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Decellularized extracellular matrix mediates tissue construction and regeneration

《医学前沿（英文）》 2022年第16卷第1期页码 56-82 doi: 10.1007/s11684-021-0900-3

摘要： Contributing to organ formation and tissue regeneration, extracellular matrix (ECM) constituents provide tissue with three-dimensional (3D) structural integrity and cellular-function regulation. Containing the crucial traits of the cellular microenvironment, ECM substitutes mediate cell–matrix interactions to prompt stem-cell proliferation and differentiation for 3D organoid construction in vitro or tissue regeneration in vivo. However, these ECMs are often applied generically and have yet to be extensively developed for specific cell types in 3D cultures. Cultured cells also produce rich ECM, particularly stromal cells. Cellular ECM improves 3D culture development in vitro and tissue remodeling during wound healing after implantation into the host as well. Gaining better insight into ECM derived from either tissue or cells that regulate 3D tissue reconstruction or organ regeneration helps us to select, produce, and implant the most suitable ECM and thus promote 3D organoid culture and tissue remodeling for in vivo regeneration. Overall, the decellularization methodologies and tissue/cell-derived ECM as scaffolds or cellular-growth supplements used in cell propagation and differentiation for 3D tissue culture in vitro are discussed. Moreover, current preclinical applications by which ECM components modulate the wound-healing process are reviewed.

关键词： decellularized extracellular matrix 3D culture organoids tissue repair

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关于3D打印技术在医学模具以及再生组织和器官方面的应用综述

Kan Wang, Chia-Che Ho, Chuck Zhang, Ben Wang

《工程（英文）》 2017年第3卷第5期页码 653-662 doi: 10.1016/J.ENG.2017.05.013

摘要：随着三维（3D）打印和3D 生物打印技术的快速发展，许多研究人员已经开始使用增材制造技术来生产具有多种功能的医学模具。本文综述了3D 打印和3D 生物打印技术在制作功能性医学模具和生物结构方面的应用。特别讨论了3D 打印功能性医学模具（即组织模拟医学模具、放射性医学模具和生理医学模具）及被用于再生组织和器官的3D 生物打印模具的制备（即混合模式支架材料、可转换支架和集成传感器）工艺、发展现状以及未来发展趋势

关键词： 3D打印 3D生物打印医学模具再生组织/器官支架

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Animage-based approach to the reconstruction of ancient architectures by extracting and arranging 3D

Divya Udayan J,HyungSeok KIM,Jee-In KIM

《信息与电子工程前沿（英文）》 2015年第16卷第1期页码 12-27 doi: 10.1631/FITEE.1400141

摘要： The objective of this research is the rapid reconstruction of ancient buildings of historical importance using a single image. The key idea of our approach is to reduce the infinite solutions that might otherwise arise when recovering a 3D geometry from 2D photographs. The main outcome of our research shows that the proposed methodology can be used to reconstruct ancient monuments for use as proxies for digital effects in applications such as tourism, games, and entertainment, which do not require very accurate modeling. In this article, we consider the reconstruction of ancient Mughal architecture including the Taj Mahal. We propose a modeling pipeline that makes an easy reconstruction possible using a single photograph taken from a single view, without the need to create complex point clouds from multiple images or the use of laser scanners. First, an initial model is automatically reconstructed using locally fitted planar primitives along with their boundary polygons and the adjacency relation among parts of the polygons. This approach is faster and more accurate than creating a model from scratch because the initial reconstruction phase provides a set of structural information together with the adjacency relation, which makes it possible to estimate the approximate depth of the entire structural monument. Next, we use manual extrapolation and editing techniques with modeling software to assemble and adjust different 3D components of the model. Thus, this research opens up the opportunity for the present generation to experience remote sites of architectural and cultural importance through virtual worlds and real-time mobile applications. Variations of a recreated 3D monument to represent an amalgam of various cultures are targeted for future work.

关键词： Digital reconstruction 3D virtual world 3D spatial components Vision and scene understanding

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增材制造（3D打印）发展趋势 Perspective

卢秉恒, 李涤尘, 田小永

《工程（英文）》 2015年第1卷第1期页码 85-89 doi: 10.15302/J-ENG-2015012

摘要：

增材制造又称为3D打印，在过去30年间取得了快速发展并展示出前所未有的发展潜力。同时，这项发展潜力巨大的技术对传统工业也产生了不可估量的影响。3D打印技术将会推动生产模式的变革，通过实现5个“任意”的工艺发展，将会为制造行业带来一个以定制化制造为特征的新时代。3D打印的技术进步及其与传统制造工艺的融合，将推动制造业在材料研发、产品设计、生产工艺等方面进一步创新发展。最终，3D打印技术将与等材制造、减材制造形成三足鼎立局面，共同分享整个社会的制造业价值。

关键词：增材制造 3D打印制造模式定制化制造创新设计

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3D打印技术在多个领域取得进展

Chris Palmer

《工程（英文）》 2020年第6卷第6期页码 590-592 doi: 10.1016/j.eng.2020.04.005

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Construction of digital 3D magic-cube organization structure for innovation-driven manufacturing

《工程管理前沿（英文）》 2023年第10卷第3期页码 373-390 doi: 10.1007/s42524-022-0237-x

摘要： Owing to the heterogeneity between functional units and resource scarcity, manufacturing firms have been struggling with intra-organizational coordination for productivity and innovation. Traditional organizational structures, such as linear-functional and matrix, may cause responsibility division and independent goals (Shahani, 2020), and are more difficult to be adopted by large-sized innovative manufacturing firms for quantity production. This is based on a review of several new forms of organization (i.e., network organization, multiteam system, and platform organization) compared with the traditional forms of organization (i.e., linear, matrix, and business unit organization, among others). This study proposes a three-dimensional (3D) magic-cube organizational structure, considering the product dimensions, business, and administration. Moreover, the characteristics, propositions of system operation, system dynamic model, and working model of the 3D magic-cube organization are described. Finally, the 3D model is applied in a Chinese manufacturing firm to test its effectiveness. By redesigning the post and pay system, the pilot organization establishes a project-driven and cross-functional coordination mechanism, positively affecting the firm’s financial profit, output value, labor productivity, and income of per capita. The proposed 3D model can be adopted by large- or medium-sized manufacturing firms for product development and innovation. The implications of both practice and theory are also discussed in this study.

关键词： innovation manufacturing 3D magic-cube organization structure coordination

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Characterization of 3D microstructure, thermal conductivity, and heat flow of cement-based foam using

《结构与土木工程前沿（英文）》 2021年第15卷第3期页码 643-651 doi: 10.1007/s11709-021-0709-9

摘要： This study presents the results of the 3D microstructure, thermal conductivity, and heat flow in cement-based foams and examines their changes with a range of densities. Images were captured using X-ray micro computed tomography (micro-CT) imaging technique on cement-based foam samples prepared with densities of 400, 600, and 800 kg/m³. These images were later simulated and quantified using 3D data visualization and analysis software. Based on the analysis, the pore volume of 11000 µm³ was determined across the three densities, leading to optimal results. However, distinct pore diameters of 15 µm for 800 kg/m³, and 20 µm for 600 and 400 kg/m³ were found to be optimum. Most of the pores were spherical, with only 10% appearing elongated or fractured. In addition, a difference of 15% was observed between the 2D and 3D porosity results. Moreover, a difference of 5% was noticed between the experimentally measured thermal conductivity and the numerically predicted value and this variation was constant across the three cast densities. The 3D model showed that heat flows through the cement paste solids and with an increase in porosity this flow reduces.

关键词： 3D pore volume distribution X-ray tomography 3D shape factor heat flow

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面向医学应用的3D 打印技术现状综述 Review

严倩,董汉华,苏瑾,韩建华,宋波,魏青松, 史玉升

《工程（英文）》 2018年第4卷第5期页码 729-742 doi: 10.1016/j.eng.2018.07.021

摘要： 3D 打印技术具有解决目前这些问题的潜力，可用于快速制造个性化组织工程支架、细胞原位修复组织缺陷，甚至直接打印组织和器官。本文总结了3D 打印在医学领域相关研究和最新进展的四个层次，介绍了不同类型的生物医用材料，并讨论了医学应用中3D 打印所需材料和构建体外细胞质基质（ECM）存在的问题和未来的发展方向。

关键词： 3D 打印植入体支架生物医学材料

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Origami-Based Design for 4D Printing of 3D Support-Free Hollow Structures

《工程（英文）》 2022年第12卷第5期页码 70-82

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支架与组织的设计及3D打印 Review

安佳, Joanne Ee Mei Teoh, Ratima Suntornnond, Chee Kai Chua

《工程（英文）》 2015年第1卷第2期页码 261-268 doi: 10.15302/J-ENG-2015061

摘要：

目前，组织工程学中应用3D打印工艺的情况越来越多。本文介绍3D打印技术在组织工程学应用领域的最前沿研究，尤其侧重于计算机辅助支架设计系统的开发、功能梯度支架的直接3D打印、选择性激光烧结 (SLS) 和熔融沉积成型 (FDM) 工艺建模、利用微观和宏观特征进行支架间接增材制造、生物反应器的开发，以及3D/4D生物打印。本文还讨论3D打印的技术限制，进而突出新3D打印方法在组织工程学领域得到进一步改善的可能性。

关键词：快速原型制造 3D打印增材制造组织工程生物打印

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使用2D、3D和4D增材制造材料开发生物植入物 Review

刘果, 何云虎, 刘朋超, 陈舟, 陈绪梁, 万镭, 李莹, 吕坚

《工程（英文）》 2020年第6卷第11期页码 1232-1243 doi: 10.1016/j.eng.2020.04.015

摘要：但是，用于制造生物植入物的3D可打印材料仍然非常有限。本研究对用于生物植入物的2D、3D AM材料进行了概述。此外，在我们团队先前开发的4D打印陶瓷前驱体及陶瓷材料的基础上，受太极思想的启发，本文提出了一种简单而新颖的软硬集成4D增材制造概念，以应用于人体系统中复杂且动态的生物结构。多材料打印技术的发展，使得人们未来可以使用2D、3D、4D AM材料开发生物植入物和软硬集成生物结构。

关键词：生物打印 2D增材制造 3D打印 4D打印生物植入物

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Direct pyrolysis to convert biomass to versatile 3D carbon nanotubes/mesoporous carbon architecture:

《化学科学与工程前沿（英文）》 2023年第17卷第6期页码 679-690 doi: 10.1007/s11705-022-2266-8

摘要： The massive conversion of resourceful biomass to carbon nanomaterials not only opens a new avenue to effective and economical disposal of biomass, but provides a possibility to produce highly valued functionalized carbon-based electrodes for energy storage and conversion systems. In this work, biomass is applied to a facile and scalable one-step pyrolysis method to prepare three-dimensional (3D) carbon nanotubes/mesoporous carbon architecture, which uses transition metal inorganic salts and melamine as initial precursors. The role of each employed component is investigated, and the electrochemical performance of the attained product is explored. Each component and precise regulation of their dosage is proven to be the key to successful conversion of biomass to the desired carbon nanomaterials. Owing to the unique 3D architecture and integration of individual merits of carbon nanotubes and mesoporous carbon, the as-synthesized carbon nanotubes/mesoporous carbon hybrid exhibits versatile application toward lithium-ion batteries and Zn-air batteries. Apparently, a significant guidance on effective conversion of biomass to functionalized carbon nanomaterials can be shown by this work.

关键词： biomass direct pyrolysis 3D CNTs/MC hybrid lithium-ion batteries Zn-air batteries

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Seepage analysis of Upper Gotvand Dam concerning gypsum karstification (2D and 3D approaches)

Jamshid SADREKARIMI, Majid KIYANI, Behnam FAKHRI, Mohammad Javad VAHDATIRAD, Amin BARARI

《结构与土木工程前沿（英文）》 2011年第5卷第1期页码 71-78 doi: 10.1007/s11709-010-0083-5

摘要： Upper Gotvand Dam is constructed on the Karun River at the south west of Iran. In this paper, 2D and 3D models of the dam together with the foundation and abutments were established, and several seepage analyses were carried out. Then, the gypsum veins that are scattered throughout the foundation ground were included in the models, and the seepage pattern, considering the dissolution law of gypsum, was analyzed. It was disclosed that the discharge fluxes obtained from 2D and 3D analyses are not similar, and the discharge flux in 3D model is about four times that of the 2D model. Also, the 3D model locates the phreatic surface somewhat higher than the 2D model. This means that the 2D model estimates lower pore water pressure pattern in comparison with the 3D model. These may be attributed to the fact that with 2D model the lateral components of vectors of seepage velocity are ignored. In the current case, the rate of increase of discharge flux due to dissolution of gypsum veins was obtained to be a third-order function of the aperture width. In spite of the fact that the grout curtain is designed to be about 170 m deep, however, complete dissolve of gypsum will severely increase the discharge flux through the foundation ground.

关键词： Upper Gotvand Dam seepage analysis gypsum veins 3D model discharge flux

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工业4.0复合材料3D打印方法

Bronwyn Fox, Aleksander Subic

《工程（英文）》 2019年第5卷第4期页码 621-623 doi: 10.1016/j.eng.2019.06.003

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轴向零泊松比结构心血管支架的设计、3D打印与表征 Article

王程锦, 张磊, 方永聪, 孙伟

《工程（英文）》 2021年第7卷第7期页码 979-990 doi: 10.1016/j.eng.2020.02.013

摘要：近年来，增材制造技术（也称3D打印技术）在医疗器械领域得到了广泛的应用。本文提出了一种新型的微螺杆挤出式3D打印系统，并利用该系统制备了一种具有零泊松比（ZPR）结构的支架。首先进行了初步的单丝挤出试验来研究合适的制造参数；随后，制备了具有不同几何结构的3D打印支架，并通过扫描电子显微镜（SEM）观察分析支架表面形貌；最后，对不同参数的3D打印支架进行了力学性能评价和初步的生物学评价总之，基于微螺杆挤出式3D打印系统具有制备个性化支架的潜力。

关键词：增材制造 3D打印螺杆挤出心血管支架零泊松比