2014, Volume 8, Issue 2
Frontiers of Medicine >> 2014, Volume 8, Issue 2 doi: 10.1007/s11684-014-0333-3
Comprehensive treatment of acute-on-chronic liver failure in a patient with hepatitis B: a case report
1. Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
2. Department of Liver Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
3. Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
4. Shanghai Institute of Liver Diseases, Shanghai 200032, China
Next Previous
Abstract
The clinical data of a patient with acute-on-chronic liver failure were analyzed retrospectively. The patient has suffered from hepatitis B for 30 years. His liver function deteriorated, yielding Child-Pugh grade C and reaching a model for end-stage liver disease score of 33 points within a short period; this condition was complicated with highly active variceal bleeding and coagulation system failure (PT > 100 s). The patient also presented hepatocellular carcinoma. Comprehensive treatments included effective inhibition of hepatitis B virus replication and intensive care support. Piggyback orthotopic liver transplantation was performed as the final treatment. The patient recovered uneventfully and was discharged after surgery.
京公网安备 11010502051620号
