Frontiers of Medicine >> 2021, Volume 15, Issue 2 doi: 10.1007/s11684-021-0837-6
Degradation of SARS-CoV-2 receptor ACE2 by the E3 ubiquitin ligase Skp2 in lung epithelial cells
. State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.. State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences & University of Chinese Academy of Sciences, Beijing 100101, China.. Hubei University of Medicine, Shiyan 442000, China.. Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.. Department of Pulmonary and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.. Guizhou University School of Medicine, Guiyang 550025, China.. School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100029, China
Next Previous
Abstract
Keywords
SARS-CoV-2 ; tobacco smoke ; benzo(a)pyrene ; ACE2 ; Skp2