the minimum loss in GDP. Most of these key products concentrate in the coastal developed regions in China. The proposed MRIO–LP model considers the inter-relationship among various sectors and regions, and can aid policy makers in designing effective policy for industrial structure adjustment at the regional level to achieve the national environmental and economic targets.

关键词： CO2 emissions     demand side regulation     multi-regional input–output model     linear programming model    

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使用数据驱动模型优化抗体纯化策略 Article

刘松崧, Lazaros G. Papageorgiou

《工程（英文）》 2019年 第5卷 第6期   页码 1077-1092 doi: 10.1016/j.eng.2019.10.011

摘要：

本工作致力于抗体片段纯化过程的多尺度优化。优化了生产过程中的色谱决策，包括色谱柱的数量及其大小，每批的循环数以及操作流速。使用基于微型实验数据的制造规模模拟数据集，建立了以负载质量、流速和柱床高度为输入的色谱通量数据驱动模型。与其他方法相比，分段线性回归建模方法具有简单、预测精度高的优点。提出了两种混合整数非线性规划（MINLP）模型，结合数据驱动模型，以最小化每克抗体纯化过程的总成本。然后，使用线性化技术和多参数分解将这些MINLP模型重新构造为混合整数线性规划（MILP）模型。研究了两个具有不同色谱柱尺寸替代品的工业相关案例，以证明所提出模型的适用性。

关键词： 抗体纯化     多尺度优化     抗原结合片段     混合整数规划     数据驱动模型     分段线性回归    

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A new approach for scheduling of multipurpose batch processes with unlimited intermediate storage policy

Nikolaos Rakovitis, Nan Zhang, Jie Li, Liping Zhang

《化学科学与工程前沿（英文）》 2019年 第13卷 第4期   页码 784-802 doi: 10.1007/s11705-019-1858-4

摘要： The increasing demand of goods, the high competitiveness in the global marketplace as well as the need to minimize the ecological footprint lead multipurpose batch process industries to seek ways to maximize their productivity with a simultaneous reduction of raw materials and utility consumption and efficient use of processing units. Optimal scheduling of their processes can lead facilities towards this direction. Although a great number of mathematical models have been developed for such scheduling, they may still lead to large model sizes and computational time. In this work, we develop two novel mathematical models using the unit-specific event-based modelling approach in which consumption and production tasks related to the same states are allowed to take place at the same event points. The computational results demonstrate that both proposed mathematical models reduce the number of event points required. The proposed unit-specific event-based model is the most efficient since it both requires a smaller number of event points and significantly less computational time in most cases especially for those examples which are computationally expensive from existing models.

关键词： scheduling     multipurpose batch processes     simultaneous transfer     mixed-integer linear programming    

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Model reduction techniques for dynamics analysis of ultra-precision linear stage

Xuedong CHEN, Zhixin LI

《机械工程前沿（英文）》 2009年 第4卷 第1期   页码 64-70 doi: 10.1007/s11465-009-0009-x

摘要： Spring-damping elements are used to simplify the internal interaction in the proposed finite element (FE) model of an ultra-precision linear stage. The dynamics behavior is studied. The comparison between mode shapes from the eigenvalue analysis shows that the components, except the translator, can represent system dynamics characteristics. A reduction approach is used to simplify the system in a dynamic studied. There is little difference between the vibration mode and the response analysis. The experimental modal analysis proves the validity of the reduction approach, which can be generalized to the development and dynamics characteristic study of a complex system model to obviously save computational resource.

关键词： dynamics analysis     air-bearing     linear stage     reduction    

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Multi-objective optimization for the multi-mode finance-based project scheduling problem

Sameh Al-SHIHABI, Mohammad AlDURGAM

《工程管理前沿（英文）》 2020年 第7卷 第2期   页码 223-237 doi: 10.1007/s42524-020-0097-1

摘要： The finance-based scheduling problem (FBSP) is about scheduling project activities without exceeding a credit line financing limit. The FBSP is extended to consider different execution modes that result in the multi-mode FBSP (MMFBSP). Unfortunately, researchers have abandoned the development of exact models to solve the FBSP and its extensions. Instead, researchers have heavily relied on the use of heuristics and meta-heuristics, which do not guarantee solution optimality. No exact models are available for contractors who look for optimal solutions to the multi-objective MMFBSP. CPLEX, which is an exact solver, has witnessed a significant decrease in its computation time. Moreover, its current version, CPLEX 12.9, solves multi-objective optimization problems. This study presents a mixed-integer linear programming model for the multi-objective MMFBSP. Using CPLEX 12.9, we discuss several techniques that researchers can use to optimize a multi-objective MMFBSP. We test our model by solving several problems from the literature. We also show how to solve multi-objective optimization problems by using CPLEX 12.9 and how computation time increases as problem size increases. The small increase in computation time compared with possible cost savings make exact models a must for practitioners. Moreover, the linear programming-relaxation of the model, which takes seconds, can provide an excellent lower bound.

关键词： multi-objective optimization     finance-based scheduling     multi-mode project scheduling     mixed-integer linear programming     CPLEX    

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Permeability and thermal conductivity of host compressed natural graphite for consolidated activated

Bo TIAN, Liwei WANG, Zhequan JIN, Ruzhu WANG

《能源前沿（英文）》 2011年 第5卷 第2期   页码 159-165 doi: 10.1007/s11708-011-0145-y

摘要： Permeability and thermal conductivity test units were set up to study the heat and mass transfer performance of the host material, i.e. expanded natural graphite (ENG), for consolidated activated carbon (AC) adsorbent. The permeability was tested with nitrogen as the gas source, and the thermal conductivity was studied using steady-state heat source method. The results showed that the values of permeability and thermal conductivity were 10 to 10 m and 1.7 to 3.2 W/(m·K), respectively, while the density compressed expanded natural graphite (CENG) varied from 100 to 500 kg/m . The permeability decreased with the increasing density of CENG, whereas the thermal conductivity increased with the increasing density of CENG. Then the thermal conductivity and permeability of granular AC were researched. It was discovered that the thermal conductivity of samples with different grain size almost kept constant at 0.36 W/(m·K) while the density was approximately 600 kg/m . This means that the thermal conductivity was not related to the grain size of AC. The thermal conductivity of CENG was improved by 5 to 10 times compared with that of granular AC. Such a result showed that CENG was a promising host material for AC to improve the heat transfer performance, while the mass transfer performance should be considered in different conditions for utilization of adsorbent.

关键词： permeability     thermal conductivity     expanded nature graphite     activated carbon    

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Effects of nitrate concentration on biological hydrogen production by mixed cultures

Bo WANG, Wei WAN, Jianlong WANG,

《环境科学与工程前沿（英文）》 2009年 第3卷 第4期   页码 380-386 doi: 10.1007/s11783-009-0142-0

摘要： The effects of nitrate on fermentative hydrogen production and soluble metabolites from mixed cultures were investigated by varying nitrate concentrations from 0 to 10g N/L at 35°C with an initial pH of 7.0. The results showed that the substrate degradation rate, hydrogen production potential, hydrogen yield, and average hydrogen production rate initially increased with increasing nitrate concentrations from 0 to 0.1g N/L, while they decreased with increasing nitrate concentrations from 0.1 to 10g N/L. The maximum hydrogen production potential of 305.0mL, maximum hydrogen yield of 313.1mL/g glucose, and maximum average hydrogen production rate of 13.3mL/h were obtained at a nitrate concentration of 0.1g N/L. The soluble metabolites produced by the mixed cultures contained only ethanol and acetic acid (HAc) without propionic acid (HPr) and butyric acid (HBu). This study used the Modified Logistic model to describe the progress of cumulative hydrogen production in batch tests. A concise model was proposed to describe the effects of nitrate concentration on average hydrogen production rate.

关键词： nitrogen source     biohydrogen     fermentative hydrogen production     quantitative kinetic model    

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Linear and nonlinear elastic analysis of closely spaced strip foundations using Pasternak model

Priyanka GHOSH, S. RAJESH, J. SAI CHAND

《结构与土木工程前沿（英文）》 2017年 第11卷 第2期   页码 228-243 doi: 10.1007/s11709-016-0370-x

摘要： In this study, an attempt is made to determine the interaction effect of two closely spaced strip footings using Pasternak model. The study considers small strain problem and has been performed using linear as well as nonlinear elastic analysis to determine the interaction effect of two nearby strip footings. The hyperbolic stress-strain relationship has been considered for the nonlinear elastic analysis. The linear elastic analysis has been carried out by deriving the equations for the interference effect of the footings in the framework of Pasternak model equation; whereas, the nonlinear elastic analysis has been performed using the finite difference method to solve the second order nonlinear differential equation evolved from Pasternak model with proper boundary conditions. Results obtained from the linear and the nonlinear elastic analysis are presented in terms of non-dimensional interaction factors by varying different parameters like width of the foundation, load on the foundation and the depth of the rigid base. Results are suitably compared with the existing values in the literature.

关键词： bearing capacity     linear and non-linear elasticity     foundation     interaction effect     numerical modeling     Pasternak model    

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基于迭代方法的联合压缩感知与相位修正多站外辐射源雷达成像算法研究 None

Jue WANG, Jun WANG

《信息与电子工程前沿（英文）》 2018年 第19卷 第4期   页码 557-568 doi: 10.1631/FITEE.1601423

摘要： 受限于机会照射源信号通常为窄带信号，多站外辐射源雷达成像系统分辨率通常较低。另外，由于跟踪系统精度影响及站址测量过程中存在测量误差，系统成像质量会严重下降。为提高多站外辐射源雷达成像系统成像性能，开展了基于层析成像原理的高分辨外辐射源雷达成像算法研究。进一步，将压缩感知技术应用于外辐射源雷达成像系统中，以改善系统成像分辨力。最后，针对非合作平台测量误差引入的相位误差，提出相应的外辐射源雷达成像系统相位补偿方法。通过最小化图像的重构误差建立了相位误差求解模型，基于定点迭代技术对相位误差模型求解。所提相位误差补偿技术是一种非参数化方法，可用于补偿任意形式相位误差。理论分析与仿真实验验证了所提方法的有效性和收敛性。

关键词： 多站外辐射源雷达；压缩感知；相位修正；定点迭代技术    

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标题 作者 时间 类型 操作

Genome-wide association study of the backfat thickness trait in two pig populations

Dandan ZHU,Xiaolei LIU,Rothschild MAX,Zhiwu ZHANG,Shuhong ZHAO,Bin FAN

期刊论文

A rain-on-snow mixed flood forecast model and its application

Jian WU, Lan LI,

期刊论文

General expression for linear and nonlinear time series models

Ren HUANG, Feiyun XU, Ruwen CHEN

期刊论文

基于网络图拓扑结构的MILP模型求解智能制造系统中的工艺规划问题

刘齐浩, 李新宇, 高亮

期刊论文

Comparison between linear and non-linear forms of pseudo-first-order and pseudo-second-order adsorption

Junxiong LIN , Lan WANG ,

期刊论文

An assemble-to-order production planning with the integration of order scheduling and mixed-model sequencing

Baoxi WANG, Zailin GUAN, Yarong CHEN, Xinyu SHAO, Ming JIN, Chaoyong ZHANG

期刊论文

Cutting CO emissions through demand side regulation: Implications from multi-regional input–output linearprogramming model

期刊论文

使用数据驱动模型优化抗体纯化策略

刘松崧, Lazaros G. Papageorgiou

期刊论文

A new approach for scheduling of multipurpose batch processes with unlimited intermediate storage policy

Nikolaos Rakovitis, Nan Zhang, Jie Li, Liping Zhang

期刊论文

Model reduction techniques for dynamics analysis of ultra-precision linear stage

Xuedong CHEN, Zhixin LI

期刊论文

Multi-objective optimization for the multi-mode finance-based project scheduling problem

Sameh Al-SHIHABI, Mohammad AlDURGAM

期刊论文

Permeability and thermal conductivity of host compressed natural graphite for consolidated activated

Bo TIAN, Liwei WANG, Zhequan JIN, Ruzhu WANG

期刊论文

Effects of nitrate concentration on biological hydrogen production by mixed cultures

Bo WANG, Wei WAN, Jianlong WANG,

期刊论文

Linear and nonlinear elastic analysis of closely spaced strip foundations using Pasternak model

Priyanka GHOSH, S. RAJESH, J. SAI CHAND

期刊论文

基于迭代方法的联合压缩感知与相位修正多站外辐射源雷达成像算法研究

Jue WANG, Jun WANG

期刊论文