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Frontiers of Environmental Science & Engineering >> 2019, Volume 13, Issue 3 doi: 10.1007/s11783-019-1128-1

Detection of presumed genes encoding beta-lactamases by sequence based screening of metagenomes derived from Antarctic microbial mats

1. 1Molecular Microbiology Unit, Clemente Estable Biological Research Insitute, UdelaR, Montevideo 11600, Uruguay
2. Microbiology Laboratory, Faculty of Agronomy, UdelaR, Montevideo 12900, Uruguay
3. Genome Organization and Evolution Laboratory, Ecology and Evolution Department, Faculty of Sciences, UdelaR, Montevideo 11400, Uruguay
4. Molecular Biophysics and Integrated Bioimaging, BSISB Imaging Program, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
5. Bacteial Ecology Laboratory, Ecology Institute, National Autonomous University of Mexico, CDMX 04510, Mexico
6. UNAM, Yucatan Technology and Science Park, Merida 97302, Mexico
7. Argentine Antarctic Institute, Buenos Aires 1650, Argentina
8. Biotechnology Unit, Faculty of Pharmacy and Biochemistry, Nanobiotec Institute UBA-CONICET, Buenos Aires 1113, Argentina

Available online: 2019-06-26

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Abstract

• Beta-lactamase genes were found in all samples from distant places in Antarctica.

• Class C beta-lactamase coding genes were the most frequently found.

• Diversity of sequences exceeds that of the beta-lactamases from clinical environment.

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