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A PLATFORM TO AID SELECT THE OPTIMAL TOOL TO DESIGN GUIDE RNAS

《农业科学与工程前沿(英文)》   页码 296-305 doi: 10.15302/J-FASE-2022479

摘要:

● Summaries on sgRNAs design.

关键词: CRISPR/Cas     Aid-TG     gene editing     sgRNA design     web server    

Impacts of climate change on optimal mixture design of blended concrete considering carbonation and chloride

Xiao-Yong WANG

《结构与土木工程前沿(英文)》 2020年 第14卷 第2期   页码 473-486 doi: 10.1007/s11709-020-0608-5

摘要: Many studies on the mixture design of fly ash and slag ternary blended concrete have been conducted. However, these previous studies did not consider the effects of climate change, such as acceleration in the deterioration of durability, on mixture design. This study presents a procedure for the optimal mixture design of ternary blended concrete considering climate change and durability. First, the costs of CO emissions and material are calculated based on the concrete mixture and unit prices. Total cost is equal to the sum of material cost and CO emissions cost, and is set as the objective function of the optimization. Second, strength, slump, carbonation, and chloride ingress models are used to evaluate concrete properties. The effect of different climate change scenarios on carbonation and chloride ingress is considered. A genetic algorithm is used to find the optimal mixture considering various constraints. Third, illustrative examples are shown for mixture design of ternary blended concrete. The analysis results show that for ternary blended concrete exposed to an atmospheric environment, a rich mix is necessary to meet the challenge of climate change, and for ternary blended concrete exposed to a marine environment, the impact of climate change on mixture design is marginal.

关键词: ternary blended concrete     climate change     optimal mixture design     carbonation     chloride ingress    

Structural optimal design of a swing vane compressor

Junjie MA,Xiang CHEN,Zongchang QU

《能源前沿(英文)》 2019年 第13卷 第4期   页码 764-769 doi: 10.1007/s11708-016-0449-z

摘要: In this paper, a novel swing vane rotary compressor (SVC) was introduced, which had significant advantages—simple mechanism, reduced frictional loss, reliable operation, and a comparatively higher compression ratio. Based on the swing vane compressor geometry model, thermodynamic model and kinetic model, the mathematical model of optimum design was established, and further theoretical and experimental studies were conducted. The length of the cylinder, radius of the rotor and cylinder were defined as design variables and the reciprocal of EER as objective function. The complex optimization method was adopted to study the structure of the swing vane compressor. The theoretical model could provide an effective method for predicting compressor performance, which would also contribute to structural optimization of the SVC. The study shows that the friction loss of the compressor are greatly reduced by optimized design in a given initial value, and the EER increased by 8.55%.

关键词: swing vane compressor     simulation     optimization design    

Numerical investigation and optimal design of fiber Bragg grating based wind pressure sensor

Xiangjie WANG, Danhui DAN, Rong XIAO, Xingfei YAN

《结构与土木工程前沿(英文)》 2017年 第11卷 第3期   页码 286-292 doi: 10.1007/s11709-017-0415-9

摘要: A wind pressure sensor based on fiber Bragg grating (FBG) for engineering structure was investigated in this paper. We established a transaction model of wind pressure to strain and proposed a method of temperature compensation. By finite element analysis, the basic parameters of the sensor were optimized with the aim of maximum strain under the basic wind pressure proposed in relative design code in China taking geometrical non-linearity into consideration. The result shows that the wind pressure sensor we proposed is well performed and have good sensing properties, which means it is a technically feasible solution.

关键词: wind pressure measurement     wind pressure sensor     fiber Bragg grating     optimal design    

Optimal design of a linkage–cam mechanism-based redundantly actuated parallel manipulator

《机械工程前沿(英文)》 2021年 第16卷 第3期   页码 451-467 doi: 10.1007/s11465-021-0634-6

摘要: A redundantly actuated parallel manipulator (RAPM) with mixed translational and rotational degrees of freedom (DOFs) is challenged for its dimensionally homogeneous Jacobian modeling and optimal design of architecture. In this paper, a means to achieve redundant actuation by adding kinematic constraints is introduced, which reduces the DOFs of the end-effector (EE). A generic dimensionally homogeneous Jacobian is developed for this type of RAPMs, which maps the generalized velocities of three points on the EE to the joint velocities. A new optimization algorithm derived from this dimensionally homogeneous Jacobian is proposed for the optimal design of this type of RAPMs. As an example, this paper presents a spatial RAPM involving linkages and cam mechanisms. This RAPM has 4 DOFs and 6 translational actuations. The linkage lengths and the position of the universal joints of the RAPM are optimized based on the dimensionally homogeneous Jacobian.

关键词: redundant actuation     parallel manipulator     linkage–cam mechanism     Jacobian     optimal design    

Analysis and optimal design of an underactuated finger mechanism for LARM hand

Shuangji YAO, Marco CECCARELLI, Giuseppe CARBONE, Qiang ZHAN, Zhen LU

《机械工程前沿(英文)》 2011年 第6卷 第3期   页码 332-343 doi: 10.1007/s11465-011-0229-8

摘要:

This paper aims to present general design considerations and optimality criteria for underactuated mechanisms in finger designs. Design issues related to grasping task of robotic fingers are discussed. Performance characteristics are outlined as referring to several aspects of finger mechanisms. Optimality criteria of the finger performances are formulated after careful analysis. A general design algorithm is summarized and formulated as a suitable multi-objective optimization problem. A numerical case of an underactuated robot finger design for Laboratory of Robotics and Mechatronics (LARM) hand is illustrated with the aim to show the practical feasibility of the proposed concepts and computations.

关键词: robotic finger     underactuated mechanisms     design considerations    

Toward autonomous mining: design and development of an unmanned electric shovel via point cloud-basedoptimal trajectory planning

《机械工程前沿(英文)》 2022年 第17卷 第3期 doi: 10.1007/s11465-022-0686-2

摘要: With the proposal of intelligent mines, unmanned mining has become a research hotspot in recent years. In the field of autonomous excavation, environmental perception and excavation trajectory planning are two key issues because they have considerable influences on operation performance. In this study, an unmanned electric shovel (UES) is developed, and key robotization processes consisting of environment modeling and optimal excavation trajectory planning are presented. Initially, the point cloud of the material surface is collected and reconstructed by polynomial response surface (PRS) method. Then, by establishing the dynamical model of the UES, a point to point (PTP) excavation trajectory planning method is developed to improve both the mining efficiency and fill factor and to reduce the energy consumption. Based on optimal trajectory command, the UES performs autonomous excavation. The experimental results show that the proposed surface reconstruction method can accurately represent the material surface. On the basis of reconstructed surface, the PTP trajectory planning method rapidly obtains a reasonable mining trajectory with high fill factor and mining efficiency. Compared with the common excavation trajectory planning approaches, the proposed method tends to be more capable in terms of mining time and energy consumption, ensuring high-performance excavation of the UES in practical mining environment.

关键词: autonomous excavation     unmanned electric shovel     point cloud     excavation trajectory planning    

Experiment and optimal design of a collection device for a residual plastic film baler

Qi NIU,Xuegeng CHEN,Chao JI,Jie WU

《农业科学与工程前沿(英文)》 2015年 第2卷 第4期   页码 347-354 doi: 10.15302/J-FASE-2015077

摘要: It is imperative to carry out research on residual plastic film collection technology to solve the serious problem of farmland pollution. The residual plastic film baler was designed as a package for film strip collection, cleaning and baling. The collection device is a core component of the baler. Response surface analysis was used in this study to optimize the structure and working parameters for improving the collection efficiency of residual film and the impurity of film package. The results show that the factors affecting the collection rate of residual film and the impurity of the film package are the speed ratio ( ) between the trash removal roller and eccentric collection mechanism, the number ( ) and the mounting angle ( ) of spring teeth in the same revolution plane. For the collection rate, the importance of the three factors are in the order, . Meanwhile, for the impurity, the importance of three factors are in the order, . When the speed ratio, the mounting angle and the number of spring teeth was set at 1.6°, 45°, and 8°, respectively, the collection rate of residual film was 88.9% and the impurity of residual film package was 14.2% for the baler.

关键词: residual film     collection device     collection rate of residual film     impurity of film package     optimization     baler    

Optimal design of steel skeletal structures using the enhanced genetic algorithm methodology

Tugrul TALASLIOGLU

《结构与土木工程前沿(英文)》 2019年 第13卷 第4期   页码 863-889 doi: 10.1007/s11709-019-0523-9

摘要: This study concerns with the design optimization of steel skeletal structures thereby utilizing both a real-life specification provisions and ready steel profiles named hot-rolled I sections. For this purpose, the enhanced genetic algorithm methodology named EGAwMP is utilized as an optimization tool. The evolutionary search mechanism of EGAwMP is constituted on the basis of generational genetic algorithm (GGA). The exploration capacity of EGAwMP is improved in a way of dividing an entire population into sub-populations and using of a radial basis neural network for dynamically adjustment of EGAwMP’s genetic operator parameters. In order to improve the exploitation capability of EGAwMP, the proposed neural network implementation is also utilized for prediction of more accurate design variables associating with a new design strategy, design codes of which are based on the provisions of LRFD_AISC V3 specification. EGAwMP is applied to determine the real-life ready steel profiles for the optimal design of skeletal structures with 105, 200, 444, and 942 members. EGAwMP accomplishes to increase the quality degrees of optimum designations Furthermore, the importance of using the real-life steel profiles and design codes is also demonstrated. Consequently, EGAwMP is suggested as a design optimization tool for the real-life steel skeletal structures.

关键词: design optimization     genetic algorithm     multiple populations     neural network    

Optimal dome design considering member-related design constraints

Tugrul TALASLIOGLU

《结构与土木工程前沿(英文)》 2019年 第13卷 第5期   页码 1150-1170 doi: 10.1007/s11709-019-0543-5

摘要: This study proposes to optimize the design of geometrically nonlinear dome structures. A new Multi-objective Optimization Algorithm named Pareto Archived Genetic Algorithm (PAGA), which has an ability of integrating the nonlinear structural analysis with the provisions of American Petroleum Institute specification is employed to optimize the design of ellipse and sphere-shaped dome configurations. Thus, it is possible to investigate how the qualities of optimal designations vary considering the shape, size, and topology-related design variables. Furthermore, the computing efficiency of PAGA is evaluated considering six multi-objective optimization algorithms and eight quality measuring indicators. It is shown that PAGA has a capability of both exploring an increased number of pareto solutions and predicting a pareto front with a higher convergence degree. Moreover, the inclusion of shape-related design variables leads to a decrease in both the weights of dome structures and their load-carrying capacities. However, the designer easily determines the most requested optimal design through the archiving feature of PAGA. Thus, it is also demonstrated that the proposed optimal design procedure increases the correctness degree in the evaluation of optimal dome designs through the tradeoff analysis. Consequently, PAGA is recommended as an optimization tool for the design optimization of geometrically nonlinear dome structures.

关键词: dome structure     geometric nonlinearity     multi-objective optimization     API RP2A-LRFD    

Multi-objective optimal design of braced frames using hybrid genetic and ant colony optimization

Mehdi BABAEI,Ebrahim SANAEI

《结构与土木工程前沿(英文)》 2016年 第10卷 第4期   页码 472-480 doi: 10.1007/s11709-016-0368-4

摘要: In this article, multi-objective optimization of braced frames is investigated using a novel hybrid algorithm. Initially, the applied evolutionary algorithms, ant colony optimization (ACO) and genetic algorithm (GA) are reviewed, followed by developing the hybrid method. A dynamic hybridization of GA and ACO is proposed as a novel hybrid method which does not appear in the literature for optimal design of steel braced frames. Not only the cross section of the beams, columns and braces are considered to be the design variables, but also the topologies of the braces are taken into account as additional design variables. The hybrid algorithm explores the whole design space for optimum solutions. Weight and maximum displacement of the structure are employed as the objective functions for multi-objective optimal design. Subsequently, using the weighted sum method (WSM), the two objective problem are converted to a single objective optimization problem and the proposed hybrid genetic ant colony algorithm (HGAC) is developed for optimal design. Assuming different combination for weight coefficients, a trade-off between the two objectives are obtained in the numerical example section. To make the final decision easier for designers, related constraint is applied to obtain practical topologies. The achieved results show the capability of HGAC to find optimal topologies and sections for the elements.

关键词: multi-objective     hybrid algorithm     ant colony     genetic algorithm     displacement     weighted sum method     steel braced frames    

On the improvement design of dynamic characteristics for the roller follower of a variable-speed plate

Hui Ching FAN, Hong Sen YAN

《机械工程前沿(英文)》 2012年 第7卷 第1期   页码 5-15 doi: 10.1007/s11465-012-0310-y

摘要:

Without modifying the cam contour, a cam mechanism with a variable input speed trajectory offers an alternative solution to flexibly achieve kinematic and dynamic characteristics, and then decrease the follower’s residual vibration. Firstly, the speed trajectory of cam is derived by employing Bezier curve, and motion continuity conditions are investigated. Then the motion characteristics between the plate cam and its roller follower are derived. To analyze the residual vibration, a single degree of freedom dynamic model of the elastic cam-follower system is introduced. Based on the motion equation derived from the dynamic model, the residual vibration of the follower is yielded. The design procedure to improve the kinematic and dynamic motion characteristics is presented and two design examples with discussions are provided. Finally, the simulations of the kinematic and dynamic models by ADAMS are carried out and verified that the design models as well as the performances of the mechanism are feasible.

关键词: cam mechanism     variable input speed     kinematic design     dynamic design     optimal design    

Optimal portfolio design of energy storage devices with financial and physical right market

《能源前沿(英文)》 2022年 第16卷 第1期   页码 95-104 doi: 10.1007/s11708-021-0788-2

摘要: With the continuous development of the spot market, in the multi-stage power market environment with the day-ahead market and right market, the study associated with the portfolio of energy storage devices requires that attention should be paid to transmission congestion and power congestion. To maximize the profit of energy storage and avoid the imbalance of power supply and consumption and the risk of node price fluctuation caused by transmission congestion, this paper presents a portfolio strategy of energy storage devices with financial/physical contracts. First, the concepts of financial/physical transmission rights and financial/physical storage rights are proposed. Then, the portfolio models of financial contract and physical contract are established with the conditional value-at-risk to measure the risks. Finally, the portfolio models are verified through the test data of the Pennsylvania-New Jersey-Maryland (PJM) electric power spot market, and the comparison between the risk aversion of portfolios based on financial/physical contract with the portfolio of the market without rights. The simulation results show that the portfolio models proposed in this paper can effectively avoid the risk of market price fluctuations.

关键词: portfolio     node price fluctuation     transmission right     energy storage right     risk aversion    

提高在线模型识别平台效率的多目标最优实验设计框架 Article

Arun Pankajakshan, Conor Waldron, Marco Quaglio,  Asterios Gavriilidis, Federico Galvanin

《工程(英文)》 2019年 第5卷 第6期   页码 1049-1059 doi: 10.1016/j.eng.2019.10.003

摘要:

自动化和数字化方面的最新进展使得物理设备与其对应的虚拟设备紧密集成,从而促进了实时建模与多个过程的自动优化。此类系统提供了丰富且不断更新的数据环境,使得系统随着时间的推移做出决策,并将过程推向最优目标成为可能。在许多制造过程中,为了实现整体最优过程,必须同时评估与过程性能和成本有关的多个目标函数。本文提出了一个多目标最优实验设计框架,用于提高在线模型识别平台的效率。所提出的框架能够灵活权衡实验设计解决方案,这些解决方案可以在线计算(即在执行实验期间)。将该框架应用于流动反应器中动力学模型在线识别的案例研究,并确定了微反应器中苯甲酸(benzoic acid, BA)和乙醇酯化的动力学模型。

 

关键词: 多目标优化     最优实验设计     在线    

Design and control optimization of energy systems of smart buildings today and in the near future

Shengwei WANG, Wenjie GANG

《工程管理前沿(英文)》 2017年 第4卷 第1期   页码 58-66 doi: 10.15302/J-FEM-2017005

摘要: Buildings contribute to a major part of energy consumption in urban areas, especially in areas like Hong Kong which is full of high-rise buildings. Smart buildings with high efficiency can reduce the energy consumption largely and help achieve green cities or smart cities. Design and control optimization of building energy systems therefore plays a significant role to obtain the optimal performance. This paper introduces a general methodology for the design and control optimization of building energy systems in the life cycle. When the design scheme of building energy systems is optimized, primary steps and related issues are introduced. To improve the operation performance, the optimal control strategies that can be used by different systems are presented and key issues are discussed. To demonstrate the effect of the methods, the energy system of a high-rise building is introduced. The design on the chilled water pump system and cooling towers is improved. The control strategies for chillers, pumps and fresh air systems are optimized. The energy saving and cost from the design and control optimization methods are analyzed. The presented methodology will provide users and stakeholders an effective approach to improve the energy efficiency of building energy systems and promote the development of smart buildings and smart cities.

关键词: Design optimization     Optimal control     Smart building     Energy efficiency    

标题 作者 时间 类型 操作

A PLATFORM TO AID SELECT THE OPTIMAL TOOL TO DESIGN GUIDE RNAS

期刊论文

Impacts of climate change on optimal mixture design of blended concrete considering carbonation and chloride

Xiao-Yong WANG

期刊论文

Structural optimal design of a swing vane compressor

Junjie MA,Xiang CHEN,Zongchang QU

期刊论文

Numerical investigation and optimal design of fiber Bragg grating based wind pressure sensor

Xiangjie WANG, Danhui DAN, Rong XIAO, Xingfei YAN

期刊论文

Optimal design of a linkage–cam mechanism-based redundantly actuated parallel manipulator

期刊论文

Analysis and optimal design of an underactuated finger mechanism for LARM hand

Shuangji YAO, Marco CECCARELLI, Giuseppe CARBONE, Qiang ZHAN, Zhen LU

期刊论文

Toward autonomous mining: design and development of an unmanned electric shovel via point cloud-basedoptimal trajectory planning

期刊论文

Experiment and optimal design of a collection device for a residual plastic film baler

Qi NIU,Xuegeng CHEN,Chao JI,Jie WU

期刊论文

Optimal design of steel skeletal structures using the enhanced genetic algorithm methodology

Tugrul TALASLIOGLU

期刊论文

Optimal dome design considering member-related design constraints

Tugrul TALASLIOGLU

期刊论文

Multi-objective optimal design of braced frames using hybrid genetic and ant colony optimization

Mehdi BABAEI,Ebrahim SANAEI

期刊论文

On the improvement design of dynamic characteristics for the roller follower of a variable-speed plate

Hui Ching FAN, Hong Sen YAN

期刊论文

Optimal portfolio design of energy storage devices with financial and physical right market

期刊论文

提高在线模型识别平台效率的多目标最优实验设计框架

Arun Pankajakshan, Conor Waldron, Marco Quaglio,  Asterios Gavriilidis, Federico Galvanin

期刊论文

Design and control optimization of energy systems of smart buildings today and in the near future

Shengwei WANG, Wenjie GANG

期刊论文