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2018, Volume 5, Issue 3

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Frontiers of Agricultural Science and Engineering >> 2018, Volume 5, Issue 3 doi: 10.15302/J-FASE-2018208

spp., foodborne pathogens threatening neonates and infants

1. School of Biotechnology, State Key Laboratory of Bioreactor Engineering, R&D Center of Separation and Extraction Technology in Fermentation Industry, East China University of Science and Technology, Shanghai 200237, China
2. Shanghai Collaborative Innovation Center for Biomanufacturing Technology (SCICBT), Shanghai 200237, China
3. Bioprocess Engineering Group, Agrotechnology and Food Sciences, Wageningen University and Research, 6700 AA Wageningen, the Netherlands

Accepted: 2018-04-23 Available online: 2018-07-31
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Abstract

Cronobacter spp. (formerly Enterobacter sakazakii) are special foodborne pathogens. Cronobacter infection can cause necrotizing enterocolitis, sepsis and meningitis in all age groups, especially neonates and infants, with a high fatality of up to 80%, although the infection is rare. Outbreaks of Cronobacter infection are epidemiologically proven to be associated with contaminated powdered infant formula (PIF). Cronobacter spp. can resist dry environments and survive for a long period in food with low water activity. Therefore, Cronobacter spp. have become serious pathogens of neonates and infants, as well as in the dairy industry. In this review, we present the taxonomy, pathogenesis, resistance, detection and control of Cronobacter spp.

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