As part of a Network for Earthquake Engineering Simulation research project led by researchers at the University of Washington with collaborators at University at Buffalo, and Taiwan National Center for Research on Earthquake Engineering, a self-centering steel plate shear wall (SC-SPSW) system has been developed to achieve enhanced seismic performance objectives, including recentering. The SC-SPSW consists of thin steel infill panels, referred to as web plates that serve as the primary lateral load-resisting and energy dissipating element of the system. Post-tensioned (PT) beam-to-column connections provide system recentering capabilities. A performance-based design procedure has been developed for the SC-SPSW, and a series of nonlinear response history analyses have been conducted to verify intended seismic performance at multiple hazard levels. Quasi-static subassembly tests, quasi-static and shake table tests of scaled three-story specimens, and pseudo-dynamic tests of two full-scale two-story SC-SPSWs have been conducted. As a culmination of this multi-year, multi-institutional project, this paper will present an overview of the SC-SPSW numerical and experimental research programs. This paper will also discuss innovative PT connection and web plate designs that were investigated to improve constructability, resilience, and seismic performance and that can be applied to other self-centering and steel plate shear wall systems.