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Frontiers of Chemical Science and Engineering >> 2020, Volume 14, Issue 3 doi: 10.1007/s11705-019-1863-7

Glyco-functionalised quantum dots and their progress in cancer diagnosis and treatment

. School of Chemistry, University of East Anglia, Norwich, NR4 7TJ, UK.. Norwich Medical School, University of East Anglia, Norwich, NR4 7TJ, UK

Accepted: 2019-09-29 Available online:2019-09-29

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Despite all major breakthroughs in recent years of research, we are still unsuccessful to effectively diagnose and treat cancer that has express and metastasizes. Thus, the development of a novel approach for cancer detection and treatment is crucial. Recent progress in Glyconanotechnology has allowed the use of glycans and lectins as bio-functional molecules for many biological and biomedical applications. With the known advantages of quantum dots (QDs) and versatility of carbohydrates and lectins, Glyco-functionalised QD is a new prospect in constructing biomedical imaging platform for cancer behaviour study as well as treatment. In this review, we aim to describe the current utilisation of Glyco-functionalised QDs as well as their future prospective to interpret and confront cancer.

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