[ 1 ] Rees M. On the future: prospects for humanity. Princeton: Princeton University Press; 2018. link1

[ 2 ] GBD 2017 Population and Fertility Collaborators. Population and fertility by age and sex for 195 countries and territories, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018;392 (10159):1995–2051. link1

[ 3 ] United Nations Department of Economic and Social Affairs/Population Division. World population prospects 2019 [Internet]. New York: United Nations Department of Economic and Social Affairs/Population Division; c2019 [cited 2019 Oct 13]. Available from: https://population.un.org/wpp/Graphs/ Probabilistic/POP/TOT/900. link1

[ 4 ] Probabilistic Population Projections based on the World Population Prospects 2019 [Internet]. United Nations; c2019 [cited 2019 Oct 13]. Available from: https://population.un.org/wpp/Download/Probabilistic/Population/. link1

[ 5 ] Magdy S. Dozens of refugees feared dead as boat bound for Europe capsizes in the Mediterranean Sea [Internet]. The Independent. 2019 Aug 27 [cited 2019 Oct 13]. Available from: https://www.independent.co.uk/news/world/europe/ refugee-boat-capsize-mediterranean-libya-sudan-rescue-a9080621.html. link1

[ 6 ] Bennett CE, Thomas R, Williams M, Zalasiewicz J, Edgeworth M, Miller H, et al. The broiler chicken as a signal of a human reconfigured biosphere. R Soc Open Sci 2018;5(12):180325. link1

[ 7 ] Bar-On YM, Phillips R, Milo R. The biomass distribution on Earth. Proc Natl Acad Sci USA 2018;115(25):6506–11. link1

[ 8 ] Collins M, Knutti R, Arblaster J, Dufresne JL, Fichefet T, Friedlingstein P, et al. Long-term climate change: projections, commitments and irreversibility. In: Stocker TF, Qin D, Plattner GK, Tignor M, Allen SK, Boschung J, et al., editors. Climate Change 2013—the physical science basis Working Group I contribution to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change [Internet]. Geneva: Intergovernmental Panel on Climate Change; 2013 [cited 2019 Oct 13]. Available from: https://www.ipcc.ch/ report/ar5/wg1/long-term-climate-change-projections-commitments-andirreversibility/. link1

[ 9 ] IPCC. Special report on global warming of 1.5 C [Internet]. Geneva: Intergovernmental Panel on Climate Change; c2018 [cited 2019 Oct 13]. Available from: https://www.ipcc.ch/sr15/. link1

[10] EPA. Public health and environmental radiation protection standards for Yucca Mountain. Nevada (40 CFR Part 197) [Internet]. Washington, DC: US Environmental Protection Agency; [cited 2019 Oct 13]. Available from: https://www.epa.gov/radiation/public-health-and-environmental-radiationprotection-standards-yucca-mountain-nevada-40. link1

[11] World Nuclear Association. Generation IV nuclear reactors [Internet]. London: World Nuclear Association; c2016–2020 [cited 2019 Oct 13]. Available from: https://www.world-nuclear.org/information-library/nuclear-fuel-cycle/ nuclear-power-reactors/generation-iv-nuclear-reactors.aspx. link1

[12] The Climate Change Act. 2008 (2050 Target Amendment) Order 2019. UK Statutory Instruments; c2019 [cited 2019 Oct 13]. Available from: https:// www.legislation.gov.uk/uksi/2019/1056/contents/made. link1

[13] Enserink M. Scientists brace for media storm around controversial flu studies [Internet]. Science 2011 Nov 23 [cited 2019 Oct 13]. Available from: https:// www.sciencemag.org/news/2011/11/scientists-brace-media-storm-aroundcontroversial-flu-studies. link1

[14] Cyranoski D, Ledford H. Genome-edited baby claim provokes international outcry. Nature 2018;563:607–8. link1

[15] Collins CH. Gene Drive. A genetic tool that can alter—and potentially eliminate—entire species has taken a dramatic leap forward [Internet]. Scientific American; c2018 [cited 2019 Oct 13]. Available from: https:// www.scientificamerican.com/article/gene-drive1/. link1

[16] Baumgaertner E. As DIY gene editing gains popularity, ‘Someone is going to get hurt’ [Internet]. New York: The New York Times; c2018 [cited 2019 Oct 13]. Available from: https://www.nytimes.com/2018/05/14/science/biohackersgene-editing-virus.html. link1

[17] Silver D, Hubert T, Schrittwieser J, Hassabis D. AlphaZero: shedding new light on chess, shogi, and Go [Internet]. London: DeepMind; c2018 [cited 2019 Oct 13]. Available from: https://deepmind.com/blog/article/alphazero-sheddingnew-light-grand-games-chess-shogi-and-go. link1

[18] Kurzweil R. The age of spiritual machines. London: Penguin Random House; 2000. link1

[19] Philipkoski K. Ray Kurzweil’s plan: never die [Internet]. San Francisco: Wired; c2002 [cited 2019 Oct 13]. Available from: https://www.wired.com/2002/11/ ray-kurzweils-plan-never-die/. link1

[20] Pengelly M. Elon Musk considers move to Mars despite ‘good chance of death’ [Internet]. London: The Guardian; 2018 Nov 25 [cited 2019 Oct 13]. Available from: https://www.theguardian.com/technology/2018/nov/25/elon-muskmove-mars-chance-of-death. link1

[21] Francis Pope. Laudato si’: on care for our common home. Vatican: Vatican Press; 2015. link1

[22] Quinn L. Filming albatross chicks eating plastic [Internet]. BBC; [cited 2019 Oct 13]. Available from: https://www.bbc.co.uk/programmes/articles/3ddrZCyXkz 37jtyb71K0nc4/filming-albatross-chicks-eating-plastic. link1