Frontiers of Chemical Science and Engineering
>> 2016,
Volume 10,
Issue 1
doi:
10.1007/s11705-015-1550-2
REVIEW ARTICLE
Microfluidics for cell-cell interactions: A review
School of Life Science, Beijing Institute of Technology, Beijing 100081, China
Accepted: 2015-12-29
Available online: 2016-02-29
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Abstract
Microfluidic chip has been applied in various biological fields owing to its low-consumption of reagents, high throughput, fluidic controllability and integrity. The well-designed microscale intermediary is also ideal for the study of cell biology. Particularly, microfluidic chip is helpful for better understanding cell-cell interactions. A general survey of recent publications would help to generalize the designs of the co-culture chips with different features. With ingenious and combinational utilization, the chips facilitate the implementation of some special co-culture models that are highly concerned in a different spatial and temporal way.