资源类型

期刊论文 2

年份

2020 1

2007 1

关键词

检索范围:

排序: 展示方式:

Diporphyrin tweezer for multichannel spectroscopic analysis of enantiomeric excess

Daniel T. Payne, Mandeep K. Chahal, Václav Březina, Whitney A. Webre, Katsuhiko Ariga, Francis D’Souza, Jan Labuta, Jonathan P. Hill

《化学科学与工程前沿(英文)》 2020年 第14卷 第1期   页码 28-40 doi: 10.1007/s11705-019-1869-1

摘要: Chiral 1,1’-binaphthyl-linked diporphyrin ‘tweezers’ ( )- /( )- and the corresponding zinc(II) complexes ( )- /( )- were prepared as chiral host molecules, and their utility for chiral analyses (especially enantiomeric excess ( ) determinations) were evaluated. Tris(1- -dodecyl)porphyrins were used for the first time as the interacting units. Host capabilities of the diporphyrin tweezers were investigated by titrations with ( , )- and ( , )-cyclohexane-1,2-diamine (CHDA). The host molecules could be used as multichannel probes of by using UV-vis, circular dichroism (CD), fluorescence emission and H nuclear magnetic resonance ( H-NMR) methods. Chiral configurations could also be differentiated using CD or H-NMR spectroscopy. All three optical techniques give good resolution of with reasonable sensitivity considering the low concentrations used (ca. 10 mol·L ). The determination of CHDA enantiomers using NMR spectroscopy is also possible because of the reasonably well separated resonances in the case of ( , )- and ( , )-CHDA. Non-metallated ( )- /( )- hosts could not be used to detect chiral information in a strongly acidic chiral guest. This work demonstrates the utility of 1,1’-binapthyl-linked chiral hosts for chiral analysis of ditopically interacting enantiomers.

关键词: porphyrin dimer     chirality     enantiomeric excess     CD     fluorescence    

Isolation of microbe for asymmetric reduction of prochiral aromatic ketone and its reaction characters

YANG Zhonghua, WANG Yu, WANG Guanghui, ZENG Rong, YAO Shanjing

《化学科学与工程前沿(英文)》 2007年 第1卷 第4期   页码 416-420 doi: 10.1007/s11705-007-0076-7

摘要: The favorable microbes for the asymmetric reduction of prochiral aromatic ketones was isolated from soil using acetophenone as the sole carbon source, when the asymmetric reduction of acetophenone (ACP) to chiral ?-phenethyl alcohol (PEA) was chosen as the model reaction. Two microbe strains with excellent catalytic activity were obtained. They were and identified by bacteria identification. The product of the asymmetric reduction of ACP catalyzed by was mainly R-PEA and that by was mainly S-PEA. The yield and enantiomeric excesses (e.e.) could respectively reach 75% and 90% for , and 80% and 70% for , much higher than those catalyzed by baker s yeast.

关键词: excellent catalytic     prochiral aromatic     enantiomeric     -phenethyl     catalytic activity    

标题 作者 时间 类型 操作

Diporphyrin tweezer for multichannel spectroscopic analysis of enantiomeric excess

Daniel T. Payne, Mandeep K. Chahal, Václav Březina, Whitney A. Webre, Katsuhiko Ariga, Francis D’Souza, Jan Labuta, Jonathan P. Hill

期刊论文

Isolation of microbe for asymmetric reduction of prochiral aromatic ketone and its reaction characters

YANG Zhonghua, WANG Yu, WANG Guanghui, ZENG Rong, YAO Shanjing

期刊论文