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Frontiers of Agricultural Science and Engineering >> 2017, Volume 4, Issue 1 doi: 10.15302/J-FASE-2017133

Fluorescent properties and

. Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry; National Engineering Laboratory of Biomass Chemical Utilization/Key Laboratory of Biomass Energy and Material, Jiangsu Province, Nanjing 210042, China.. Department of Chemistry and Biochemistry, University of Michigan-Flint, Flint, MI 48502, USA

Accepted: 2017-02-27 Available online: 2017-03-06

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Abstract

A series of dehydroabietic acid-based diarylamines have been synthesized in order to investigate their fluorescent properties, photostability, cell toxicity and fluorescence imaging. The geometries as well as their molecular properties were optimized at the B3LYP/6-31G* level using Gaussian 03. The results indicate that molecular geometry, HOMO and LUMO energies, and energy gaps are important to predict absorption and fluorescent properties. Five of the compounds can be effectively taken up by human cervical carcinoma, human hepatocellular carcinoma SMMC-7721, human gastric cancer SGC-7901 and human lung adenocarcinoma A549 cells and strong blue fluorescent signals are detected in these cells. These compounds are potential candidates for fluorescent probes in biological diagnosis.

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