资源类型

期刊论文 112

会议视频 3

年份

2024 2

2023 10

2022 11

2021 10

2020 13

2019 5

2018 11

2017 4

2016 4

2015 3

2014 4

2013 2

2012 3

2011 3

2010 4

2009 5

2008 3

2007 5

2006 4

2005 2

展开 ︾

关键词

产品设计 2

农业科学 2

农产品 2

CA-QFD方法 1

CIMS 1

IHNI-1 1

MCNP 1

ORIGEN2 1

TRIZ 1

“互联网 +”现代农业 1

不确定性 1

中草药化学成分 1

主动回收 1

二氧化硅 1

云制造 1

产品优化设计 1

产品制备 1

产品工艺，自适应设计，制造大数据，数据挖掘，知识发现 1

产品平台 1

展开 ︾

检索范围：

排序： 展示方式：

Oral product input to the GI tract: GIS an oral product performance technology

Gordon L. Amidon, Yasuhiro Tsume

《化学科学与工程前沿（英文）》 2017年 第11卷 第4期   页码 516-520 doi: 10.1007/s11705-017-1658-7

摘要： The patient receives a pharmaceutical product, not a drug. The pharmaceutical products are formulated with a drug, an active ingredient to produce the maximum therapeutic effect after oral absorption. Therefore, it is the product we must optimize for the patients. In order to assure the safety and efficacy of pharmaceutical products, we need an predictive tool for oral product performance in patients. Currently, we are a surprisingly long way from accomplishing that objective. If the 20th century was the ‘age of the drug’, i.e., the ‘magic bullet’, the 21st century must become the ‘age of the guided missile’, i.e., the delivery system, including the form of the active pharmaceutical ingredient (API) (‘drug’). The physical form of the drug and the delivery system must be optimized to maximize the therapeutic benefits of pharmaceutical products for humans. Oral immediate release (IR) dosage forms cannot be optimal for all drugs or likely even any drugs (APIs). Still, the formulation of pharmaceutical products has to be optimized for patients. But how do we optimize oral delivery of drugs? It is usually through ‘trial and error’, in humans! We need a better way to optimize the oral dosage forms. We have suggested to select different dissolution methodologies for this optimization based on BCS Subclasses. In this article, we present the predicted drug dissolution profile of ketoconazole as a model drug from our laboratory utilizing a gastrointestinal simulator (GIS), which is an adaptation of the ASD system. GIS consists of three chambers representing stomach, duodenum, and jejunum, to create the human gastrointestinal tract-like environment and enable the control the gastric emptying rate. This dissolution system allows the monitoring of the drug dissolution phenomena and the observation of the supersaturation and the precipitation of pharmaceutical products, which is useful information to predict dissolution of pharmaceutical products. This system can provide the actual input needed to accurately predict the input into the systemic circulation required by many of the absorption prediction packages available today.

关键词： GIS     in vivo predictive dissolution     ketoconazole     BCS subclassification     supersaturation    

HTML PDF 收藏

Lean Product Development—Faster, Better … Cleaner?

Geert Letens

《工程管理前沿（英文）》 2015年 第2卷 第1期   页码 52-59 doi: 10.15302/J-FEM-2015007

摘要： To address this challenge, lean product development has emerged to become the leading improvement methodology for companies toward the creation of a competitive advantage on innovation and technology leadership. While lean product development has its origin in the best practice studies of Japanese car manufacturers such as Toyota, it has been further elaborated in defence and aerospace organizations over the last two decades, and recently empirical evidence has become available for successful introductions in sectors different from the traditionally-studied environments. The primary purpose of this work is to untangle the fuzziness that still surrounds lean product development and to ground the key aspects of lean product development based on insights from six studies published in a special issue of the on this topic. This demonstrates how better and faster product development can be achieved through the integration of lean principles with the best of more traditional new product development (NPD) practices, into a holistic system that can be characterised by value-focused and risk-based decision making, the socio-technical integration of people and process, improved project, pipeline and portfolio management, optimized knowledge management, and the creation of a learning organization. Unfortunately, while the increasing global competition offers the potential to improve the quality of life for many, the spirit of faster, better, and cheaper also threatens to endanger the future of our planet as a whole. As the majority of a product’s social and ecological impacts are committed in the design phase, it, therefore, seems imperative to investigate the integration of lean product development and eco-design principles. As a result, this work also explores the symbiosis of both approaches through the identification of tools and methods that can support the triple bottom-line goals for a sustainable future of life and business.

关键词： lean product development     sustainability engineering     responsible design    

HTML PDF 收藏

Review of sentiment analysis: An emotional product development view

《工程管理前沿（英文）》 2022年 第9卷 第4期   页码 592-609 doi: 10.1007/s42524-022-0227-z

摘要： Conveying consumers’ specific emotions in new products, referred to as emotional product development or emotional design, is strategically crucial for manufacturers. Given that sentiment analysis (SA) can extract and analyze people’s opinions, sentiments, attitudes, and perceptions regarding different products/services, SA-based emotional design may provide manufacturers with real-time, direct, and rapid decision support. Despite its considerable advancements and numerous survey and review articles, SA is seldom considered in emotional design. This study is among the first efforts to conduct a thorough review of SA from the view of emotional design. The comprehensive review of aspect-level SA reveals the following: 1) All studies focus on extracting product features by mixing technical product features and consumers’ emotional perceptions. Consequently, such studies cannot capture the relationships between technical and emotional attributes and thus cannot convey specific emotions to the new products. 2) Most studies use the English language in SA, but other languages have recently received more interest in SA. Furthermore, after conceptualizing emotion as Kansei and introducing emotional product development and Kansei Engineering, a review of the data-driven emotional design is then conducted. A few efforts start to study emotional design with the help of SA. However, these studies only focus on either analyzing consumers’ preferences on product features or extracting emotional opinions from online reviews, thus cannot realize data-driven emotional product development. Finally, some research opportunities are provided. This study opens a broad door to aspect-level SA and its integration with emotional product development.

关键词： sentiment analysis     emotion     product development     Kansei Engineering    

HTML PDF 收藏

An energy consumption prediction approach of die casting machines driven by product parameters

《机械工程前沿（英文）》 2021年 第16卷 第4期   页码 868-886 doi: 10.1007/s11465-021-0656-0

摘要： Die casting machines, which are the core equipment of the machinery manufacturing industry, consume great amounts of energy. The energy consumption prediction of die casting machines can support energy consumption quota, process parameter energy-saving optimization, energy-saving design, and energy efficiency evaluation; thus, it is of great significance for Industry 4.0 and green manufacturing. Nevertheless, due to the uncertainty and complexity of the energy consumption in die casting machines, there is still a lack of an approach for energy consumption prediction that can provide support for process parameter optimization and product design taking energy efficiency into consideration. To fill this gap, this paper proposes an energy consumption prediction approach for die casting machines driven by product parameters. Firstly, the system boundary of energy consumption prediction is defined, and subsequently, based on the energy consumption characteristics analysis, a theoretical energy consumption model is established. Consequently, a systematic energy consumption prediction approach for die casting machines, involving product, die, equipment, and process parameters, is proposed. Finally, the feasibility and reliability of the proposed energy consumption prediction approach are verified with the help of three die casting machines and six types of products. The results show that the prediction accuracy of production time and energy consumption reached 91.64% and 85.55%, respectively. Overall, the proposed approach can be used for the energy consumption prediction of different die casting machines with different products.

关键词： die casting machine     energy consumption prediction     product parameters    

HTML PDF 收藏

A hybrid method for product low-end disruptive innovation

《机械工程前沿（英文）》 2022年 第17卷 第3期 doi: 10.1007/s11465-022-0690-6

摘要： Product innovation is often a process for improving existing products. Low-end disruptive innovation (LDI) enables a product to meet the most price-sensitive customers in the low-end market. The existing LDI methods are mainly based on unnecessary characteristics of disruptive innovations. Thus, they cannot easily identify and respond to the LDI design needs. This study proposes a hybrid method for the product LDI in two levels of the product design based on the summarized definition and essential characteristics of LDI. Feasible areas of the product LDI are determined using a hybrid relational function model to identify the maturity of dominant technologies. The technologies are identified through the technical search and evaluation of the feasible area for innovation to form an initial LDI scheme. Then, the product function is optimized using the trimming concept of theory of inventive problem solving based on the characteristics of LDI. The final LDI scheme is formed and evaluated based on the essential characteristics of the product LDI. The feasibility of the proposed method is verified in the design of a new dropping pill machine.

关键词： low-end disruptive innovation     product design     design improvement     theory of inventive problem solving     TRIZ     trimming    

HTML PDF 收藏

Isomorphism analysis on generalized modules oriented to the distributed parameterized intelligent product

Shasha ZENG, Weiping PENG, Tiaoyu LEI

《机械工程前沿（英文）》 2020年 第15卷 第1期   页码 12-23 doi: 10.1007/s11465-019-0555-9

摘要： The distributed parameterized intelligent product platform (DPIPP) contains many agents of a product minimum approximate autonomous subsystem (generalized module). These distributed agents communicate, coordinate, and cooperate using their knowledge and skills and eventually accomplish the design for mass customization in a loosely coupled environment. In this study, a new method of isomorphism analysis on generalized modules oriented to DPIPP is proposed. First, on the basis of the bill of material partition and generalized module mining, the parameters of the main characteristics are extracted to construct the main characteristic parameter matrix. Second, similarity calculation of generalized modules is realized by improving the clustering using representatives algorithm, and isomorphism model sets are obtained. Generalized modules with a similar structure are combined to complete the isomorphism analysis. The effectiveness of the proposed method is verified by taking high- and medium-pressure valve data as an example.

关键词： distributed parameterized intelligent product platform     generalized module     isomorphism analysis     product family    

HTML PDF 收藏

2019 highlights of the structural revision of natural product

Zongjia Chen, Mark A. Rizzacasa

《化学科学与工程前沿（英文）》 2021年 第15卷 第3期   页码 595-601 doi: 10.1007/s11705-020-1971-4

HTML PDF 收藏

Massively efficient filter for topology optimization based on the splitting of tensor product structure

《机械工程前沿（英文）》 2022年 第17卷 第4期 doi: 10.1007/s11465-022-0710-6

摘要： In this work, we put forward a massively efficient filter for topology optimization (TO) utilizing the splitting of tensor product structure. With the aid of splitting technique, the traditional weight matrices of B-splines and non-uniform rational B-spline implicit filters are decomposed equivalently into two or three submatrices, by which the sensitivity analysis is reformulated for the nodal design variables without altering the optimization process. Afterwards, an explicit sensitivity filter, which is decomposed by the splitting pipeline as that applied to implicit filter, is established in terms of the tensor product of the axial distances between adjacent element centroids, and the corresponding sensitivity analysis is derived for elemental design variables. According to the numerical results, the average updating time for the design variables is accelerated by two-order-of-magnitude for the decomposed filter compared with the traditional filter. In addition, the memory burden and computing time of the weight matrix are decreased by six- and three-order-of-magnitude for the decomposed filter. Therefore, the proposed filter is massively improved by the splitting of tensor product structure and delivers a much more efficient way of solving TO problems in the frameworks of isogeometric analysis and finite element analysis.

关键词： topology optimization     isogeometric analysis     finite element analysis     tensor product structure     sensitivity analysis    

HTML PDF 收藏

Highlights in agri-product quality and safety

Guanghong ZHOU

《农业科学与工程前沿（英文）》 2018年 第5卷 第3期   页码 289-290 doi: 10.15302/J-FASE-2018236

摘要：

关键词： valign=     top     class=     J_zhaiyao    

HTML PDF 收藏

General closed-form inverse kinematics for arbitrary three-joint subproblems based on the product of

《机械工程前沿（英文）》 2022年 第17卷 第2期 doi: 10.1007/s11465-022-0681-7

摘要： The inverse kinematics problems of robots are usually decomposed into several Paden–Kahan subproblems based on the product of exponential model. However, the simple combination of subproblems cannot solve all the inverse kinematics problems, and there is no common approach to solve arbitrary three-joint subproblems in an arbitrary postural relationship. The novel algebraic geometric (NAG) methods that obtain the general closed-form inverse kinematics for all types of three-joint subproblems are presented in this paper. The geometric and algebraic constraints are used as the conditions precedent to solve the inverse kinematics of three-joint subproblems. The NAG methods can be applied in the inverse kinematics of three-joint subproblems in an arbitrary postural relationship. The inverse kinematics simulations of all three-joint subproblems are implemented, and simulation results indicating that the inverse solutions are consistent with the given joint angles validate the general closed-form inverse kinematics. Huaque III minimally invasive surgical robot is used as the experimental platform for the simulation, and a master–slave tracking experiment is conducted to verify the NAG methods. The simulation result shows the inverse solutions and six sets given joint angles are consistent. Additionally, the mean and maximum of the master–slave tracking experiment for the closed-form solution are 0.1486 and 0.4777 mm, respectively, while the mean and maximum of the master–slave tracking experiment for the compensation method are 0.3188 and 0.6394 mm, respectively. The experiments results demonstrate that the closed-form solution is superior to the compensation method. The results verify the proposed general closed-form inverse kinematics based on the NAG methods.

关键词： inverse kinematics     Paden–Kahan subproblems     three-joint subproblems     product of exponential     closed-form solution    

HTML PDF 收藏

Knowledge-based competitive strategy using direct customer experience for automobile product development

Peter HODGES, Shuh Yuan LIOU,

《机械工程前沿（英文）》 2010年 第5卷 第1期   页码 33-46 doi: 10.1007/s11465-009-0080-3

摘要： The automobile product development (PD) design space continually increases in size and complexity. In this dynamic environment, firms must identify competitive strategies that maintain or increase financial return. Firms can compete on several factors including price/cost, time-to-market, or differentiation (e.g., function or quality). Here, we envision that differentiation through expertise in integration can be a successful strategy in the automotive industry. Expertise in integration requires attention to knowledge management, which is crucial for competitive advantage []. A key component of the PD process is the acquisition of data about customers’ responses to vehicle performance and the rapid use of that information in the development of new products. The paper proposes a system for collecting near real-time data about responses to vehicle performance and its integration with recent developments in design and analysis. The proposed system would collect customer psychophysical response data, correlate it with vehicle parameter response data, and apply this information with feasible design automation to provide reduced cycle time, improved quality, and greater customer satisfaction. The paper discusses some relevant technological and legal constraints and concludes that such a system is feasible, can provide a near-term competitive advantage, and in the long-term, in some form, will be necessary for success.

关键词： product development     strategy     knowledge management    

HTML PDF 收藏

Autohydrolysis treatment of bamboo and potassium oxalate (KCO) activation of bamboo product for CO capture

《化学科学与工程前沿（英文）》 2024年 第18卷 第4期 doi: 10.1007/s11705-024-2402-8

HTML PDF 收藏

Continuous flow pyrolysis of virgin and waste polyolefins: a comparative study, process optimization and product

《化学科学与工程前沿（英文）》 doi: 10.1007/s11705-024-2429-x

摘要： Under optimal process conditions, pyrolysis of polyolefins can yield ca. 90 wt % of liquid product, i.e., combination of light oil fraction and heavier wax. In this work, the experimental findings reported in a selected group of publications concerning the non-catalytic pyrolysis of polyolefins were collected, reviewed, and compared with the ones obtained in a continuously operated bench-scale pyrolysis reactor. Optimized process parameters were used for the pyrolysis of waste and virgin counterparts of high-density polyethylene, low-density polyethylene, polypropylene and a defined mixture of those (i.e., 25:25:50 wt %, respectively). To mitigate temperature drops and enhance heat transfer, an increased feed intake is employed to create a hot melt plastic pool. With 1.5 g·min–1 feed intake, 1.1 L·min–1 nitrogen flow rate, and a moderate pyrolysis temperature of 450 °C, the formation of light hydrocarbons was favored, while wax formation was limited for polypropylene-rich mixtures. Pyrolysis of virgin plastics yielded more liquid (maximum 73.3 wt %) than that of waste plastics (maximum 66 wt %). Blending polyethylenes with polypropylene favored the production of liquids and increased the formation of gasoline-range hydrocarbons. Gas products were mainly composed of C3 hydrocarbons, and no hydrogen production was detected due to moderate pyrolysis temperature.

关键词： waste plastics     polyolefins     chemical recycling     pyrolysis     alternative fuels     waste-to-energy    

HTML PDF 收藏

An improved low-complexity sum-product decoding algorithm for low-density parity-check codes

Michaelraj Kingston ROBERTS,Ramesh JAYABALAN

《信息与电子工程前沿（英文）》 2015年 第16卷 第6期   页码 511-518 doi: 10.1631/FITEE.1400269

摘要： In this paper, an improved low-complexity sum-product decoding algorithm is presented for low-density parity-check (LDPC) codes. In the proposed algorithm, reduction in computational complexity is achieved by utilizing fast Fourier transform (FFT) with time shift in the check node process. The improvement in the decoding performance is achieved by utilizing an optimized integer constant in the variable node process. Simulation results show that the proposed algorithm achieves an overall coding gain improvement ranging from 0.04 to 0.46 dB. Moreover, when compared with the sum-product algorithm (SPA), the proposed decoding algorithm can achieve a reduction of 42%-67% of the total number of arithmetic operations required for the decoding process.

关键词： Computational complexity     Coding gain     Fast Fourier transform (FFT)     Low-density parity-check (LDPC) codes     Sum-product algorithm (SPA)    

HTML PDF 收藏

Evaluation of factors influencing soluble microbial product in submerged MBR through hybrid ASM model

Fangyue LI, Joachim BEHRENDT, Knut WICHMANN, Ralf OTTERPOHL

《环境科学与工程前沿（英文）》 2009年 第3卷 第2期   页码 226-235 doi: 10.1007/s11783-009-0008-5

摘要： In this study, a mathematical model was established to predict the formation of the soluble microbial product (SMP) in a submerged membrane bioreactor. The developed model was calibrated under the reference condition. Simulation results were in good agreement with the measured results under the reference condition. The calibrated model was then used in the scenario studies to evaluate the effect of three chosen operating parameters: hydraulic retention time (HRT), dissolved oxygen concentration, and sludge retention time (SRT). Simulation results revealed that the SMP dominated the soluble organic substances in the supernatant. The scenario studies also revealed that the HRT can be decreased to 1 h without deteriorating the effluent quality; dissolved oxygen concentration in the reactor can be kept at 2-3 mg/L to maintain the effluent quality, reduce the content of SMP, and minimize operating costs; the optimal SRT can be controlled to 10-15 d to achieve complete nitrification process, less membrane fouling potential, and acceptable organic removal efficiency.

关键词： hybrid activated sludge model (ASM)     membrane bioreactor (MBR)     soluble microbial product (SMP)    

HTML PDF 收藏

标题 作者 时间 类型 操作

Oral product input to the GI tract: GIS an oral product performance technology

Gordon L. Amidon, Yasuhiro Tsume

期刊论文

Lean Product Development—Faster, Better … Cleaner?

Geert Letens

期刊论文

Review of sentiment analysis: An emotional product development view

期刊论文

An energy consumption prediction approach of die casting machines driven by product parameters

期刊论文

A hybrid method for product low-end disruptive innovation

期刊论文

Isomorphism analysis on generalized modules oriented to the distributed parameterized intelligent product

Shasha ZENG, Weiping PENG, Tiaoyu LEI

期刊论文

2019 highlights of the structural revision of natural product

Zongjia Chen, Mark A. Rizzacasa

期刊论文

Massively efficient filter for topology optimization based on the splitting of tensor product structure

期刊论文

Highlights in agri-product quality and safety

Guanghong ZHOU

期刊论文

General closed-form inverse kinematics for arbitrary three-joint subproblems based on the product of

期刊论文

Knowledge-based competitive strategy using direct customer experience for automobile product development

Peter HODGES, Shuh Yuan LIOU,

期刊论文

Autohydrolysis treatment of bamboo and potassium oxalate (KCO) activation of bamboo product for CO capture

期刊论文

Continuous flow pyrolysis of virgin and waste polyolefins: a comparative study, process optimization and product

期刊论文

An improved low-complexity sum-product decoding algorithm for low-density parity-check codes

Michaelraj Kingston ROBERTS,Ramesh JAYABALAN

期刊论文

Evaluation of factors influencing soluble microbial product in submerged MBR through hybrid ASM model

Fangyue LI, Joachim BEHRENDT, Knut WICHMANN, Ralf OTTERPOHL

期刊论文