Synthesis and application of superparamagnetic iron oxide nanoparticles in targeted therapy and imaging of cancer

2011, Volume 5, Issue 4

Abstract

Keywords

Related Research

Frontiers of Medicine >> 2011, Volume 5, Issue 4 doi: 10.1007/s11684-011-0162-6

Synthesis and application of superparamagnetic iron oxide nanoparticles in targeted therapy and imaging of cancer

Department of Nuclear Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

Available online: 2011-12-05

HTML0 PDF 4 Collect 0

Next Previous

Abstract

Superparamagnetic iron oxide (SPIO) nanoparticles have become a popular strategy of cancer treatment and molecular imaging because of their versatile properties and biocompatibility. A variety of studies have shown the exciting potential of functionalized SPIO nanoparticles, such as surface-coated, targeted ligand-conjugated, and/or drug-loaded SPIO nanoparticles, as powerful tools for targeted imaging and therapy. Moreover, the applications of SPIO nanoparticles that integrate diagnosis and therapy in SPIO nanoparticles facilitate the monitoring of therapeutic efficacy during treatment. In the present review, we primarily concentrate on the recent advancements in the field of SPIO nanoparticles in terms of synthesis, targeted therapy, and cancer imaging.

Keywords

nanoparticles ; superparamagnetic iron oxide ; targeted therapy ; molecular imaging ; cancer

Related Research