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Mengshi LIN,
《化学科学与工程前沿(英文)》 2009年 第3卷 第4期 页码 427-435 doi: 10.1007/s11705-009-0244-z
关键词: milk-derived Melamine labor-intensive cyanurate time-consuming
《环境科学与工程前沿(英文)》 2022年 第16卷 第10期 doi: 10.1007/s11783-022-1541-8
● Perfluorooctanesulfonic acid and perfluorooctanoic acid highest in human milk.
关键词: Human biomonitoring Human breast milk LC-MS/MS analysis Lifestyle parameters
Global warming potential associated with Irish milk powder production
William Finnegan, Jamie Goggins, Aksana Chyzheuskaya, Xinmin Zhan
《环境科学与工程前沿(英文)》 2017年 第11卷 第3期 doi: 10.1007/s11783-017-0949-z
关键词: Dairy Global warming potential Ireland Life cycle assessment Milk powder Milk production
Expression of recombinant human butyrylcholinesterase in the milk of transgenic mice
Dan LU,Shengzhe SHANG,Shen LIU,Ying WU,Fangfang WU,Tan TAN,Qiuyan LI,Yunping DAI,Xiaoxiang HU,Yaofeng ZHAO,Ning LI
《农业科学与工程前沿(英文)》 2014年 第1卷 第3期 页码 179-184 doi: 10.15302/J-FASE-2014020
关键词: recombinant human butyrylcholinesterase (rhBCHE) human lactoferrin bacterial artificial chromosome (hLF BAC) transgenic mice milk
CH4 and N2O emissions from double-rice cropping system as affected by Chinese milk
Heshui XU,Dengyun LI,Bo ZHU,Kai ZHANG,Yadong YANG,Chen WANG,Ying JIANG,Zhaohai ZENG
《农业科学与工程前沿(英文)》 2017年 第4卷 第1期 页码 59-68 doi: 10.15302/J-FASE-2017137
关键词: Chinese milk vetch CH4 double-rice cropping system grain yield N2O rice straw
Tuning porosity of coal-derived activated carbons for CO2 adsorption
《化学科学与工程前沿(英文)》 2022年 第16卷 第9期 页码 1345-1354 doi: 10.1007/s11705-022-2155-1
关键词: coal-derived activated carbons porosity CO2 adsorption molecular dynamics
《医学前沿(英文)》 2023年 第17卷 第3期 页码 534-548 doi: 10.1007/s11684-022-0953-y
关键词: autoimmune hepatitis (AIH) concanavalin A (Con A) human menstrual blood-derived stem cells (MenSCs) apoptosis mitogen-activated protein kinase (MAPK)
Microorganism-derived biological macromolecules for tissue engineering
《医学前沿(英文)》 2022年 第16卷 第3期 页码 358-377 doi: 10.1007/s11684-021-0903-0
关键词: biological macromolecules regenerative medicine tissue engineering exopolysaccharide carbohydrate
null
《医学前沿(英文)》 2016年 第10卷 第1期 页码 104-110 doi: 10.1007/s11684-016-0432-4
Advances in next-generation sequencing and bioinformatics have begun to reveal the complex genetic landscape in human cancer genomes, including oral squamous cell carcinoma (OSCC). Sophisticated preclinical models that fully represent intra- and inter-tumoral heterogeneity are required to understand the molecular diversity of cancer and achieve the goal of personalized therapies. Patient-derived xenograft (PDX) models generated from human tumor samples that can retain the histological and genetic features of their donor tumors have been shown to be the preferred preclinical tool in translational cancer research compared with other conventional preclinical models. Specifically, genetically well-defined PDX models can be applied to accelerate targeted antitumor drug development and biomarker discovery. Recently, we have successfully established and characterized an OSCC PDX panel as part of our tumor bio-bank for translational cancer research. In this paper, we discuss the establishment, characterization, and preclinical applications of the PDX models. In particular, we focus on the classification and applications of the PDX models based on validated annotations, including clinicopathological features, genomic profiles, and pharmacological testing information. We also explore the translational value of this well-annotated PDX panel in the development of co-clinical trials for patient stratification and treatment optimization in the near future. Although various limitations still exist, this preclinical approach should be further tested and improved.
关键词: patient-derived xenograft models personalized medicine co-clinical trial patient stratification oral squamous cell carcinoma
Ultimate bearing capacity of strip footing resting on clay soil mixed with tire-derived aggregates
《结构与土木工程前沿(英文)》 2021年 第15卷 第4期 页码 1016-1024 doi: 10.1007/s11709-021-0751-7
关键词: kaolin physical modeling tests stabilization numerical modeling
Fabrication of coconut shell-derived porous carbons for CO adsorption application
《化学科学与工程前沿(英文)》 2023年 第17卷 第8期 页码 1122-1130 doi: 10.1007/s11705-022-2292-6
关键词: porous carbons CO2 adsorption KOH activation single step reaction biomass
Preparation of biomass-derived carbon loaded with MnO as lithium-ion battery anode for improving its
《化学科学与工程前沿(英文)》 2023年 第18卷 第1期 doi: 10.1007/s11705-023-2376-y
关键词: biomass-derived carbon MnO2 lithium-ion batteries anode material high reversible capacity
Catalytic conversion of biomass-derived compounds to various amino acids: status and perspectives
《化学科学与工程前沿(英文)》 2023年 第17卷 第7期 页码 817-829 doi: 10.1007/s11705-022-2254-z
关键词: biomass amino acids chitin nitrogen-containing compounds lignocellulose
Expression of PC-cell-derived growth factor in breast cancer
Haiping SONG MD, Lan SHI MD, Chunping LIU MD, Tao HUANG MD,
《医学前沿(英文)》 2009年 第3卷 第4期 页码 426-430 doi: 10.1007/s11684-009-0085-7
关键词: PC-cell-derived growth factor breast neoplasms clinical markers
null
《医学前沿(英文)》 2012年 第6卷 第4期 页码 411-415 doi: 10.1007/s11684-012-0226-2
Ketamine exerts rapid and robust antidepressant properties in both animal models and depressed patients and tramadol possesses potential antidepressant effects. Brain-derived neurotrophic factor (BDNF) is an important biomarker for mood disorders and tropomyosin-related kinase B (TrkB) is a high affinity catalytic receptor for BDNF. We hypothesized that tramadol pretreatment might reinforce ketamine-elicited antidepressant effects with significant changes in hippocampal BDNF and TrkB levels in rats. Immobility time of rats receiving different treatment in the forced swimming test (FST) was observed. Levels of BDNF and TrkB in hippocampus were measured by enzyme linked immunosorbent assay. Results showed that tramadol (5 mg/kg) administrated alone neither elicited antidepressant effects nor altered BDNF or TrkB level. However, pretreatment with tramadol (5 mg/kg) enhanced the ketamine (10 mg/kg) -elicited antidepressant effects and upregulated the BDNF and TrkB levels in hippocampus. In conclusion, tramadol pretreatment reinforces the ketamine-elicited antidepressant effects, which is associated with the increased levels of BDNF and TrkB in rat hippocampus.
关键词: tramadol ketamine antidepressant brain-derived neurotrophic factor tropomyosin-related kinase B
标题 作者 时间 类型 操作
A review of traditional and novel detection techniques for melamine and its analogues in foods and animal feed
Mengshi LIN,
期刊论文
Perfluoroalkane acids in human milk under the global monitoring plan of the Stockholm Convention on Persistent
期刊论文
Global warming potential associated with Irish milk powder production
William Finnegan, Jamie Goggins, Aksana Chyzheuskaya, Xinmin Zhan
期刊论文
Expression of recombinant human butyrylcholinesterase in the milk of transgenic mice
Dan LU,Shengzhe SHANG,Shen LIU,Ying WU,Fangfang WU,Tan TAN,Qiuyan LI,Yunping DAI,Xiaoxiang HU,Yaofeng ZHAO,Ning LI
期刊论文
CH4 and N2O emissions from double-rice cropping system as affected by Chinese milk
Heshui XU,Dengyun LI,Bo ZHU,Kai ZHANG,Yadong YANG,Chen WANG,Ying JIANG,Zhaohai ZENG
期刊论文
Human menstrual blood-derived stem cells alleviate autoimmune hepatitis via JNK/MAPK signaling pathway
期刊论文
Patient-derived xenograft platform of OSCC: a renewable human bio-bank for preclinical cancer research
null
期刊论文
Ultimate bearing capacity of strip footing resting on clay soil mixed with tire-derived aggregates
期刊论文
Preparation of biomass-derived carbon loaded with MnO as lithium-ion battery anode for improving its
期刊论文
Catalytic conversion of biomass-derived compounds to various amino acids: status and perspectives
期刊论文
Expression of PC-cell-derived growth factor in breast cancer
Haiping SONG MD, Lan SHI MD, Chunping LIU MD, Tao HUANG MD,
期刊论文