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主动式队列管理；传输控制协议；往返时滞；史密斯预估器 1

交流永磁同步电机；滑模控制器；扩张状态观测器；鲁棒控制；运动控制 1

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Robust switched fractional controller for performance improvement of single phase active power filter

H. AFGHOUL,F. KRIM,D. CHIKOUCHE,A. BEDDAR

《能源前沿（英文）》 2016年 第10卷 第2期   页码 203-212 doi: 10.1007/s11708-015-0381-7

摘要： A novel controller is proposed to regulate the DC-link voltage of a single phase active power filter (SPAPF). The proposed switched fractional controller (SFC) consists of a conventional PI controller, a fractional order PI (FO-PI) controller and a decision maker that switches between them. Commonly, the conventional PI controller is used in regulation loops due to its advantages in steady-state but it is limited in transient state. On the other hand, the FO-PI controller overcomes these drawbacks but it causes dramatic degradation in control performances in steady-state because of the fractional calculus theory and the approximation method used to implement this kind of controller. Thus, the purpose of this paper is to switch to the PI controller in steady-state to obtain the best power quality and to switch to the FO-PI controller when external disturbances are detected to guarantee a fast transient state. To investigate the efficiency and accuracy of the SFC considering all robustness tests, an experimental setup has been established. The results of the SFC fulfill the requirements, confirm its high performances in steady and transient states and demonstrate its feasibility and effectiveness. The experiment results have satisfied the limit specified by the IEEE harmonic standard 519.

关键词： conventional PI controller     fractional calculus (FC)     total harmonic distortion (THD)     Oustaloup continuous approximation (OCA)     single phase active power filter (SPAPF)    

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Bandwidth-limited active suspension controller for an off-road vehicle based on co-simulation technology

FENG Jinzhi, ZHENG Songlin, YU Fan

《机械工程前沿（英文）》 2008年 第3卷 第1期   页码 111-117 doi: 10.1007/s11465-008-0020-7

摘要： This paper presents the design process of a controller for bandwidth-limited active hydro-pneumatic suspension employed by an off-road vehicle based on co-simulation technology. First, a detailed multi-body dynamic model of the vehicle is established by using the ADAMS/View software package, which is followed by validation using a vehicle field test. Second, a combined PID and fuzzy controller is designed for the bandwidth-limited active suspension system and then programmed by means of S-functions in Matlab/Simulink, to which a data exchange interface with ADAMS/View is also defined. Third, the proposed control algorithm is implemented on the multi-body dynamic vehicle model to enable the co-simulation to run repeatedly until a more practical controller is achieved. In the end, the proposed active suspension system is compared with a conventional passive system. Simulation results show that the proposed active suspension system considerably improves both the ride and handling performance of the vehicle and therefore increases the maximum traveling speeds even on rough roads.

关键词： co-simulation technology     exchange interface     conventional     bandwidth-limited     algorithm    

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Performance of PI controller for control of active and reactive power in DFIG operating in a grid-connected

Azzouz TAMAARAT,Abdelhamid BENAKCHA

《能源前沿（英文）》 2014年 第8卷 第3期   页码 371-378 doi: 10.1007/s11708-014-0318-6

摘要： Due to several factors, wind energy becomes an essential type of electricity generation. The share of this type of energy in the network is becoming increasingly important. The objective of this work is to present the modeling and control strategy of a grid connected wind power generation scheme using a doubly fed induction generator (DFIG) driven by the rotor. This paper is to present the complete modeling and simulation of a wind turbine driven DFIG in the second mode of operating (the wind turbine pitch control is deactivated). It will introduce the vector control, which makes it possible to control independently the active and reactive power exchanged between the stator of the generator and the grid, based on vector control concept (with stator flux or voltage orientation) with classical PI controllers. Various simulation tests are conducted to observe the system behavior and evaluate the performance of the control for some optimization criteria (energy efficiency and the robustness of the control). It is also interesting to play on the quality of electric power by controlling the reactive power exchanged with the grid, which will facilitate making a local correction of power factor.

关键词： wind power     doubly fed induction generator (DFIG)     vector control     active power     reactive power     maximum power point tracking (MPPT)    

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纳卫星微型百叶窗热控技术研究及仿真

杨娟,李运泽,王浚

《中国工程科学》 2008年 第10卷 第7期   页码 169-172

摘要： 在球状纳卫星动态特性模型的基础上，提出了一种模 糊PI 混合控制方法。分别在舱内仪器散热增加和减少的工况下进行控制仿真。

关键词： 纳卫星     微型百叶窗     模糊PI 控制器     仿真    

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Structural parameter design method for a fast-steering mirror based on a closed-loop bandwidth

Guozhen CHEN, Pinkuan LIU, Han DING

《机械工程前沿（英文）》 2020年 第15卷 第1期   页码 55-65 doi: 10.1007/s11465-019-0545-y

摘要： When a fast-steering mirror (FSM) system is designed, satisfying the performance requirements before fabrication and assembly is vital. This study proposes a structural parameter design approach for an FSM system based on the quantitative analysis of the required closed-loop bandwidth. First, the open-loop transfer function of the FSM system is derived. In accordance with the transfer function, the notch filter and proportional-integral (PI) feedback controller are designed as a closed-loop controller. The gains of the PI controller are determined by maximizing the closed-loop bandwidth while ensuring the robustness of the system. Then, the two unknown variables of rotational radius and stiffness in the open-loop transfer function are optimized, considering the bandwidth as a constraint condition. Finally, the structural parameters of the stage are determined on the basis of the optimized results of rotational radius and stiffness. Simulations are conducted to verify the theoretical analysis. A prototype of the FSM system is fabricated, and corresponding experimental tests are conducted. Experimental results indicate that the bandwidth of the proposed FSM system is 117.6 Hz, which satisfies the minimum bandwidth requirement of 100 Hz.

关键词： fast-steering mirror     structural parameter     PI controller     bandwidth     notch filter    

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基于队列智能方法的分数阶PIλDμ控制器设计 None

Pritesh SHAH, Sudhir AGASHE, Anand J. KULKARNI

《信息与电子工程前沿（英文）》 2018年 第19卷 第3期   页码 437-445 doi: 10.1631/FITEE.1601495

摘要： 近年来，队列智能方法逐步演变为一种基于人工智能的优化方法。本文首次采用队列智能方法对分数阶PID控制器的参数进行优化。验证了队列智能方法在分数阶PID控制器设计中的性能，并与其他方法如粒子群优化方法、遗传算法和改进的电磁算法等的性能进行比较。结果表明，与其它3种算法相比，队列智能方法在代价函数、计算时间和函数评估方面表现出更好性能。此外，队列智能方法对应的标准差表明，提出的方法在解决控制问题时具有鲁棒性。

关键词： 队列智能；分数阶微积分；分数阶PID控制器；调节    

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Telomeric impact of conventional chemotherapy

null

《医学前沿（英文）》 2013年 第7卷 第4期   页码 411-417 doi: 10.1007/s11684-013-0293-z

摘要：

The increased level of chromosome instability in cancer cells, leading to aneuploidy and gross chromosomal rearrangements, is not only a driving force for oncogenesis but also can be the Achille’s heel of the disease since many chemotherapies (CT) kill cells by inducing a non-tolerable rate of DNA damage. A wealth of published evidence showed that telomere stability can be more affected than the bulk of the genome by several conventional antineoplasic drugs. These results raise the interesting possibility that CT with genotoxic drugs preferentially target telomeres. In agreement with this view, accelerated shortening of telomere length has been described in blood lineage cells following high-dose CT (stem cell transplantation) or non-myeloablative CT. However, almost nothing is known on the consequences of this shortening in terms of telomere stability, senescence and on the development of second cancers or post-treatment aging-like syndromes in cancer survivors (cognitive defect, fertility impairment, etc.). In this article, we propose: (1) telomeres of cancer cells are preferential genomic targets of chemotherapies altering chromosome maintenance; (2) telomere functional parameters can be a surrogate marker of chemotherapy sensitivity and toxicity; (3) the use of anti-telomere molecule could greatly enhance the sensitivity to standards chemotherapies.

关键词： telomere     antineoplasic drugs     conventional chemotherapies    

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4Pi荧光超分辨显微术综述 Review

郝翔, 李依明, 傅爽, 李旸晖, 许迎科, 匡翠方, 刘旭

《工程（英文）》 2022年 第11卷 第4期   页码 146-153 doi: 10.1016/j.eng.2020.07.028

摘要： 回顾这些历程，一个重要的里程碑是基于两个对置物镜的4Pi 显微架构及其超分辨版本的出现。鉴于此，本文综述了4Pi 超分辨显微术的近期进展。总体上，4Pi 超分辨显微镜为透明样品观测提供了一
种能够突破衍射极限、非侵入、各向同性的三维分辨率的技术手段。具体而言，本文针对目标开关和随机开关两个主要4Pi 超分辨显微术版本，讨论了它们的架构、原理、应用和未来发展趋势。

关键词： 荧光超分辨显微术     超分辨成像     4Pi超分辨显微术     isoSTED     4Pi-SMLM    

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RGS16 regulated by let-7c-5p promotes glioma progression by activating PI3K-AKT pathway

《医学前沿（英文）》 2023年 第17卷 第1期   页码 143-155 doi: 10.1007/s11684-022-0929-y

摘要： Gliomas are the most common central nervous system tumours; they are highly aggressive and have a poor prognosis. RGS16 belongs to the regulator of G-protein signalling (RGS) protein family, which plays an important role in promoting various cancers, such as breast cancer, pancreatic cancer, and colorectal cancer. Moreover, previous studies confirmed that let-7c-5p, a well-known microRNA, can act as a tumour suppressor to regulate the progression of various tumours by inhibiting the expression of its target genes. However, whether RGS16 can promote the progression of glioma and whether it is regulated by miR let-7c-5p are still unknown. Here, we confirmed that RGS16 is upregulated in glioma tissues and that high expression of RGS16 is associated with poor survival. Ectopic deletion of RGS16 significantly suppressed glioma cell proliferation and migration both in vitro and in vivo. Moreover, RGS16 was validated as a direct target gene of miR let-7c-5p. The overexpression of miR let-7c-5p obviously downregulated the expression of RGS16, and knocking down miR let-7c-5p had the opposite effect. Thus, we suggest that the suppression of RGS16 by miR let-7c-5p can promote glioma progression and may serve as a potential prognostic biomarker and therapeutic target in glioma.

关键词： RGS16     let-7c-5p     glioma     proliferation     migration    

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用于非线性混沌系统的基于分岔分数阶PID控制器设计方法 None

Karima RABAH, Samir LADACI, Mohamed LASHAB

《信息与电子工程前沿（英文）》 2018年 第19卷 第2期   页码 180-191 doi: 10.1631/FITEE.1601543

摘要： 提出一个新的鲁棒分数阶比例-积分-微分（FOPID）控制器，以其中一个不稳定的固定点来稳定一个扰动非线性混沌系统。基于使用分岔图的比例-积分-微分行为，分析非线性混沌系统的稳定性。提取控制器参数的初始集，其后续可通过二次准则优化。积分和微分分数阶也被二次准则识别。在两个非线性系统（陈氏多涡卷混沌系统和Genesio-Tesi混沌系统）中应用数值模拟，结果表明分数阶比例-积分-微分控制器在稳定非稳定固定点过程中，甚至在随机扰动情况下，能够提供最好的闭环系统性能。

关键词： 分数阶系统；分岔图；分数PID控制器；陈氏多涡卷混沌系统；Genesio-Tesi混沌系统    

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Oxygen reduction electrocatalysis: From conventional to single-atomic platinum-based catalysts for proton

《能源前沿（英文）》 2024年 第18卷 第2期   页码 206-222 doi: 10.1007/s11708-023-0907-3

摘要： Platinum (Pt)-based materials are still the most efficient and practical catalysts to drive the sluggish kinetics of cathodic oxygen reduction reaction (ORR) in proton exchange membrane fuel cells (PEMFCs). However, their catalysis and stability performance still need to be further improved in terms of corrosion of both carbon support and Pt catalyst particles as well as Pt loading reduction. Based on the developed synthetic strategies of alloying/nanostructuring Pt particles and modifying/innovating supports in developing conventional Pt-based catalysts, Pt single-atom catalysts (Pt SACs) as the recently burgeoning hot materials with a potential to achieve the maximum utilization of Pt are comprehensively reviewed in this paper. The design thoughts and synthesis of various isolated, alloyed, and nanoparticle-contained Pt SACs are summarized. The single-atomic Pt coordinating with non-metals and alloying with metals as well as the metal-support interactions of Pt single-atoms with carbon/non-carbon supports are emphasized in terms of the ORR activity and stability of the catalysts. To advance further research and development of Pt SACs for viable implementation in PEMFCs, various technical challenges and several potential research directions are outlined.

关键词： oxygen reduction electrocatalysis     Pt single-atom catalysts     conventional Pt-based catalysts     design thoughts and synthesis     metal-support interactions    

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Xiao Ke Qing improves glycometabolism and ameliorates insulin resistance by regulating the PI3K/Akt pathway

Xiaoqing Li, Xinxin Li, Genbei Wang, Yan Xu, Yuanyuan Wang, Ruijia Hao, Xiaohui Ma

《医学前沿（英文）》 2018年 第12卷 第6期   页码 688-696 doi: 10.1007/s11684-018-0662-8

摘要：

Xiao Ke Qing (XKQ) granule has been clinically used to treat type 2 diabetes mellitus (T2DM) for 10 years in Chinese traditional medication. However, its mechanisms against hyperglycemia remain poorly understood. This study aims to investigate XKQ mechanisms on diabetes and diabetic liver disease by using the KKAy mice model. Our results indicate that XKQ can significantly reduce food and water intake. XKQ treatment also remarkably decreases both the fasting blood glucose and blood glucose in the oral glucose tolerance test. Additionally, XKQ can significantly decrease the serum alanine aminotransferase level and liver index and can alleviate the fat degeneration in liver tissues. Moreover, XKQ can ameliorate insulin resistance and upregulate the expression of IRS-1, PI3K (p85), p-Akt, and GLUT4 in the skeletal muscle of KKAy mice. XKQ is an effective drug for T2DM by ameliorating insulin resistance and regulating the PI3K/Akt signaling pathway in the skeletal muscle.

关键词： XKQ     type 2 diabetes mellitus     KKAy mice     PI3K/Akt pathway     diabetic liver disease    

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Esophageal pulse oximetry is more accurate and detects hypoxemia earlier than conventional pulse oximetry

null

《医学前沿（英文）》 2012年 第6卷 第4期   页码 406-410 doi: 10.1007/s11684-012-0217-3

摘要：

The esophagus is perfused directly by prominent arteries and may provide a more consistent tissue source for pulse oximetry. The goal of this study was to evaluate the sensitivity and accuracy of an esophageal pulse oximetry probe on patients during controlled hypoxemia in comparison to measurements obtained with conventional pulse oximetry (SpulseO2). Forty-five ASA I–II adult patients were included in this prospective observational study. Nellcor digital oximetric probes were placed on finger tips for SpulseO2 before anesthesia. After tracheal intubation, an esophageal probe was placed in the lower segment of the esophagus for esophageal oximetric monitoring (SoesO2). All patients were disconnected from the breathing circuit to establish a controlled hypoxemia, and were re-connected to the breathing circuit and ventilated with 100% oxygen immediately when SoesO2 dropped to 90%. Matched SoesO2 and SpulseO2 readings were recorded when SoesO2measurements were at 100%, 95%, 90% and the lowest reading. The time for SoesO2 and SpulseO2 to drop from 100% to 95%, 90% and return to 100% was recorded. Oxygen saturation from arterial blood samples (SartO2) was also measured at each time point respectively. The linear correlation coefficient of the regression analysis between SartO2 and SoesO2 was 0.954. The mean±2SD of the difference was 0.3%±4.3% for SoesO2vs. SartO2 and 6.8%±5.6% for SpulseO2vs. SartO2 (P<0.001). The 95% confidence interval for the absolute difference between SoesO2 and SartO2 was 0.3% to 0.7% and 6.2% to 7.4% between SpulseO2 and SartO2. The time to reach 90% saturation measured with SoesO2 was approximately 94 seconds earlier than the SpulseO2 (P<0.001). In conclusion, SoesO2 is more accurate and enables earlier detection of hypoxemia when compared to conventional pulse oximetry during hypoxemia for patients undergoing general anesthesia.

关键词： esophageal pulse oximetry     conventional pulse oximetry     hypoxemia    

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Ultraviolet-B induced expression of hypoxia-inducible factor 1α, transferrin receptor through EGFR/PI3K

LI Yanhua, BI Zhigang

《医学前沿（英文）》 2007年 第1卷 第1期   页码 79-86 doi: 10.1007/s11684-007-0016-4

摘要： The aim of this research was to explore the effects and signaling pathway of ultraviolet-B (UVB) irradiation on the expression of hypoxia-inducible factor 1α (HIF-1α) and transferrin receptor (TfR). HIF-1α protein was measured by Western blot method. Expressions of epidermal growth factor receptor (EGFR), phosphor-EGF-R and TfR after UVB irradiation were determined with flow cytometry. After UVB irradiation, mRNA levels of HIF-1α and TfR were detected by real time-PCR. Results showed that compared with control groups, UVB was able to induce HIF1α and TfR protein expression in a dose- and time-dependent manner in HaCat cells (<0.05). TfR mRNA was expressed in a dose-dependent manner and reached a peak at the 8th hour in HaCat cells (<0.05) whereas HIF-1α mRNA expression was not affected by UVB treatment (>0.05). The EGFR/PI3K/AKT signaling pathway was required for the induction of HIF-1α and TfR expression induced by UVB. UVB induced activation of EGFR in HaCat cells and EGFR regulated expression of TfR and HIF-1α. EGFR (-/-) MEF did not increase the HIF1 expression following UVB irradiation (>0.05). In contrast, EGFR (+/+) MEF strongly enhanced HIF1α expression after UVB irradiation (<0.05). PD153035, a selective inhibitor of EGFR tyrosine kinase, inhibited the TfR protein expression in UVB-treated cells in a dose-dependent manner (P<0.05). PI3K inhibitors, LY294002 and wortmannin, inhibited HIF-1? and TfR expressions induced by UVB (P<0.05). The DEC1 (-/-) Ha-Cat cells did not increase their TfR and HIF-1α expressions following UVB irradiation (>0.05). In contrast, DEC1 (+/+) HaCat cells strongly enhanced TfR and HIF-1? protein expression after UVB irradiation (P<0.05). We conclude that UVB induces TfR and HIF-1αexpressions via EGFR/PI3K/AKT/DEC1 signaling pathway.
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Techno-economic characteristics of wastewater treatment plants retrofitted from the conventional activated

《环境科学与工程前沿（英文）》 doi: 10.1007/s11783-021-1483-6

摘要：

While a growing number of wastewater treatment plants (WWTPs) are being retrofitted from the conventional activated sludge (CAS) process to the membrane bioreactor (MBR) process, the debate on the techno-economy of MBR vs. CAS has continued and calls for a thorough assessment based on techno-economic valuation.

关键词： Membrane bioreactor (MBR)     Conventional activated sludge (CAS)     Cost-benefit analysis     Data envelopment analysis     Net profit    

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标题 作者 时间 类型 操作

Robust switched fractional controller for performance improvement of single phase active power filter

H. AFGHOUL,F. KRIM,D. CHIKOUCHE,A. BEDDAR

期刊论文

Bandwidth-limited active suspension controller for an off-road vehicle based on co-simulation technology

FENG Jinzhi, ZHENG Songlin, YU Fan

期刊论文

Performance of PI controller for control of active and reactive power in DFIG operating in a grid-connected

Azzouz TAMAARAT,Abdelhamid BENAKCHA

期刊论文

纳卫星微型百叶窗热控技术研究及仿真

杨娟,李运泽,王浚

期刊论文

Structural parameter design method for a fast-steering mirror based on a closed-loop bandwidth

Guozhen CHEN, Pinkuan LIU, Han DING

期刊论文

基于队列智能方法的分数阶PIλDμ控制器设计

Pritesh SHAH, Sudhir AGASHE, Anand J. KULKARNI

期刊论文

Telomeric impact of conventional chemotherapy

null

期刊论文

4Pi荧光超分辨显微术综述

郝翔, 李依明, 傅爽, 李旸晖, 许迎科, 匡翠方, 刘旭

期刊论文

RGS16 regulated by let-7c-5p promotes glioma progression by activating PI3K-AKT pathway

期刊论文

用于非线性混沌系统的基于分岔分数阶PID控制器设计方法

Karima RABAH, Samir LADACI, Mohamed LASHAB

期刊论文

Oxygen reduction electrocatalysis: From conventional to single-atomic platinum-based catalysts for proton

期刊论文

Xiao Ke Qing improves glycometabolism and ameliorates insulin resistance by regulating the PI3K/Akt pathway

Xiaoqing Li, Xinxin Li, Genbei Wang, Yan Xu, Yuanyuan Wang, Ruijia Hao, Xiaohui Ma

期刊论文

Esophageal pulse oximetry is more accurate and detects hypoxemia earlier than conventional pulse oximetry

null

期刊论文

Ultraviolet-B induced expression of hypoxia-inducible factor 1α, transferrin receptor through EGFR/PI3K

LI Yanhua, BI Zhigang

期刊论文

Techno-economic characteristics of wastewater treatment plants retrofitted from the conventional activated

期刊论文