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基于IP骨干网的虚拟专用网理论与实现

李秀忠

《中国工程科学》 2002年第4卷第3期页码 84-91

摘要：

讨论了虚拟专用网（VPN），尤其是IP-VPN的相关方面。在此基础上分析了IP-VPN的虚拟专用路由网（VPRN）和虚拟专用局域网（VPLS）两种类型。着重讨论了VPRN的两种实现机制——边界网关协议/多协议标记交换（BGP/MPLS）和虚拟路由器（VR），并进行了比较。实现了一种VPLS——虚拟局域网（VLAN）。最后从理论上探讨了基于网络的VPN的服务质量（QoS）并提出了一种VPN QoS的实现途径。

关键词：虚拟专用路由网（VPRN）虚拟专用局域网段（VPLS）边界网关协议/多协议标记交换（BGP/MPLS）虚拟路由器（VR）最坏情况加权公平排队（WF²Q）随机早期检测（RED

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早期监测肝细胞癌的新型非蛋白生物标志物 Review

Ghassan K. Abou-Alfa, 吴琳, Augusto Villanueva

《工程（英文）》 2021年第7卷第10期页码 1369-1374 doi: 10.1016/j.eng.2021.02.020

摘要： font-family:等线">肝细胞癌（HCC）早期检测是对处于早期阶段的肝细胞癌进行检出的方法然而，对于早期HCC，目前仍然缺乏具有高度灵敏性和特异性的监测生物标志物。近年来，人们对循环系统中可检测到的肿瘤源性分子特征进行了大量研究，比如循环肿瘤脱氧核糖核酸（ctDNA）和循环肿瘤核糖核酸（ctRNA），以探讨它们作为多种肿瘤类型的候选非侵入性生物标志物的潜力。本文汇总了目前有关早期HCC检测的新方法及应用的研究。

关键词：肝细胞癌早期检测生物标志物液体活检

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Effects of rape straw and red mud on extractability and bioavailability of cadmium in a calcareous soil

Junxing YANG,Liqun WANG,Jumei LI,Dongpu WEI,Shibao CHEN,Qingjun GUO,Yibing MA

《环境科学与工程前沿（英文）》 2015年第9卷第3期页码 419-428 doi: 10.1007/s11783-014-0674-9

摘要： Screening of cost-effective soil amendments is important to develop “ ” remediation techniques for cadmium (Cd) contaminated soils. In this study, different soil amendments, including red mud, a by-product of the alumina industry, and acid-treated, nano-treated by nano-particle milling, nano and acid-treated red muds, zeolite, corn straw, and rape straw, were evaluated to immobilize Cd in two added levels (2 and 5 mg Cd·kg soil) in a calcareous soil by single and sequential extractions and by cucumber ( L.) pot experiments. Results indicated that cruciferous rape straw significantly decreased the concentrations of water soluble, extractable Cd in soils, and Cd in cucumber plants, and it was more effective than gramineous corn straw. Also, red mud generally decreased the extractability and bioavailability of Cd added to calcareous soils more effectively than zeolite. Furthermore, the efficiency of red mud could be increased by the treatment of nano-particle milling due to the increase in specific surface area of red mud. It is potential to use rape straw and red mud as soil amendments to develop a cost-effective and efficient “ ” remediation technology for Cd mildly contaminated calcareous soils.

关键词： red mud rape straw cadmium immobilization calcareous soil

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Facile discovery of red blood cell deformation and compromised membrane/skeleton assembly in Prader–Willi

《医学前沿（英文）》 2022年第16卷第6期页码 946-956 doi: 10.1007/s11684-022-0962-x

摘要： Prader–Willi syndrome (PWS) is a rare congenital disease with genetic alterations in chromosome 15. Although genetic disorders and DNA methylation abnormalities involved in PWS have been investigated to a significant degree, other anomalies such as those in erythrocytes may occur and these have not been clearly elucidated. In the present study, we uncovered slight anemia in children with PWS that was associated with increased red blood cell (RBC) distribution width (RDW) and contrarily reduced hematocrit (HCT) values. Intriguingly, the increased ratio in RDW to HCT allowed sufficient differentiation between the PWS patients from the healthy controls and, importantly, with individuals exhibiting conventional obesity. Further morphologic examinations revealed a significant deformity in erythrocytes and mild hemolysis in PWS patients. Comprehensive mechanistic investigations unveiled compromised membrane skeletal assembly and membrane lipid composition, and revealed a reduced F-actin/G-actin ratio in PWS patients. We ascribed these phenotypic changes in erythrocytes to the observed genetic defects, including DNA methylation abnormalities. Our collective data allowed us to uncover RBC deformation in children with PWS, and this may constitute an auxiliary indicator of PWS in early childhood.

关键词： Prader–Willi syndrome early diagnosis erythrocyte deformation membrane skeleton membrane lipid

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大菱鲆疾病早期快速检测方法——胶体金免疫层析试纸的研制与建立

王蔚芳,柴书军,刘庆堂,雷霁霖,丁福红,洪磊,刘新富,苏柯

《中国工程科学》 2012年第14卷第2期页码 8-13

摘要：

使用成分单一的牛血清白蛋白(BSA)为模拟病原，以胶体金标记兔抗血清(即大菱鲆免疫球蛋白多抗)作为检测示踪物，并分别将BSA和葡萄球菌A蛋白印记到硝酸纤维素膜上制成检测线和对照线，通过一系列工艺创制与组装配套，首次成功制备了一套完整的大菱鲆抗体快速检测试纸。采用大菱鲆抗BSA血清作为阳性样本，以健康大菱鲆血清作为阴性样本，用以检验试纸的性能，并与酶联免疫吸附实验(ELISA)法检测结果相比较。结果表明：本试纸检测抗体的特异性与敏感性均很高，与ELISA方法相当，而且使用方便，不需专业技能和额外的试剂与辅助仪器设备，5 min内即可用裸眼获得观察结果，很适合于基层生产操作及户外调研使用。以该实验为基础建立起来的抗体检测试纸，亦可推广应用于其他病害抗体的检测，可为鱼类疾病早期发生提供简易、快捷和操作性强的诊断方法。

关键词：大菱鲆抗体试纸现场快速检测胶体金免疫层析疾病

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Precise regulation of acid pretreatment for red mud SCR catalyst: Targeting on optimizing the acidity

《环境科学与工程前沿（英文）》 2022年第16卷第7期 doi: 10.1007/s11783-021-1447-x

摘要：

• The optimum SCR activity was realized by tuning the acid pretreatment.

关键词： Air pollution control Nitrogen oxides Selective catalytic reduction Red mud Solid waste utilization

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Materials sustainability for environment: Red-mud treatment

Brajendra Mishra, Sumedh Gostu

《化学科学与工程前沿（英文）》 2017年第11卷第3期页码 483-496 doi: 10.1007/s11705-017-1653-z

摘要： Bayer’s process revolutionized the extraction of aluminum from the bauxite ores. However, the hydrothermal extraction of alumina is associated with the generation of a byproduct, red-mud consisting of undissolved solids composed of iron oxides, sodium alumino silicates, titania, silica and rare earth elements. The accumulation of red-mud (or bauxite residue) in the world is 30 billion metric tons produced at a rate of 125 million tons per annum (2013). Utilization of red-mud for constructional purposes, wastewater treatment, metallurgical products, and pigments are listed. Metallurgical processing efforts of red-mud to generate various value added products such as pig iron, direct reduced iron slag wool, magnetite, titania, iron carbides are presented in the article.

关键词： red-mud processing waste management sustainability valorization

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cellulose nanocrystal cross-linked chitosan foam with high adsorption capacity for removal of acid red

《化学科学与工程前沿（英文）》 2023年第17卷第7期页码 853-866 doi: 10.1007/s11705-022-2256-x

摘要： The discharge of large amounts of dye-containing wastewater seriously threats the environment. Adsorbents have been adopted to remove these dyes present in the wastewater. However, the high adsorption capacity, predominant pH-responsibility, and excellent recyclability are three challenges to the development of efficient adsorbents. The poly(acryloxyethyl trimethylammonium chloride)-graft-dialdehyde cellulose nanocrystals were synthesized in our work. Subsequently, the cationic dialdehyde cellulose nanocrystal cross-linked chitosan nanocomposite foam was fabricated via freeze-drying of the hydrogel. Under the optimal ratio of the cationic dialdehyde cellulose nanocrystal/chitosan (w/w) of 12/100, the resultant foam (Foam-12) possesses excellent absorption properties, such as high porosity, high content of active sites, strong acid resistance, and high amorphous region. Then, Foam-12 was applied as an eco-friendly adsorbent to remove acid red 134 (a representative of anionic dyes) from aqueous solutions. The maximum dye adsorption capacity of 1238.1 mg∙g^‒1 is achieved under the conditions of 20 mg∙L^‒1 adsorbents, 100 mg∙L^‒1 dye, pH 3.5, 24 h, and 25 °C. The dominant adsorption mechanism for the anionic dye adsorption is electrostatic attraction, and Foam-12 can effectively adsorb acid red 134 at pH 2.5–5.5 and be desorbed at pH 8. Its easy recovery and good reusability are verified by the repeated acid adsorption–alkaline desorption experiments.

关键词： chitosan foam cellulose nanocrystals acid red 134 adsorption

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Response of bacterial communities to short-term pyrene exposure in red soil

Jingjing PENG, Hong LI, Jianqiang SU, Qiufang ZHANG, Junpeng RUI, Chao CAI

《环境科学与工程前沿（英文）》 2013年第7卷第4期页码 559-567 doi: 10.1007/s11783-013-0501-8

摘要： Pyrene, a representative polycyclic aromatic hydrocarbon (PAH) compound produced mainly from incomplete combustion of fossil fuels, is hazardous to ecosystem health. However, long-term exposure studies did not detect any significant effects of pyrene on soil microorganism. In this study, short-term microcosm experiments were conducted to identify the immediate effect of pyrene on soil bacterial communities. A freshly-collected pristine red soil was spiked with pyrene at 0, 10, 100, 200, and 500 mg·kg and incubated for one day and seven days. The bacterial communities in the incubated soils were analyzed using 16S rRNA sequencing and terminal restriction fragment length polymorphism (T-RFLP) methods. The results revealed high bacterial diversity in both unspiked and pyrene-spiked soils. Only at the highest pyrene-spiking rate of 500 mg·kg , two minor bacteria groups of the identified 14 most abundant bacteria groups were completely suppressed. Short-term exposure to pyrene resulted in dominance of Proteobacteria in soil, followed by Acidobacteria, Firmutes, and Bacteroidetes. Our findings showed that bacterial community structure did respond to the presence of pyrene but recovered rapidly from the perturbation. The intensity of impact and the rate of recovery showed some pyrene dosage-dependent trends. Our results revealed that different levels of pyrene may affect the bacterial community structure by suppressing or selecting certain groups of bacteria. It was also found that the bacterial community was most susceptible to pyrene within one day of the chemical addition.

关键词： pyrene bacterial communities terminal restriction fragment length polymorphism short-term exposure rank-abundance plots

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Effects of red and blue LEDs on

Lili CHEN, Xuzhang XUE, Yadong YANG, Fei CHEN, Jie ZHAO, Xiquan WANG, Alam Tariful KHAN, Yuegao HU

《农业科学与工程前沿（英文）》 2018年第5卷第2期页码 197-205 doi: 10.15302/J-FASE-2018224

摘要： The objectives of this study were to investigate the effects of red and blue LEDs on growth and microtuberization of potato ( ) single-node cuttings. Explants were incubated under 6 light treatments: 100% red LEDs (R), 75% red LEDs+ 25% blue LEDs (3RB), 50% red LEDs+ 50% blue LEDs (RB), 25% red LEDs+ 75% blue LEDs (R3B), 100% blue LEDs (B) and white LEDs (W). Most of the growth and physiological parameters were significantly higher in 3RB than W. Enhancement of leaf area and chlorophyll concentrations were obtained in B. Leaf stomata were elliptical with the lowest density in 3RB. However, those in W were round in shape, and those with the smallest size and the highest density were observed in R. Most of the characteristics of microtuberization were also improved in 3RB. The combined spectra of red and blue LEDs increased the number of large microtubers. The fresh weight of individual microtubers in R and W were increased, but not their number. These results suggest that, of the treatments assessed, 3RB is optimal for the growth of potato plantlets and the combination of red and blue LEDs is beneficial for microtuberization.

关键词： blue LED microtuber plant tissue culture potato plantlets in vitro red LED

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A MYB-INDUCED MECHANISM FOR ENHANCED ASCORBATE IN RED-FLESHED APPLES

《农业科学与工程前沿（英文）》 2021年第8卷第2期

摘要：

The results presented in “The anthocyanin biosynthetic regulator MdMYB1 positively regulates ascorbic acid biosynthesis in apple” (An et al., this issue) provide evidence for a new mechanism for the elevation of ascorbate concentration in apple. Using a red-fleshed apple breeding population, the authors show how the anthocyanin-regulating MYB transcription factor, MdMYB1, also increases ascorbate concentrations by directly activating transcription of the dehydroascorbate reductase gene MdDHAR. This gene recycles oxidized ascorbate back to ascorbate, leading to elevated concentrations of vitamin C. These red-fleshed apples have enhanced concentrations of both anthocyanins and ascorbate, both of which are appealing traits for the development of healthier apples.

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Lignin-derived dual-function red light carbon dots for hypochlorite detection and anti-counterfeiting

《化学科学与工程前沿（英文）》 2023年第17卷第7期页码 966-975 doi: 10.1007/s11705-022-2244-1

摘要： The efficient utilization of natural lignin, which is the main by-product of the cellulose industry, is crucial for enhancing its economic value, alleviating the environmental burden, and improving ecological security. By taking advantage of the large sp² hybrid domain of lignin and introducing amino functional groups, new lignin-derived carbon dots (SPN-CDs) with red fluorescence were successfully synthesized. Compared with green and blue fluorescent materials, red SPN-CDs have desirable anti-interference properties of short-wave background and exhibit superior luminescence stability. The SPN-CDs obtained exhibited sensitive and distinctive visible color with fluorescence-dual responses toward hypochlorite. Considering this feature, a portable, low-cost, and sensitive fluorescence sensing paper with a low limit of detection of 0.249 μmol∙L^–1 was fabricated using the SPN-CDs for hypochlorite detection. Furthermore, a new type of visible-light and fluorescence dual-channel information encryption platform was constructed. Low-concentration hypochlorite can be employed as an accessible and efficient information encryption/decryption stimulus, as well as an information “eraser”, facilitating a safe and diversified transmission and convenient decryption of information. This work opens new avenues for high-value-added applications of lignin-based fluorescent materials.

关键词： alkali lignin red light carbon dots hypochlorite encryption and anti-counterfeiting

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Insight into the promotion mechanism of activated carbon on the monolithic honeycomb red mud catalyst

《环境科学与工程前沿（英文）》 2021年第15卷第5期 doi: 10.1007/s11783-020-1337-7

摘要：

• Activated carbon was proposed to be an efficient accelerant for molded red mud catalyst.

关键词： NO_x Selective catalytic reduction Iron-based catalyst Red mud Monolithic catalyst Activated carbon

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nanoarchitecture for an optimal combination of photothermal and chemodynamic therapy functions of CuS cores with red

《化学科学与工程前沿（英文）》 2023年第17卷第12期页码 2144-2155 doi: 10.1007/s11705-023-2362-4

摘要： This study introduces multifunctional silica nanoparticles that exhibit both high photothermal and chemodynamic therapeutic activities, in addition to luminescence. The activity of the silica nanoparticles is derived from their plasmonic properties, which are a result of infusing the silica nanoparticles with multiple Cu_2–xS cores. This infusion process is facilitated by a recoating of the silica nanoparticles with a cationic surfactant. The key factors that enable the internal incorporation of the Cu_2–xS cores and the external deposition of red-emitting carbon dots are identified. The Cu_2–xS cores within the silica nanoparticles exhibit both self-boosting generation of reactive oxygen species and high photothermal conversion efficacy, which are essential for photothermal and chemodynamic activities. The silica nanoparticles’ small size (no more than 70 nm) and high colloidal stability are prerequisites for their cell internalization. The internalization of the red-emitting silica nanoparticles within cells is visualized using fluorescence microscopy techniques. The chemodynamic activity of the silica nanoparticles is associated with their dark cytotoxicity, and the mechanisms of cell death are evaluated using an apoptotic assay. The photothermal activity of the silica nanoparticles is demonstrated by significant cell death under near-infrared (1064 nm) irradiation.

关键词： copper sulfide nanoparticles chemodynamic therapy photothermal therapy carbon dots silica nanoparticles

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A MYB-INDUCED MECHANISM FOR ENHANCED ASCORBATE IN RED-FLESHED APPLES

Richard V. ESPLEY, Kuilin WANG

《农业科学与工程前沿（英文）》页码 356-357 doi: 10.15302/J-FASE-2021381

摘要： The results presented in “The anthocyanin biosynthetic regulator MdMYB1 positively regulates ascorbic acid biosynthesis in apple” (An et al., this issue) provide evidence for a new mechanism for the elevation of ascorbate concentration in apple. Using a red-fleshed apple breeding population, the authors show how the anthocyanin-regulating MYB transcription factor, MdMYB1, also increases ascorbate concentrations by directly activating transcription of the dehydroascorbate reductase gene . This gene recycles oxidized ascorbate back to ascorbate, leading to elevated concentrations of vitamin C. These red-fleshed apples have enhanced concentrations of both anthocyanins and ascorbate, both of which are appealing traits for the development of healthier apples.

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标题作者时间类型操作

基于IP骨干网的虚拟专用网理论与实现

李秀忠

期刊论文

早期监测肝细胞癌的新型非蛋白生物标志物

Ghassan K. Abou-Alfa, 吴琳, Augusto Villanueva

期刊论文

Effects of rape straw and red mud on extractability and bioavailability of cadmium in a calcareous soil

Junxing YANG,Liqun WANG,Jumei LI,Dongpu WEI,Shibao CHEN,Qingjun GUO,Yibing MA

期刊论文

Facile discovery of red blood cell deformation and compromised membrane/skeleton assembly in Prader–Willi